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Items: 1 to 20 of 68

1.

Insufficient autophagy in idiopathic pulmonary fibrosis.

Araya J, Kojima J, Takasaka N, Ito S, Fujii S, Hara H, Yanagisawa H, Kobayashi K, Tsurushige C, Kawaishi M, Kamiya N, Hirano J, Odaka M, Morikawa T, Nishimura SL, Kawabata Y, Hano H, Nakayama K, Kuwano K.

Am J Physiol Lung Cell Mol Physiol. 2013 Jan 1;304(1):L56-69. doi: 10.1152/ajplung.00213.2012. Epub 2012 Oct 19.

PMID:
23087019
2.

Cellular senescence and autophagy in the pathogenesis of chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF).

Kuwano K, Araya J, Hara H, Minagawa S, Takasaka N, Ito S, Kobayashi K, Nakayama K.

Respir Investig. 2016 Nov;54(6):397-406. doi: 10.1016/j.resinv.2016.03.010. Epub 2016 May 24. Review.

PMID:
27886850
3.

Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells.

Minagawa S, Araya J, Numata T, Nojiri S, Hara H, Yumino Y, Kawaishi M, Odaka M, Morikawa T, Nishimura SL, Nakayama K, Kuwano K.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L391-401. doi: 10.1152/ajplung.00097.2010. Epub 2010 Dec 17.

4.

Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis.

Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, Sato N, Yoshida M, Tsubouchi K, Kurita Y, Ito S, Fujita Y, Takasaka N, Utsumi H, Yanagisawa H, Hashimoto M, Wakui H, Kojima J, Shimizu K, Numata T, Kawaishi M, Kaneko Y, Asano H, Yamashita M, Odaka M, Morikawa T, Nakayama K, Kuwano K.

J Immunol. 2016 Jul 15;197(2):504-16. doi: 10.4049/jimmunol.1600265. Epub 2016 Jun 8.

5.

Autophagy in idiopathic pulmonary fibrosis.

Patel AS, Lin L, Geyer A, Haspel JA, An CH, Cao J, Rosas IO, Morse D.

PLoS One. 2012;7(7):e41394. doi: 10.1371/journal.pone.0041394. Epub 2012 Jul 18.

6.

A possible involvement of p62/sequestosome-1 in the process of biliary epithelial autophagy and senescence in primary biliary cirrhosis.

Sasaki M, Miyakoshi M, Sato Y, Nakanuma Y.

Liver Int. 2012 Mar;32(3):487-99. doi: 10.1111/j.1478-3231.2011.02656.x. Epub 2011 Sep 27.

PMID:
22098537
7.

Regulation of 26S Proteasome Activity in Pulmonary Fibrosis.

Semren N, Welk V, Korfei M, Keller IE, Fernandez IE, Adler H, Günther A, Eickelberg O, Meiners S.

Am J Respir Crit Care Med. 2015 Nov 1;192(9):1089-101. doi: 10.1164/rccm.201412-2270OC.

PMID:
26207697
8.

Recent advances in molecular targets and treatment of idiopathic pulmonary fibrosis: focus on TGFbeta signaling and the myofibroblast.

Gharaee-Kermani M, Hu B, Phan SH, Gyetko MR.

Curr Med Chem. 2009;16(11):1400-17. Review.

PMID:
19355895
9.

Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema.

Chilosi M, Carloni A, Rossi A, Poletti V.

Transl Res. 2013 Sep;162(3):156-73. doi: 10.1016/j.trsl.2013.06.004. Epub 2013 Jul 2.

PMID:
23831269
10.

Relaxin regulates myofibroblast contractility and protects against lung fibrosis.

Huang X, Gai Y, Yang N, Lu B, Samuel CS, Thannickal VJ, Zhou Y.

Am J Pathol. 2011 Dec;179(6):2751-65. doi: 10.1016/j.ajpath.2011.08.018. Epub 2011 Oct 6.

11.

Autophagy impairment induces premature senescence in primary human fibroblasts.

Kang HT, Lee KB, Kim SY, Choi HR, Park SC.

PLoS One. 2011;6(8):e23367. doi: 10.1371/journal.pone.0023367. Epub 2011 Aug 8.

12.

Compartmentalized expression of c-FLIP in lung tissues of patients with idiopathic pulmonary fibrosis.

Cha SI, Groshong SD, Frankel SK, Edelman BL, Cosgrove GP, Terry-Powers JL, Remigio LK, Curran-Everett D, Brown KK, Cool CD, Riches DW.

Am J Respir Cell Mol Biol. 2010 Feb;42(2):140-8. doi: 10.1165/rcmb.2008-0419OC. Epub 2009 Apr 16.

13.

Autophagy in the pathogenesis of pulmonary disease.

Araya J, Hara H, Kuwano K.

Intern Med. 2013;52(20):2295-303. Review.

14.

Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence.

Horikawa I, Fujita K, Jenkins LM, Hiyoshi Y, Mondal AM, Vojtesek B, Lane DP, Appella E, Harris CC.

Nat Commun. 2014 Aug 21;5:4706. doi: 10.1038/ncomms5706.

PMID:
25144556
15.

p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells.

Viiri J, Hyttinen JM, Ryhänen T, Rilla K, Paimela T, Kuusisto E, Siitonen A, Urtti A, Salminen A, Kaarniranta K.

Mol Vis. 2010 Jul 27;16:1399-414.

16.

Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy.

Kurita Y, Araya J, Minagawa S, Hara H, Ichikawa A, Saito N, Kadota T, Tsubouchi K, Sato N, Yoshida M, Kobayashi K, Ito S, Fujita Y, Utsumi H, Yanagisawa H, Hashimoto M, Wakui H, Yoshii Y, Ishikawa T, Numata T, Kaneko Y, Asano H, Yamashita M, Odaka M, Morikawa T, Nakayama K, Kuwano K.

Respir Res. 2017 Jun 2;18(1):114. doi: 10.1186/s12931-017-0600-3.

17.

Insufficient autophagy promotes bronchial epithelial cell senescence in chronic obstructive pulmonary disease.

Fujii S, Hara H, Araya J, Takasaka N, Kojima J, Ito S, Minagawa S, Yumino Y, Ishikawa T, Numata T, Kawaishi M, Hirano J, Odaka M, Morikawa T, Nishimura S, Nakayama K, Kuwano K.

Oncoimmunology. 2012 Aug 1;1(5):630-641.

18.

NBR1 cooperates with p62 in selective autophagy of ubiquitinated targets.

Kirkin V, Lamark T, Johansen T, Dikic I.

Autophagy. 2009 Jul;5(5):732-3. Epub 2009 Jul 30.

PMID:
19398892
19.

Evolving concepts of apoptosis in idiopathic pulmonary fibrosis.

Thannickal VJ, Horowitz JC.

Proc Am Thorac Soc. 2006 Jun;3(4):350-6. Review.

20.

Role of protease-activated receptor-2 in idiopathic pulmonary fibrosis.

Wygrecka M, Kwapiszewska G, Jablonska E, von Gerlach S, Henneke I, Zakrzewicz D, Guenther A, Preissner KT, Markart P.

Am J Respir Crit Care Med. 2011 Jun 15;183(12):1703-14. doi: 10.1164/rccm.201009-1479OC. Epub 2011 Mar 11.

PMID:
21471103

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