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Metabolomics reveals the metabolic shifts following an intervention with rye bread in postmenopausal women--a randomized control trial.

Moazzami AA, Bondia-Pons I, Hanhineva K, Juntunen K, Antl N, Poutanen K, Mykkänen H.

Nutr J. 2012 Oct 22;11:88. doi: 10.1186/1475-2891-11-88.


Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients.

Moazzami AA, Zhang JX, Kamal-Eldin A, Aman P, Hallmans G, Johansson JE, Andersson SO.

J Nutr. 2011 Dec;141(12):2126-32. doi: 10.3945/jn.111.148239. Epub 2011 Oct 19.


High-fiber rye bread and insulin secretion and sensitivity in healthy postmenopausal women.

Juntunen KS, Laaksonen DE, Poutanen KS, Niskanen LK, Mykkänen HM.

Am J Clin Nutr. 2003 Feb;77(2):385-91.


Metabolomic analysis of plasma metabolites that may mediate effects of rye bread on satiety and weight maintenance in postmenopausal women.

Lankinen M, Schwab U, Seppänen-Laakso T, Mattila I, Juntunen K, Mykkänen H, Poutanen K, Gylling H, Oresic M.

J Nutr. 2011 Jan;141(1):31-6. doi: 10.3945/jn.110.131656. Epub 2010 Nov 17.


Metabolomics reveals differences in postprandial responses to breads and fasting metabolic characteristics associated with postprandial insulin demand in postmenopausal women.

Moazzami AA, Shrestha A, Morrison DA, Poutanen K, Mykkänen H.

J Nutr. 2014 Jun;144(6):807-14. doi: 10.3945/jn.113.188912. Epub 2014 Apr 9.


Effects of unfermented and fermented whole grain rye crisp breads served as part of a standardized breakfast, on appetite and postprandial glucose and insulin responses: a randomized cross-over trial.

Johansson DP, Lee I, Risérus U, Langton M, Landberg R.

PLoS One. 2015 Mar 31;10(3):e0122241. doi: 10.1371/journal.pone.0122241. eCollection 2015.


The postprandial plasma rye fingerprint includes benzoxazinoid-derived phenylacetamide sulfates.

Hanhineva K, Keski-Rahkonen P, Lappi J, Katina K, Pekkinen J, Savolainen O, Timonen O, Paananen J, Mykkänen H, Poutanen K.

J Nutr. 2014 Jul;144(7):1016-22. doi: 10.3945/jn.113.187237. Epub 2014 May 8.


Postprandial glucose metabolism and SCFA after consuming wholegrain rye bread and wheat bread enriched with bioprocessed rye bran in individuals with mild gastrointestinal symptoms.

Lappi J, Mykkänen H, Bach Knudsen KE, Kirjavainen P, Katina K, Pihlajamäki J, Poutanen K, Kolehmainen M.

Nutr J. 2014 Nov 4;13:104. doi: 10.1186/1475-2891-13-104.


Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread.

Bondia-Pons I, Nordlund E, Mattila I, Katina K, Aura AM, Kolehmainen M, Orešič M, Mykkänen H, Poutanen K.

Nutr J. 2011 Oct 19;10:116. doi: 10.1186/1475-2891-10-116.


Multicompartmental nontargeted LC-MS metabolomics: explorative study on the metabolic responses of rye fiber versus refined wheat fiber intake in plasma and urine of hypercholesterolemic pigs.

Nørskov NP, Hedemann MS, Lærke HN, Knudsen KE.

J Proteome Res. 2013 Jun 7;12(6):2818-32. doi: 10.1021/pr400164b. Epub 2013 May 8.


Structural differences between rye and wheat breads but not total fiber content may explain the lower postprandial insulin response to rye bread.

Juntunen KS, Laaksonen DE, Autio K, Niskanen LK, Holst JJ, Savolainen KE, Liukkonen KH, Poutanen KS, Mykkänen HM.

Am J Clin Nutr. 2003 Nov;78(5):957-64.


Effects of concentrated arabinoxylan and β-glucan compared with refined wheat and whole grain rye on glucose and appetite in subjects with the metabolic syndrome: a randomized study.

Hartvigsen ML, Gregersen S, Lærke HN, Holst JJ, Bach Knudsen KE, Hermansen K.

Eur J Clin Nutr. 2014 Jan;68(1):84-90. doi: 10.1038/ejcn.2013.236. Epub 2013 Nov 20.


Similar metabolic responses in pigs and humans to breads with different contents and compositions of dietary fibers: a metabolomics study.

Nielsen KL, Hartvigsen ML, Hedemann MS, Lærke HN, Hermansen K, Bach Knudsen KE.

Am J Clin Nutr. 2014 Apr;99(4):941-9. doi: 10.3945/ajcn.113.074724. Epub 2014 Jan 29.


Berries reduce postprandial insulin responses to wheat and rye breads in healthy women.

Törrönen R, Kolehmainen M, Sarkkinen E, Poutanen K, Mykkänen H, Niskanen L.

J Nutr. 2013 Apr;143(4):430-6. doi: 10.3945/jn.112.169771. Epub 2013 Jan 30.


Intake of whole-grain and fiber-rich rye bread versus refined wheat bread does not differentiate intestinal microbiota composition in Finnish adults with metabolic syndrome.

Lappi J, Salojärvi J, Kolehmainen M, Mykkänen H, Poutanen K, de Vos WM, Salonen A.

J Nutr. 2013 May;143(5):648-55. doi: 10.3945/jn.112.172668. Epub 2013 Mar 20.


Effects of whole-grain rye porridge with added inulin and wheat gluten on appetite, gut fermentation and postprandial glucose metabolism: a randomised, cross-over, breakfast study.

Lee I, Shi L, Webb DL, Hellström PM, Risérus U, Landberg R.

Br J Nutr. 2016 Dec;116(12):2139-2149. doi: 10.1017/S0007114516004153. Epub 2017 Jan 10.


NMR-based metabonomics reveals that plasma betaine increases upon intake of high-fiber rye buns in hypercholesterolemic pigs.

Bertram HC, Malmendal A, Nielsen NC, Straadt IK, Larsen T, Knudsen KE, Laerke HN.

Mol Nutr Food Res. 2009 Aug;53(8):1055-62. doi: 10.1002/mnfr.200800344.


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