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Items: 1 to 20 of 147


Mediator phosphorylation prevents stress response transcription during non-stress conditions.

Miller C, Matic I, Maier KC, Schwalb B, Roether S, Strässer K, Tresch A, Mann M, Cramer P.

J Biol Chem. 2012 Dec 28;287(53):44017-26. doi: 10.1074/jbc.M112.430140. Epub 2012 Nov 7.


Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16.

Kim S, Gross DS.

J Biol Chem. 2013 Apr 26;288(17):12197-213. doi: 10.1074/jbc.M112.449553. Epub 2013 Feb 27.


Direct interaction of RNA polymerase II and mediator required for transcription in vivo.

Soutourina J, Wydau S, Ambroise Y, Boschiero C, Werner M.

Science. 2011 Mar 18;331(6023):1451-4. doi: 10.1126/science.1200188.


Role of Mediator in regulating Pol II elongation and nucleosome displacement in Saccharomyces cerevisiae.

Kremer SB, Kim S, Jeon JO, Moustafa YW, Chen A, Zhao J, Gross DS.

Genetics. 2012 May;191(1):95-106. doi: 10.1534/genetics.111.135806. Epub 2012 Feb 29.


Origins and activity of the Mediator complex.

Conaway RC, Conaway JW.

Semin Cell Dev Biol. 2011 Sep;22(7):729-34. doi: 10.1016/j.semcdb.2011.07.021. Epub 2011 Jul 28. Review.


Novel role for mediator complex subunit Srb5/Med18 in termination of transcription.

Mukundan B, Ansari A.

J Biol Chem. 2011 Oct 28;286(43):37053-7. doi: 10.1074/jbc.C111.295915. Epub 2011 Sep 14.


Selective role of Mediator tail module in the transcription of highly regulated genes in yeast.

Ansari SA, Morse RH.

Transcription. 2012 May-Jun;3(3):110-4. doi: 10.4161/trns.19840.


The yeast Mediator complex and its regulation.

Björklund S, Gustafsson CM.

Trends Biochem Sci. 2005 May;30(5):240-4. Review.


Genome-wide association of mediator and RNA polymerase II in wild-type and mediator mutant yeast.

Paul E, Zhu ZI, Landsman D, Morse RH.

Mol Cell Biol. 2015 Jan;35(1):331-42. doi: 10.1128/MCB.00991-14. Epub 2014 Nov 3.


Role of Gal11, a component of the RNA polymerase II mediator in stress-induced hyperphosphorylation of Msn2 in Saccharomyces cerevisiae.

Lallet S, Garreau H, Garmendia-Torres C, Szestakowska D, Boy-Marcotte E, Quevillon-Chéruel S, Jacquet M.

Mol Microbiol. 2006 Oct;62(2):438-52.


Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme.

Sato S, Tomomori-Sato C, Tsai KL, Yu X, Sardiu M, Saraf A, Washburn MP, Florens L, Asturias FJ, Conaway RC, Conaway JW.

J Biol Chem. 2016 Dec 23;291(52):26886-26898. doi: 10.1074/jbc.M116.756098. Epub 2016 Nov 7.


Distinct role of Mediator tail module in regulation of SAGA-dependent, TATA-containing genes in yeast.

Ansari SA, Ganapathi M, Benschop JJ, Holstege FC, Wade JT, Morse RH.

EMBO J. 2012 Jan 4;31(1):44-57. doi: 10.1038/emboj.2011.362. Epub 2011 Oct 4.


Activator Gcn4 employs multiple segments of Med15/Gal11, including the KIX domain, to recruit mediator to target genes in vivo.

Jedidi I, Zhang F, Qiu H, Stahl SJ, Palmer I, Kaufman JD, Nadaud PS, Mukherjee S, Wingfield PT, Jaroniec CP, Hinnebusch AG.

J Biol Chem. 2010 Jan 22;285(4):2438-55. doi: 10.1074/jbc.M109.071589. Epub 2009 Nov 23.


Site-specific Srb10-dependent phosphorylation of the yeast Mediator subunit Med2 regulates gene expression from the 2-microm plasmid.

Hallberg M, Polozkov GV, Hu GZ, Beve J, Gustafsson CM, Ronne H, Björklund S.

Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3370-5. Epub 2004 Feb 26.


Med19(Rox3) regulates Intermodule interactions in the Saccharomyces cerevisiae mediator complex.

Baidoobonso SM, Guidi BW, Myers LC.

J Biol Chem. 2007 Feb 23;282(8):5551-9. Epub 2006 Dec 27.


Mediator as a general transcription factor.

Takagi Y, Kornberg RD.

J Biol Chem. 2006 Jan 6;281(1):80-9. Epub 2005 Nov 1.


Preponderance of free mediator in the yeast Saccharomyces cerevisiae.

Takagi Y, Chadick JZ, Davis JA, Asturias FJ.

J Biol Chem. 2005 Sep 2;280(35):31200-7. Epub 2005 Jul 6.


Mediator expression profiling epistasis reveals a signal transduction pathway with antagonistic submodules and highly specific downstream targets.

van de Peppel J, Kettelarij N, van Bakel H, Kockelkorn TT, van Leenen D, Holstege FC.

Mol Cell. 2005 Aug 19;19(4):511-22.


A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction.

Tsai KL, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Asturias FJ.

Nat Struct Mol Biol. 2013 May;20(5):611-9. doi: 10.1038/nsmb.2549. Epub 2013 Apr 7.

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