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Items: 1 to 20 of 208

1.

Genetic association analysis of complex diseases incorporating intermediate phenotype information.

Li Y, Huang J, Amos CI.

PLoS One. 2012;7(10):e46612. doi: 10.1371/journal.pone.0046612. Epub 2012 Oct 19.

2.

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliövaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nöthen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ.

PLoS Genet. 2010 Aug 5;6(8). pii: e1001053. doi: 10.1371/journal.pgen.1001053.

3.

Role of CHRNA5-A3 genetic Locus variants and developing drug for chronic obstructive pulmonary disease.

Lococo F, Cesario A, Petracca-Ciavarella L, Granone P, Russo P.

Curr Med Chem. 2012;19(34):5863-70.

PMID:
23061658
4.

Chromosome 15q25 (CHRNA3-CHRNB4) Variation Indirectly Impacts Lung Cancer Risk in Chinese Males.

Zhang Y, Jiang M, Li Q, Liang W, He Q, Chen W, He J.

PLoS One. 2016 Mar 4;11(3):e0149946. doi: 10.1371/journal.pone.0149946. eCollection 2016.

5.

Nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among African Americans: a case-control study.

Amos CI, Gorlov IP, Dong Q, Wu X, Zhang H, Lu EY, Scheet P, Greisinger AJ, Mills GB, Spitz MR.

J Natl Cancer Inst. 2010 Aug 4;102(15):1199-205. doi: 10.1093/jnci/djq232. Epub 2010 Jun 16.

6.

Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans.

Hansen HM, Xiao Y, Rice T, Bracci PM, Wrensch MR, Sison JD, Chang JS, Smirnov IV, Patoka J, Seldin MF, Quesenberry CP, Kelsey KT, Wiencke JK.

Hum Mol Genet. 2010 Sep 15;19(18):3652-61. doi: 10.1093/hmg/ddq268. Epub 2010 Jun 29.

7.

Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.

Broms U, Wedenoja J, Largeau MR, Korhonen T, Pitkäniemi J, Keskitalo-Vuokko K, Häppölä A, Heikkilä KH, Heikkilä K, Ripatti S, Sarin AP, Salminen O, Paunio T, Pergadia ML, Madden PA, Kaprio J, Loukola A.

Nicotine Tob Res. 2012 Jun;14(6):720-33. doi: 10.1093/ntr/ntr283. Epub 2012 Jan 12.

8.

Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking.

Kapoor M, Wang JC, Bertelsen S, Bucholz K, Budde JP, Hinrichs A, Agrawal A, Brooks A, Chorlian D, Dick D, Hesselbrock V, Foroud T, Kramer J, Kuperman S, Manz N, Nurnberger J Jr, Porjesz B, Rice J, Tischfield J, Xuei X, Schuckit M, Edenberg HJ, Bierut LJ, Goate AM.

PLoS One. 2012;7(3):e33513. doi: 10.1371/journal.pone.0033513. Epub 2012 Mar 16.

9.

Genome-wide meta-analyses of smoking behaviors in African Americans.

David SP, Hamidovic A, Chen GK, Bergen AW, Wessel J, Kasberger JL, Brown WM, Petruzella S, Thacker EL, Kim Y, Nalls MA, Tranah GJ, Sung YJ, Ambrosone CB, Arnett D, Bandera EV, Becker DM, Becker L, Berndt SI, Bernstein L, Blot WJ, Broeckel U, Buxbaum SG, Caporaso N, Casey G, Chanock SJ, Deming SL, Diver WR, Eaton CB, Evans DS, Evans MK, Fornage M, Franceschini N, Harris TB, Henderson BE, Hernandez DG, Hitsman B, Hu JJ, Hunt SC, Ingles SA, John EM, Kittles R, Kolb S, Kolonel LN, Le Marchand L, Liu Y, Lohman KK, McKnight B, Millikan RC, Murphy A, Neslund-Dudas C, Nyante S, Press M, Psaty BM, Rao DC, Redline S, Rodriguez-Gil JL, Rybicki BA, Signorello LB, Singleton AB, Smoller J, Snively B, Spring B, Stanford JL, Strom SS, Swan GE, Taylor KD, Thun MJ, Wilson AF, Witte JS, Yamamura Y, Yanek LR, Yu K, Zheng W, Ziegler RG, Zonderman AB, Jorgenson E, Haiman CA, Furberg H.

Transl Psychiatry. 2012 May 22;2:e119. doi: 10.1038/tp.2012.41.

10.

The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer.

Spitz MR, Amos CI, Dong Q, Lin J, Wu X.

J Natl Cancer Inst. 2008 Nov 5;100(21):1552-6. doi: 10.1093/jnci/djn363. Epub 2008 Oct 28.

11.

The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).

Celedón JC, Lange C, Raby BA, Litonjua AA, Palmer LJ, DeMeo DL, Reilly JJ, Kwiatkowski DJ, Chapman HA, Laird N, Sylvia JS, Hernandez M, Speizer FE, Weiss ST, Silverman EK.

Hum Mol Genet. 2004 Aug 1;13(15):1649-56. Epub 2004 Jun 2.

PMID:
15175276
12.

Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5-A3 genetic locus and lung cancer risk.

Wang J, Spitz MR, Amos CI, Wilkinson AV, Wu X, Shete S.

Cancer. 2010 Jul 15;116(14):3458-62. doi: 10.1002/cncr.25085.

13.

Association of IREB2 and CHRNA3/5 polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population.

Zhou H, Yang J, Li D, Xiao J, Wang B, Wang L, Ma C, Xu S, Ou X, Feng Y.

J Hum Genet. 2012 Nov 26;57(11):738-46. doi: 10.1038/jhg.2012.104. Epub 2012 Aug 23.

PMID:
22914670
14.

Genetic basis for susceptibility to lung cancer: Recent progress and future directions.

Yokota J, Shiraishi K, Kohno T.

Adv Cancer Res. 2010;109:51-72. doi: 10.1016/B978-0-12-380890-5.00002-8. Review.

PMID:
21070914
15.

Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk.

Wang Y, Broderick P, Matakidou A, Eisen T, Houlston RS.

PLoS One. 2011 Apr 29;6(4):e19085. doi: 10.1371/journal.pone.0019085.

16.

Nicotinic acetylcholine receptor variants associated with susceptibility to chronic obstructive pulmonary disease: a meta-analysis.

Zhang J, Summah H, Zhu YG, Qu JM.

Respir Res. 2011 Dec 17;12:158. doi: 10.1186/1465-9921-12-158. Review.

17.

Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.

Wang Y, Broderick P, Matakidou A, Eisen T, Houlston RS.

Carcinogenesis. 2010 Feb;31(2):234-8. doi: 10.1093/carcin/bgp287. Epub 2009 Dec 2.

PMID:
19955392
18.

Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study.

Ryu E, Fridley BL, Tosakulwong N, Bailey KR, Edwards AO.

Mol Vis. 2010 Dec 17;16:2811-21.

19.

Role of a genetic variant on the 15q25.1 lung cancer susceptibility locus in smoking-associated nasopharyngeal carcinoma.

Ji X, Zhang W, Gui J, Fan X, Zhang W, Li Y, An G, Zhu D, Hu Q.

PLoS One. 2014 Oct 20;9(10):e109036. doi: 10.1371/journal.pone.0109036. eCollection 2014.

20.

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis.

Chen LS, Hung RJ, Baker T, Horton A, Culverhouse R, Saccone N, Cheng I, Deng B, Han Y, Hansen HM, Horsman J, Kim C, Lutz S, Rosenberger A, Aben KK, Andrew AS, Breslau N, Chang SC, Dieffenbach AK, Dienemann H, Frederiksen B, Han J, Hatsukami DK, Johnson EO, Pande M, Wrensch MR, McLaughlin J, Skaug V, van der Heijden HF, Wampfler J, Wenzlaff A, Woll P, Zienolddiny S, Bickeböller H, Brenner H, Duell EJ, Haugen A, Heinrich J, Hokanson JE, Hunter DJ, Kiemeney LA, Lazarus P, Le Marchand L, Liu G, Mayordomo J, Risch A, Schwartz AG, Teare D, Wu X, Wiencke JK, Yang P, Zhang ZF, Spitz MR, Kraft P, Amos CI, Bierut LJ.

J Natl Cancer Inst. 2015 Apr 14;107(5). pii: djv100. doi: 10.1093/jnci/djv100. Print 2015 May. Review.

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