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Items: 1 to 20 of 158

1.

Oridonin: targeting programmed cell death pathways as an anti-tumour agent.

Liu Z, Ouyang L, Peng H, Zhang WZ.

Cell Prolif. 2012 Dec;45(6):499-507. doi: 10.1111/j.1365-2184.2012.00849.x. Review.

PMID:
23106297
2.

Oridonin: An active diterpenoid targeting cell cycle arrest, apoptotic and autophagic pathways for cancer therapeutics.

Li CY, Wang EQ, Cheng Y, Bao JK.

Int J Biochem Cell Biol. 2011 May;43(5):701-4. doi: 10.1016/j.biocel.2011.01.020. Review.

PMID:
21295154
3.

Hydroxyl radical (·OH) played a pivotal role in oridonin-induced apoptosis and autophagy in human epidermoid carcinoma A431 cells.

Yu Y, Fan SM, Song JK, Tashiro S, Onodera S, Ikejima T.

Biol Pharm Bull. 2012;35(12):2148-59.

4.

[Mechanism of downregulation of apoptosis by autophagy induced by oridonin in HeLa cells].

Cui Q, Tashiro S, Onodera S, Ikejima T.

Yao Xue Xue Bao. 2007 Jan;42(1):35-9. Chinese.

PMID:
17520804
5.

Recent advances in the molecular basis of anti-neoplastic mechanisms of oridonin.

Tian W, Chen SY.

Chin J Integr Med. 2013 Apr;19(4):315-20. doi: 10.1007/s11655-013-1437-3. Review.

PMID:
23546635
6.

Ent-kaurane diterpenoids from Rabdosia rubescens and their cytotoxic effects on human cancer cell lines.

Bai N, He K, Zhou Z, Tsai ML, Zhang L, Quan Z, Shao X, Pan MH, Ho CT.

Planta Med. 2010 Feb;76(2):140-5. doi: 10.1055/s-0029-1186002.

PMID:
19653147
7.

Reactive oxygen species contribute to oridonin-induced apoptosis and autophagy in human cervical carcinoma HeLa cells.

Zhang YH, Wu YL, Tashiro S, Onodera S, Ikejima T.

Acta Pharmacol Sin. 2011 Oct;32(10):1266-75. doi: 10.1038/aps.2011.92.

8.

Autophagy preceded apoptosis in oridonin-treated human breast cancer MCF-7 cells.

Cui Q, Tashiro S, Onodera S, Minami M, Ikejima T.

Biol Pharm Bull. 2007 May;30(5):859-64.

9.

Oridonin phosphate-induced autophagy effectively enhances cell apoptosis of human breast cancer cells.

Li Y, Wang Y, Wang S, Gao Y, Zhang X, Lu C.

Med Oncol. 2015 Jan;32(1):365. doi: 10.1007/s12032-014-0365-1.

PMID:
25491140
10.

Molecular Insight in the Multifunctional Effects of Oridonin.

Owona BA, Schluesener HJ.

Drugs R D. 2015 Sep;15(3):233-44. doi: 10.1007/s40268-015-0102-z. Review.

11.

Apoptosis-suppressing and autophagy-promoting effects of calpain on oridonin-induced L929 cell death.

Cheng Y, Qiu F, Huang J, Tashiro S, Onodera S, Ikejima T.

Arch Biochem Biophys. 2008 Jul 15;475(2):148-55. doi: 10.1016/j.abb.2008.04.027.

PMID:
18468506
12.

Inhibition of caspase-9 by oridonin, a diterpenoid isolated from Rabdosia rubescens, augments apoptosis in human laryngeal cancer cells.

Kang N, Cao SJ, Zhou Y, He H, Tashiro S, Onodera S, Qiu F, Ikejima T.

Int J Oncol. 2015 Dec;47(6):2045-56. doi: 10.3892/ijo.2015.3186.

13.

Augmentation of oridonin-induced apoptosis observed with reduced autophagy.

Cui Q, Tashiro S, Onodera S, Ikejima T.

J Pharmacol Sci. 2006 Jul;101(3):230-9.

14.

Plant natural compounds: targeting pathways of autophagy as anti-cancer therapeutic agents.

Zhang X, Chen LX, Ouyang L, Cheng Y, Liu B.

Cell Prolif. 2012 Oct;45(5):466-76. doi: 10.1111/j.1365-2184.2012.00833.x. Review.

PMID:
22765290
15.
16.

Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1.

Zeng R, Chen Y, Zhao S, Cui GH.

Acta Pharmacol Sin. 2012 Jan;33(1):91-100. doi: 10.1038/aps.2011.143.

18.

Oridonin, a promising antitumor natural product in the chemotherapy of hematological malignancies.

Zhao Z, Chen Y.

Curr Pharm Biotechnol. 2014;15(11):1083-92. Review.

PMID:
25391243
19.

Back to the future of oridonin: again, compound from medicinal herb shows potent antileukemia efficacies in vitro and in vivo.

Zhou GB, Chen SJ, Wang ZY, Chen Z.

Cell Res. 2007 Apr;17(4):274-6. No abstract available.

20.

The cytostatic and cytotoxic effects of oridonin (Rubescenin), a diterpenoid from Rabdosia rubescens, on tumor cells of different lineage.

Chen S, Gao J, Halicka HD, Huang X, Traganos F, Darzynkiewicz Z.

Int J Oncol. 2005 Mar;26(3):579-88.

PMID:
15703811

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