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Items: 1 to 20 of 365

1.

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.

Mitra D, Luo X, Morgan A, Wang J, Hoang MP, Lo J, Guerrero CR, Lennerz JK, Mihm MC, Wargo JA, Robinson KC, Devi SP, Vanover JC, D'Orazio JA, McMahon M, Bosenberg MW, Haigis KM, Haber DA, Wang Y, Fisher DE.

Nature. 2012 Nov 15;491(7424):449-53. doi: 10.1038/nature11624. Epub 2012 Oct 31.

2.

MC1R and the response of melanocytes to ultraviolet radiation.

Rouzaud F, Kadekaro AL, Abdel-Malek ZA, Hearing VJ.

Mutat Res. 2005 Apr 1;571(1-2):133-52. Epub 2005 Jan 26. Review.

PMID:
15748644
3.

The eumelanin and pheomelanin contents in dorsal hairs of female recessive yellow mice are greater than in male.

Hirobe T, Wakamatsu K, Ito S.

J Dermatol Sci. 2007 Jan;45(1):55-62. Epub 2006 Nov 22.

PMID:
17123789
4.

Melanocortins and the melanocortin 1 receptor, moving translationally towards melanoma prevention.

Abdel-Malek ZA, Swope VB, Starner RJ, Koikov L, Cassidy P, Leachman S.

Arch Biochem Biophys. 2014 Dec 1;563:4-12. doi: 10.1016/j.abb.2014.07.002. Epub 2014 Jul 11. Review.

PMID:
25017567
5.

A melanin-independent interaction between Mc1r and Met signaling pathways is required for HGF-dependent melanoma.

Wolnicka-Glubisz A, Strickland FM, Wielgus A, Anver M, Merlino G, De Fabo EC, Noonan FP.

Int J Cancer. 2015 Feb 15;136(4):752-60. doi: 10.1002/ijc.29050. Epub 2014 Jul 7.

6.

Melanocortin 1 receptor variants: functional role and pigmentary associations.

Dessinioti C, Antoniou C, Katsambas A, Stratigos AJ.

Photochem Photobiol. 2011 Sep-Oct;87(5):978-87. doi: 10.1111/j.1751-1097.2011.00970.x. Epub 2011 Aug 17. Review.

PMID:
21749400
7.

Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color.

Kennedy C, ter Huurne J, Berkhout M, Gruis N, Bastiaens M, Bergman W, Willemze R, Bavinck JN.

J Invest Dermatol. 2001 Aug;117(2):294-300.

8.

Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation.

Scott MC, Wakamatsu K, Ito S, Kadekaro AL, Kobayashi N, Groden J, Kavanagh R, Takakuwa T, Virador V, Hearing VJ, Abdel-Malek ZA.

J Cell Sci. 2002 Jun 1;115(Pt 11):2349-55.

9.

Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans.

Valverde P, Healy E, Jackson I, Rees JL, Thody AJ.

Nat Genet. 1995 Nov;11(3):328-30.

PMID:
7581459
10.

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation.

García-Borrón JC, Abdel-Malek Z, Jiménez-Cervantes C.

Pigment Cell Melanoma Res. 2014 Sep;27(5):699-720. doi: 10.1111/pcmr.12257. Epub 2014 May 30. Review.

11.

Variants of the melanocortin-1 receptor: do they matter clinically?

Haddadeen C, Lai C, Cho SY, Healy E.

Exp Dermatol. 2015 Jan;24(1):5-9. doi: 10.1111/exd.12540. Epub 2014 Nov 11.

PMID:
25219681
12.

MC1R variants increase risk of melanomas harboring BRAF mutations.

Fargnoli MC, Pike K, Pfeiffer RM, Tsang S, Rozenblum E, Munroe DJ, Golubeva Y, Calista D, Seidenari S, Massi D, Carli P, Bauer J, Elder DE, Bastian BC, Peris K, Landi MT.

J Invest Dermatol. 2008 Oct;128(10):2485-90. doi: 10.1038/jid.2008.67. Epub 2008 Mar 27. Erratum in: J Invest Dermatol. 2008 Oct;128(10):2546. Fargnoli, Maria Concetia [corrected to Fargnoli, Maria Concetta].

13.

[Secrets of the red-headed].

Zdrojewicz Z, Kowalik M, Jagodziński A.

Pol Merkur Lekarski. 2016 Dec 22;41(246):306-309. Review. Polish.

PMID:
28024137
14.

Dominant Red Coat Color in Holstein Cattle Is Associated with a Missense Mutation in the Coatomer Protein Complex, Subunit Alpha (COPA) Gene.

Dorshorst B, Henegar C, Liao X, Sällman Almén M, Rubin CJ, Ito S, Wakamatsu K, Stothard P, Van Doormaal B, Plastow G, Barsh GS, Andersson L.

PLoS One. 2015 Jun 4;10(6):e0128969. doi: 10.1371/journal.pone.0128969. eCollection 2015.

15.
16.

Interaction between p53 codon 72 polymorphism and melanocortin 1 receptor variants on suntan response and cutaneous melanoma risk.

Nan H, Qureshi AA, Hunter DJ, Han J.

Br J Dermatol. 2008 Aug;159(2):314-21. doi: 10.1111/j.1365-2133.2008.08624.x. Epub 2008 May 28.

17.

Melanocortin 1 receptor (MC1R) genotype influences erythemal sensitivity to psoralen-ultraviolet A photochemotherapy.

Smith G, Wilkie MJ, Deeni YY, Farr PM, Ferguson J, Wolf CR, Ibbotson SH.

Br J Dermatol. 2007 Dec;157(6):1230-4. Epub 2007 Oct 4.

PMID:
17916200
18.

Red hair is the null phenotype of MC1R.

Beaumont KA, Shekar SN, Cook AL, Duffy DL, Sturm RA.

Hum Mutat. 2008 Aug;29(8):E88-94. doi: 10.1002/humu.20788.

PMID:
18484624
19.

Melanocortin-1 receptor gene variants determine the risk of nonmelanoma skin cancer independently of fair skin and red hair.

Bastiaens MT, ter Huurne JA, Kielich C, Gruis NA, Westendorp RG, Vermeer BJ, Bavinck JN; Leiden Skin Cancer Study Team.

Am J Hum Genet. 2001 Apr;68(4):884-94. Epub 2001 Mar 16.

20.

Independent regulation of hair and skin color by two G protein-coupled pathways.

Van Raamsdonk CD, Barsh GS, Wakamatsu K, Ito S.

Pigment Cell Melanoma Res. 2009 Dec;22(6):819-26. doi: 10.1111/j.1755-148X.2009.00609.x. Epub 2009 Jul 21.

PMID:
19627560

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