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Items: 1 to 20 of 196

1.

mTOR-dependent cell survival mechanisms.

Hung CM, Garcia-Haro L, Sparks CA, Guertin DA.

Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12). pii: a008771. doi: 10.1101/cshperspect.a008771. Review.

2.

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.

Shaw RJ.

Acta Physiol (Oxf). 2009 May;196(1):65-80. doi: 10.1111/j.1748-1716.2009.01972.x. Epub 2009 Feb 19. Review.

3.

Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.

Jhanwar-Uniyal M, Gillick JL, Neil J, Tobias M, Thwing ZE, Murali R.

Adv Biol Regul. 2015 Jan;57:64-74. doi: 10.1016/j.jbior.2014.09.004. Epub 2014 Sep 18.

PMID:
25442674
4.

Growing knowledge of the mTOR signaling network.

Huang K, Fingar DC.

Semin Cell Dev Biol. 2014 Dec;36:79-90. doi: 10.1016/j.semcdb.2014.09.011. Epub 2014 Sep 19. Review.

5.

Nutrient regulation of the mTOR complex 1 signaling pathway.

Kim SG, Buel GR, Blenis J.

Mol Cells. 2013 Jun;35(6):463-73. doi: 10.1007/s10059-013-0138-2. Epub 2013 May 20. Review.

6.

The expanding role of mTOR in cancer cell growth and proliferation.

Cargnello M, Tcherkezian J, Roux PP.

Mutagenesis. 2015 Mar;30(2):169-76. doi: 10.1093/mutage/geu045. Review.

PMID:
25688110
7.

Targeted Inhibition of Rictor/mTORC2 in Cancer Treatment: A New Era after Rapamycin.

Zou Z, Chen J, Yang J, Bai X.

Curr Cancer Drug Targets. 2016;16(4):288-304. Review.

PMID:
26563881
8.

Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival.

Ma S, Venkatesh A, Langellotto F, Le YZ, Hall MN, Rüegg MA, Punzo C.

Exp Eye Res. 2015 Jun;135:1-13. doi: 10.1016/j.exer.2015.04.006. Epub 2015 Apr 14.

9.

RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.

Gordon BS, Kazi AA, Coleman CS, Dennis MD, Chau V, Jefferson LS, Kimball SR.

Cell Signal. 2014 Mar;26(3):461-7. doi: 10.1016/j.cellsig.2013.11.035. Epub 2013 Dec 3.

10.

Spatial regulation of the mTORC1 system in amino acids sensing pathway.

Suzuki T, Inoki K.

Acta Biochim Biophys Sin (Shanghai). 2011 Sep;43(9):671-9. doi: 10.1093/abbs/gmr066. Epub 2011 Jul 23. Review.

11.

Autoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanism.

Chen CH, Kiyan V, Zhylkibayev AA, Kazyken D, Bulgakova O, Page KE, Bersimbaev RI, Spooner E, Sarbassov dos D.

J Biol Chem. 2013 Sep 20;288(38):27019-30. doi: 10.1074/jbc.M113.498055. Epub 2013 Aug 8.

12.

Therapeutic targeting of the mTOR-signalling pathway in cancer: benefits and limitations.

Moschetta M, Reale A, Marasco C, Vacca A, Carratù MR.

Br J Pharmacol. 2014 Aug;171(16):3801-13. doi: 10.1111/bph.12749. Review.

13.

Mammalian target of rapamycin and the kidney. I. The signaling pathway.

Lieberthal W, Levine JS.

Am J Physiol Renal Physiol. 2012 Jul 1;303(1):F1-10. doi: 10.1152/ajprenal.00014.2012. Epub 2012 Mar 14. Review.

PMID:
22419691
14.

Nutrient signaling to mTOR and cell growth.

Jewell JL, Guan KL.

Trends Biochem Sci. 2013 May;38(5):233-42. doi: 10.1016/j.tibs.2013.01.004. Epub 2013 Mar 1. Review.

15.
16.

Distinct inhibitory effects on mTOR signaling by ethanol and INK128 in diffuse large B-cell lymphoma.

Mazan-Mamczarz K, Peroutka RJ, Steinhardt JJ, Gidoni M, Zhang Y, Lehrmann E, Landon AL, Dai B, Houng S, Muniandy PA, Efroni S, Becker KG, Gartenhaus RB.

Cell Commun Signal. 2015 Mar 1;13:15. doi: 10.1186/s12964-015-0091-0.

17.

mTOR and autophagy: a dynamic relationship governed by nutrients and energy.

Dunlop EA, Tee AR.

Semin Cell Dev Biol. 2014 Dec;36:121-9. doi: 10.1016/j.semcdb.2014.08.006. Epub 2014 Aug 23. Review.

PMID:
25158238
18.

Simultaneous inhibition of mTORC1 and mTORC2 by mTOR kinase inhibitor AZD8055 induces autophagy and cell death in cancer cells.

Sini P, James D, Chresta C, Guichard S.

Autophagy. 2010 May;6(4):553-4. doi: 10.4161/auto.6.4.11671. Epub 2010 May 16.

PMID:
20364113
19.

The mTOR signalling pathway in human cancer.

Pópulo H, Lopes JM, Soares P.

Int J Mol Sci. 2012;13(2):1886-918. doi: 10.3390/ijms13021886. Epub 2012 Feb 10. Review.

20.

mTORC1 signaling and the metabolic control of cell growth.

Ben-Sahra I, Manning BD.

Curr Opin Cell Biol. 2017 Apr;45:72-82. doi: 10.1016/j.ceb.2017.02.012. Epub 2017 Apr 12. Review.

PMID:
28411448

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