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Items: 1 to 20 of 126

1.

ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.

Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, Thomas-Tikhonenko A, Perl AE, Koong A, Fuchs SY, Diehl JA, Mills IG, Ruggero D, Koumenis C.

J Clin Invest. 2012 Dec;122(12):4621-34. doi: 10.1172/JCI62973. Epub 2012 Nov 12.

2.

PERK-ing up autophagy during MYC-induced tumorigenesis.

Dey S, Tameire F, Koumenis C.

Autophagy. 2013 Apr;9(4):612-4. doi: 10.4161/auto.23486. Epub 2013 Jan 17.

3.

Myc-driven overgrowth requires unfolded protein response-mediated induction of autophagy and antioxidant responses in Drosophila melanogaster.

Nagy P, Varga A, Pircs K, Hegedűs K, Juhász G.

PLoS Genet. 2013;9(8):e1003664. doi: 10.1371/journal.pgen.1003664. Epub 2013 Aug 8.

4.

The IKK2/NF-{kappa}B pathway suppresses MYC-induced lymphomagenesis.

Klapproth K, Sander S, Marinkovic D, Baumann B, Wirth T.

Blood. 2009 Sep 17;114(12):2448-58. doi: 10.1182/blood-2008-09-181008. Epub 2009 Jul 23.

5.

Disruption of the ribosomal P complex leads to stress-induced autophagy.

Artero-Castro A, Perez-Alea M, Feliciano A, Leal JA, Genestar M, Castellvi J, Peg V, Ramón Y Cajal S, Lleonart ME.

Autophagy. 2015;11(9):1499-519. doi: 10.1080/15548627.2015.1063764.

6.

Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis.

Maclean KH, Dorsey FC, Cleveland JL, Kastan MB.

J Clin Invest. 2008 Jan;118(1):79-88. Erratum in: J Clin Invest. 2008 Apr;118(4):1584.

7.

The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells.

Sahni S, Bae DH, Lane DJ, Kovacevic Z, Kalinowski DS, Jansson PJ, Richardson DR.

J Biol Chem. 2014 Apr 4;289(14):9692-709. doi: 10.1074/jbc.M113.529511. Epub 2014 Feb 15.

8.

MYC regulates the unfolded protein response and glucose and glutamine uptake in endocrine resistant breast cancer.

Shajahan-Haq AN, Cook KL, Schwartz-Roberts JL, Eltayeb AE, Demas DM, Warri AM, Facey CO, Hilakivi-Clarke LA, Clarke R.

Mol Cancer. 2014 Oct 23;13:239. doi: 10.1186/1476-4598-13-239.

9.

Lipopolysaccharide Induces Autophagic Cell Death through the PERK-Dependent Branch of the Unfolded Protein Response in Human Alveolar Epithelial A549 Cells.

Li S, Guo L, Qian P, Zhao Y, Liu A, Ji F, Chen L, Wu X, Qian G.

Cell Physiol Biochem. 2015;36(6):2403-17. doi: 10.1159/000430202. Epub 2015 Jul 27.

10.

Mammalian target of rapamycin complex 1 (mTORC1) enhances bortezomib-induced death in tuberous sclerosis complex (TSC)-null cells by a c-MYC-dependent induction of the unfolded protein response.

Babcock JT, Nguyen HB, He Y, Hendricks JW, Wek RC, Quilliam LA.

J Biol Chem. 2013 May 31;288(22):15687-98. doi: 10.1074/jbc.M112.431056. Epub 2013 Apr 23.

11.

Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy.

Vandewynckel YP, Laukens D, Bogaerts E, Paridaens A, Van den Bussche A, Verhelst X, Van Steenkiste C, Descamps B, Vanhove C, Libbrecht L, De Rycke R, Lambrecht BN, Geerts A, Janssens S, Van Vlierberghe H.

Hepatol Int. 2014 Oct 1;9(1):93-104. doi: 10.1007/s12072-014-9582-0. eCollection 2015 Jan.

12.

Activation of ER stress and apoptosis by hydrogen peroxide in HeLa cells: protective role of mild heat preconditioning at 40°C.

Pallepati P, Averill-Bates DA.

Biochim Biophys Acta. 2011 Dec;1813(12):1987-99. doi: 10.1016/j.bbamcr.2011.07.021. Epub 2011 Aug 22.

13.

Ras inhibits endoplasmic reticulum stress in human cancer cells with amplified Myc.

Yaari-Stark S, Shaked M, Nevo-Caspi Y, Jacob-Hircsh J, Shamir R, Rechavi G, Kloog Y.

Int J Cancer. 2010 May 15;126(10):2268-81. doi: 10.1002/ijc.25102.

14.

A close connection between the PERK and IRE arms of the UPR and the transcriptional regulation of autophagy.

Deegan S, Koryga I, Glynn SA, Gupta S, Gorman AM, Samali A.

Biochem Biophys Res Commun. 2015 Jan 2;456(1):305-11. doi: 10.1016/j.bbrc.2014.11.076. Epub 2014 Dec 2.

PMID:
25475719
15.

The involvement of endoplasmic reticulum stress in the suppression of colorectal tumorigenesis by tolfenamic acid.

Zhang X, Lee SH, Min KW, McEntee MF, Jeong JB, Li Q, Baek SJ.

Cancer Prev Res (Phila). 2013 Dec;6(12):1337-47. doi: 10.1158/1940-6207.CAPR-13-0220. Epub 2013 Oct 8.

16.

Antimalarial therapy prevents Myc-induced lymphoma.

Dang CV.

J Clin Invest. 2008 Jan;118(1):15-7.

17.

Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches determine cell survival.

Walter F, Schmid J, Düssmann H, Concannon CG, Prehn JH.

Cell Death Differ. 2015 Sep;22(9):1502-16. doi: 10.1038/cdd.2014.241. Epub 2015 Jan 30.

18.

Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.

Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, Cavener DR, Imaizumi K.

J Biol Chem. 2011 Feb 11;286(6):4809-18. doi: 10.1074/jbc.M110.152900. Epub 2010 Dec 6.

19.
20.

Endoplasmic reticulum stress-mediated autophagy contributes to bluetongue virus infection via the PERK-eIF2α pathway.

Lv S, Sun EC, Xu QY, Zhang JK, Wu DL.

Biochem Biophys Res Commun. 2015 Oct 23;466(3):406-12. doi: 10.1016/j.bbrc.2015.09.039. Epub 2015 Sep 10.

PMID:
26363458

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