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Items: 1 to 20 of 193

1.

A quantitative signaling screen identifies CARD11 mutations in the CARD and LATCH domains that induce Bcl10 ubiquitination and human lymphoma cell survival.

Chan W, Schaffer TB, Pomerantz JL.

Mol Cell Biol. 2013 Jan;33(2):429-43. doi: 10.1128/MCB.00850-12. Epub 2012 Nov 12.

3.
4.

Oncogenic CARD11 mutations induce hyperactive signaling by disrupting autoinhibition by the PKC-responsive inhibitory domain.

Lamason RL, McCully RR, Lew SM, Pomerantz JL.

Biochemistry. 2010 Sep 28;49(38):8240-50. doi: 10.1021/bi101052d.

5.

Intramolecular Interactions and Regulation of Cofactor Binding by the Four Repressive Elements in the Caspase Recruitment Domain-containing Protein 11 (CARD11) Inhibitory Domain.

Jattani RP, Tritapoe JM, Pomerantz JL.

J Biol Chem. 2016 Apr 15;291(16):8338-48. doi: 10.1074/jbc.M116.717322. Epub 2016 Feb 16.

6.

Lymphomagenic CARD11/BCL10/MALT1 signaling drives malignant B-cell proliferation via cooperative NF-κB and JNK activation.

Knies N, Alankus B, Weilemann A, Tzankov A, Brunner K, Ruff T, Kremer M, Keller UB, Lenz G, Ruland J.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):E7230-8. doi: 10.1073/pnas.1507459112. Epub 2015 Dec 14.

7.

Psoriasis mutations disrupt CARD14 autoinhibition promoting BCL10-MALT1-dependent NF-κB activation.

Howes A, O'Sullivan PA, Breyer F, Ghose A, Cao L, Krappmann D, Bowcock AM, Ley SC.

Biochem J. 2016 Jun 15;473(12):1759-68. doi: 10.1042/BCJ20160270. Epub 2016 Apr 12.

PMID:
27071417
8.

Cooperative Control of Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling by an Unusual Array of Redundant Repressive Elements.

Jattani RP, Tritapoe JM, Pomerantz JL.

J Biol Chem. 2016 Apr 15;291(16):8324-36. doi: 10.1074/jbc.M115.683714. Epub 2016 Feb 16.

9.

Negative Regulation of CARD11 Signaling and Lymphoma Cell Survival by the E3 Ubiquitin Ligase RNF181.

Pedersen SM, Chan W, Jattani RP, Mackie dS, Pomerantz JL.

Mol Cell Biol. 2015 Dec 28;36(5):794-808. doi: 10.1128/MCB.00876-15. Erratum in: Mol Cell Biol. 2016 Apr;36(8):1322.

10.

Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival.

Bidère N, Ngo VN, Lee J, Collins C, Zheng L, Wan F, Davis RE, Lenz G, Anderson DE, Arnoult D, Vazquez A, Sakai K, Zhang J, Meng Z, Veenstra TD, Staudt LM, Lenardo MJ.

Nature. 2009 Mar 5;458(7234):92-6. doi: 10.1038/nature07613. Epub 2008 Dec 31.

11.

Trimeric G protein-CARMA1 axis links smoothened, the hedgehog receptor transducer, to NF-κB activation in diffuse large B-cell lymphoma.

Qu C, Liu Y, Kunkalla K, Singh RR, Blonska M, Lin X, Agarwal NK, Vega F.

Blood. 2013 Jun 6;121(23):4718-28. doi: 10.1182/blood-2012-12-470153. Epub 2013 Apr 30.

12.

CARD11 and CARD14 are novel caspase recruitment domain (CARD)/membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B.

Bertin J, Wang L, Guo Y, Jacobson MD, Poyet JL, Srinivasula SM, Merriam S, DiStefano PS, Alnemri ES.

J Biol Chem. 2001 Apr 13;276(15):11877-82. Epub 2001 Jan 12.

13.

Protein kinase C-δ negatively regulates T cell receptor-induced NF-κB activation by inhibiting the assembly of CARMA1 signalosome.

Liu Y, Song R, Gao Y, Li Y, Wang S, Liu HY, Wang Y, Hu YH, Shu HB.

J Biol Chem. 2012 Jun 8;287(24):20081-7. doi: 10.1074/jbc.M111.335463. Epub 2012 Apr 23.

14.

Molecular pathways: targeting MALT1 paracaspase activity in lymphoma.

Fontán L, Melnick A.

Clin Cancer Res. 2013 Dec 15;19(24):6662-8. doi: 10.1158/1078-0432.CCR-12-3869. Epub 2013 Sep 4. Review.

15.

PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation.

Lee KY, D'Acquisto F, Hayden MS, Shim JH, Ghosh S.

Science. 2005 Apr 1;308(5718):114-8.

16.

Genetic errors of the human caspase recruitment domain-B-cell lymphoma 10-mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex: Molecular, immunologic, and clinical heterogeneity.

Pérez de Diego R, Sánchez-Ramón S, López-Collazo E, Martínez-Barricarte R, Cubillos-Zapata C, Ferreira Cerdán A, Casanova JL, Puel A.

J Allergy Clin Immunol. 2015 Nov;136(5):1139-49. doi: 10.1016/j.jaci.2015.06.031. Epub 2015 Aug 12. Review.

17.

Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-κB activation.

Moreno-García ME, Sommer K, Rincon-Arano H, Brault M, Ninomiya-Tsuji J, Matesic LE, Rawlings DJ.

Mol Cell Biol. 2013 Mar;33(6):1149-63. doi: 10.1128/MCB.06407-11. Epub 2013 Jan 7.

18.

The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiency.

Turvey SE, Durandy A, Fischer A, Fung SY, Geha RS, Gewies A, Giese T, Greil J, Keller B, McKinnon ML, Neven B, Rozmus J, Ruland J, Snow AL, Stepensky P, Warnatz K.

J Allergy Clin Immunol. 2014 Aug;134(2):276-84. doi: 10.1016/j.jaci.2014.06.015. Review.

19.

Targeting Non-proteolytic Protein Ubiquitination for the Treatment of Diffuse Large B Cell Lymphoma.

Yang Y, Kelly P, Shaffer AL 3rd, Schmitz R, Yoo HM, Liu X, Huang DW, Webster D, Young RM, Nakagawa M, Ceribelli M, Wright GW, Yang Y, Zhao H, Yu X, Xu W, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Delabie J, Rimsza L, Staudt LM.

Cancer Cell. 2016 Apr 11;29(4):494-507. doi: 10.1016/j.ccell.2016.03.006.

20.

Oncogenic CARD11 mutations in human diffuse large B cell lymphoma.

Lenz G, Davis RE, Ngo VN, Lam L, George TC, Wright GW, Dave SS, Zhao H, Xu W, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Connors JM, Rimsza LM, Campo E, Jaffe ES, Delabie J, Smeland EB, Fisher RI, Chan WC, Staudt LM.

Science. 2008 Mar 21;319(5870):1676-9. doi: 10.1126/science.1153629. Epub 2008 Mar 6.

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