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Items: 1 to 20 of 95

1.

The complex world of WNT receptor signalling.

Niehrs C.

Nat Rev Mol Cell Biol. 2012 Dec;13(12):767-79. doi: 10.1038/nrm3470. Epub 2012 Nov 15. Review.

PMID:
23151663
2.

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner.

Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F.

Nature. 2012 Apr 29;485(7397):195-200. doi: 10.1038/nature11019.

PMID:
22575959
3.

Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.

Nam JS, Turcotte TJ, Smith PF, Choi S, Yoon JK.

J Biol Chem. 2006 May 12;281(19):13247-57. Epub 2006 Mar 16.

4.

LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.

Glinka A, Dolde C, Kirsch N, Huang YL, Kazanskaya O, Ingelfinger D, Boutros M, Cruciat CM, Niehrs C.

EMBO Rep. 2011 Sep 30;12(10):1055-61. doi: 10.1038/embor.2011.175.

5.
6.

LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling.

Carmon KS, Lin Q, Gong X, Thomas A, Liu Q.

Mol Cell Biol. 2012 Jun;32(11):2054-64. doi: 10.1128/MCB.00272-12. Epub 2012 Apr 2. Erratum in: Mol Cell Biol. 2017 Jun 15;37(13):.

7.

R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling.

Wei Q, Yokota C, Semenov MV, Doble B, Woodgett J, He X.

J Biol Chem. 2007 May 25;282(21):15903-11. Epub 2007 Mar 30.

8.

Identification and characterization of Wnt signaling pathway in keloid pathogenesis.

Igota S, Tosa M, Murakami M, Egawa S, Shimizu H, Hyakusoku H, Ghazizadeh M.

Int J Med Sci. 2013;10(4):344-54. doi: 10.7150/ijms.5349. Epub 2013 Feb 15.

9.

New insights into the mechanism of Wnt signaling pathway activation.

Kikuchi A, Yamamoto H, Sato A, Matsumoto S.

Int Rev Cell Mol Biol. 2011;291:21-71. doi: 10.1016/B978-0-12-386035-4.00002-1. Review.

PMID:
22017973
10.

Syndecan-4 inhibits Wnt/β-catenin signaling through regulation of low-density-lipoprotein receptor-related protein (LRP6) and R-spondin 3.

Astudillo P, Carrasco H, Larraín J.

Int J Biochem Cell Biol. 2014 Jan;46:103-12. doi: 10.1016/j.biocel.2013.11.012. Epub 2013 Nov 23.

PMID:
24275095
11.

Expression of the novel Wnt receptor ROR2 is increased in breast cancer and may regulate both β-catenin dependent and independent Wnt signalling.

Henry C, Quadir A, Hawkins NJ, Jary E, Llamosas E, Kumar D, Daniels B, Ward RL, Ford CE.

J Cancer Res Clin Oncol. 2015 Feb;141(2):243-54. doi: 10.1007/s00432-014-1824-y. Epub 2014 Sep 11.

PMID:
25209439
12.
13.

An orphan nuclear receptor finds a home.

Kimmel AR.

Mol Cell. 2010 Jan 29;37(2):155-7. doi: 10.1016/j.molcel.2010.01.008.

14.

A critical role for endocytosis in Wnt signaling.

Blitzer JT, Nusse R.

BMC Cell Biol. 2006 Jul 6;7:28.

15.

Functional Crosstalk Between WNT Signaling and Tyrosine Kinase Signaling in Cancer.

Anastas JN.

Semin Oncol. 2015 Dec;42(6):820-31. doi: 10.1053/j.seminoncol.2015.09.020. Epub 2015 Sep 21. Review.

PMID:
26615128
16.

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling.

Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius H, Hoppe D, Stannek P, Walter C, Glinka A, Niehrs C.

Nature. 2002 Jun 6;417(6889):664-7. Epub 2002 May 26.

PMID:
12050670
17.

A finger on the pulse of Wnt receptor signaling.

MacDonald BT, He X.

Cell Res. 2012 Oct;22(10):1410-2. doi: 10.1038/cr.2012.91. Epub 2012 Jun 12.

18.

Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling.

Sakane H, Yamamoto H, Matsumoto S, Sato A, Kikuchi A.

J Cell Sci. 2012 Jan 15;125(Pt 2):449-60. doi: 10.1242/jcs.091876. Epub 2012 Feb 2.

19.

Inhibition of endocytosis blocks Wnt signalling to beta-catenin by promoting dishevelled degradation.

Bryja V, Cajánek L, Grahn A, Schulte G.

Acta Physiol (Oxf). 2007 May;190(1):55-61.

PMID:
17428233
20.

The Wnt5a/Ror2 noncanonical signaling pathway inhibits canonical Wnt signaling in K562 cells.

Yuan Y, Niu CC, Deng G, Li ZQ, Pan J, Zhao C, Yang ZL, Si WK.

Int J Mol Med. 2011 Jan;27(1):63-9. doi: 10.3892/ijmm.2010.560. Epub 2010 Nov 10.

PMID:
21069266

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