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Items: 1 to 20 of 75

1.

Vascular Gas6 contributes to thrombogenesis and promotes tissue factor up-regulation after vessel injury in mice.

Robins RS, Lemarié CA, Laurance S, Aghourian MN, Wu J, Blostein MD.

Blood. 2013 Jan 24;121(4):692-9. doi: 10.1182/blood-2012-05-433730.

2.

Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall.

Day SM, Reeve JL, Pedersen B, Farris DM, Myers DD, Im M, Wakefield TW, Mackman N, Fay WP.

Blood. 2005 Jan 1;105(1):192-8.

3.

Role of the growth arrest-specific gene 6 (gas6) product in thrombus stabilization.

Saller F, Burnier L, Schapira M, Angelillo-Scherrer A.

Blood Cells Mol Dis. 2006 May-Jun;36(3):373-8. Review.

PMID:
16564713
4.

Tissue factor-positive neutrophils bind to injured endothelial wall and initiate thrombus formation.

Darbousset R, Thomas GM, Mezouar S, Frère C, Bonier R, Mackman N, Renné T, Dignat-George F, Dubois C, Panicot-Dubois L.

Blood. 2012 Sep 6;120(10):2133-43. doi: 10.1182/blood-2012-06-437772.

5.

Endothelial cells but not platelets are the major source of Toll-like receptor 4 in the arterial thrombosis and tissue factor expression in mice.

Ren M, Li R, Luo M, Chen N, Deng X, Yan K, Zeng M, Wu J.

Am J Physiol Regul Integr Comp Physiol. 2014 Oct 1;307(7):R901-7. doi: 10.1152/ajpregu.00324.2014.

6.

Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.

Angelillo-Scherrer A, de Frutos P, Aparicio C, Melis E, Savi P, Lupu F, Arnout J, Dewerchin M, Hoylaerts M, Herbert J, Collen D, Dahlbäck B, Carmeliet P.

Nat Med. 2001 Feb;7(2):215-21.

PMID:
11175853
7.

Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation.

Chou J, Mackman N, Merrill-Skoloff G, Pedersen B, Furie BC, Furie B.

Blood. 2004 Nov 15;104(10):3190-7.

8.

Growth arrest-specific 6 regulates thrombin-induced expression of vascular cell adhesion molecule-1 through forkhead box O1 in endothelial cells.

Bertin FR, Lemarié CA, Robins RS, Blostein MD.

J Thromb Haemost. 2015 Dec;13(12):2260-72. doi: 10.1111/jth.13156.

PMID:
26414399
9.

Key role of platelet procoagulant activity in tissue factor-and collagen-dependent thrombus formation in arterioles and venules in vivo differential sensitivity to thrombin inhibition.

Kuijpers MJ, Munnix IC, Cosemans JM, Vlijmen BV, Reutelingsperger CP, Egbrink MO, Heemskerk JW.

Microcirculation. 2008 May;15(4):269-82. doi: 10.1080/10739680701653517.

PMID:
18464157
10.

Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy.

Angelillo-Scherrer A, Burnier L, Flores N, Savi P, DeMol M, Schaeffer P, Herbert JM, Lemke G, Goff SP, Matsushima GK, Earp HS, Vesin C, Hoylaerts MF, Plaisance S, Collen D, Conway EM, Wehrle-Haller B, Carmeliet P.

J Clin Invest. 2005 Feb;115(2):237-46.

11.

Prostaglandin E synthase is upregulated by Gas6 during cancer-induced venous thrombosis.

Aghourian MN, Lemarié CA, Bertin FR, Blostein MD.

Blood. 2016 Feb 11;127(6):769-77. doi: 10.1182/blood-2015-02-628867.

PMID:
26585956
12.

Growth arrest specific gene (GAS) 6 modulates platelet thrombus formation and vascular wall homeostasis and represents an attractive drug target.

Maree AO, Jneid H, Palacios IF, Rosenfield K, MacRae CA, Fitzgerald DJ.

Curr Pharm Des. 2007;13(26):2656-61. Review.

PMID:
17897008
13.

Growth arrest-specific gene 6 (gas6) and vascular hemostasis.

Laurance S, Lemarié CA, Blostein MD.

Adv Nutr. 2012 Mar 1;3(2):196-203. doi: 10.3945/an.111.001826. Review.

14.

Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.

Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Hervé C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, García de Frutos P, Dahlbäck B, Carmeliet P, Hoylaerts MF, Moons L.

Blood. 2008 Apr 15;111(8):4096-105.

15.

Gas6 gains entry into the coagulation cascade.

Foley JH, Conway EM.

Blood. 2013 Jan 24;121(4):570-1. doi: 10.1182/blood-2012-11-468678. No abstract available.

16.

Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization.

Cosemans JM, Van Kruchten R, Olieslagers S, Schurgers LJ, Verheyen FK, Munnix IC, Waltenberger J, Angelillo-Scherrer A, Hoylaerts MF, Carmeliet P, Heemskerk JW.

J Thromb Haemost. 2010 Aug;8(8):1797-808. doi: 10.1111/j.1538-7836.2010.03935.x.

17.

Pleiotropic role of growth arrest-specific gene 6 in atherosclerosis.

Tjwa M, Moons L, Lutgens E.

Curr Opin Lipidol. 2009 Oct;20(5):386-92. doi: 10.1097/MOL.0b013e328330982e. Review.

PMID:
19644365
18.

PECAM-1 modulates thrombin-induced tissue factor expression on endothelial cells.

Zhang JJ, Kelm RJ, Biswas P, Kashgarian M, Madri JA.

J Cell Physiol. 2007 Feb;210(2):527-37.

PMID:
17111362
19.

Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse.

Falati S, Gross P, Merrill-Skoloff G, Furie BC, Furie B.

Nat Med. 2002 Oct;8(10):1175-81.

PMID:
12244306
20.

Leukocyte-versus microparticle-mediated tissue factor transfer during arteriolar thrombus development.

Gross PL, Furie BC, Merrill-Skoloff G, Chou J, Furie B.

J Leukoc Biol. 2005 Dec;78(6):1318-26.

PMID:
16204641
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