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Localized deferoxamine injection augments vascularity and improves bony union in pathologic fracture healing after radiotherapy.

Donneys A, Weiss DM, Deshpande SS, Ahsan S, Tchanque-Fossuo CN, Sarhaddi D, Levi B, Goldstein SA, Buchman SR.

Bone. 2013 Jan;52(1):318-25. doi: 10.1016/j.bone.2012.10.014.


Deferoxamine restores callus size, mineralization, and mechanical strength in fracture healing after radiotherapy.

Donneys A, Ahsan S, Perosky JE, Deshpande SS, Tchanque-Fossuo CN, Levi B, Kozloff KM, Buchman SR.

Plast Reconstr Surg. 2013 May;131(5):711e-9e. doi: 10.1097/PRS.0b013e3182865c57.


Targeting angiogenesis as a therapeutic means to reinforce osteocyte survival and prevent nonunions in the aftermath of radiotherapy.

Donneys A, Nelson NS, Page EE, Deshpande SS, Felice PA, Tchanque-Fossuo CN, Spiegel JP, Buchman SR.

Head Neck. 2015 Sep;37(9):1261-7. doi: 10.1002/hed.23744.


Deferoxamine reverses radiation induced hypovascularity during bone regeneration and repair in the murine mandible.

Farberg AS, Jing XL, Monson LA, Donneys A, Tchanque-Fossuo CN, Deshpande SS, Buchman SR.

Bone. 2012 May;50(5):1184-7. doi: 10.1016/j.bone.2012.01.019.


Deferoxamine expedites consolidation during mandibular distraction osteogenesis.

Donneys A, Deshpande SS, Tchanque-Fossuo CN, Johnson KL, Blough JT, Perosky JE, Kozloff KM, Felice PA, Nelson NS, Farberg AS, Levi B, Buchman SR.

Bone. 2013 Aug;55(2):384-90. doi: 10.1016/j.bone.2013.04.005.


Amifostine protects vascularity and improves union in a model of irradiated mandibular fracture healing.

Sarhaddi D, Tchanque-Fossuo CN, Poushanchi B, Donneys A, Deshpande SS, Weiss DM, Buchman SR.

Plast Reconstr Surg. 2013 Dec;132(6):1542-9. doi: 10.1097/PRS.0b013e3182a80766.


Amifostine preserves osteocyte number and osteoid formation in fracture healing following radiotherapy.

Donneys A, Tchanque-Fossuo CN, Blough JT, Nelson NS, Deshpande SS, Buchman SR.

J Oral Maxillofac Surg. 2014 Mar;72(3):559-66. doi: 10.1016/j.joms.2013.09.006.


Deferoxamine enhances neovascularization and accelerates wound healing in diabetic rats via the accumulation of hypoxia-inducible factor-1α.

Hou Z, Nie C, Si Z, Ma Y.

Diabetes Res Clin Pract. 2013 Jul;101(1):62-71. doi: 10.1016/j.diabres.2013.04.012.


Bone regeneration in distraction osteogenesis demonstrates significantly increased vascularity in comparison to fracture repair in the mandible.

Donneys A, Tchanque-Fossuo CN, Farberg AS, Deshpande SS, Buchman SR.

J Craniofac Surg. 2012 Jan;23(1):328-32. doi: 10.1097/SCS.0b013e318241db26.


Prevention of radiation-induced bone pathology through combined pharmacologic cytoprotection and angiogenic stimulation.

Donneys A, Nelson NS, Perosky JE, Polyatskaya Y, Rodriguez JJ, Figueredo C, Vasseli CA, Ratliff HC, Deshpande SS, Kozloff KM, Buchman SR.

Bone. 2016 Mar;84:245-52. doi: 10.1016/j.bone.2015.12.051.


Role of parathyroid hormone therapy in reversing radiation-induced nonunion and normalization of radiomorphometrics in a murine mandibular model of distraction osteogenesis.

Gallagher KK, Deshpande S, Tchanque-Fossuo CN, Donneys A, Sarhaddi D, Nelson NS, Chepeha DB, Buchman SR.

Head Neck. 2013 Dec;35(12):1732-7. doi: 10.1002/hed.23216.


An evaluation of carrier agents for desferoxamine, an up-regulator of vascular endothelial growth factor.

Hertzberg BP, Holt JB, Graff RD, Gilbert SR, Dahners LE.

J Biomater Appl. 2013 May;27(8):1046-54. doi: 10.1177/0885328211433137.


Microdensitometric and microarchitectural alterations in irradiated mandibular fracture repair.

Inyang AF, Tchanque-Fossuo CN, Merati M, Radzolsky ER, Buchman SR.

J Craniofac Surg. 2014 Nov;25(6):2022-6. doi: 10.1097/SCS.0000000000000520.


Deferoxamine enhances the vascular response of bone regeneration in mandibular distraction osteogenesis.

Donneys A, Farberg AS, Tchanque-Fossuo CN, Deshpande SS, Buchman SR.

Plast Reconstr Surg. 2012 Apr;129(4):850-6. doi: 10.1097/PRS.0b013e31824422f2.


The effect of Amifostine prophylaxis on bone densitometry, biomechanical strength and union in mandibular pathologic fracture repair.

Tchanque-Fossuo CN, Donneys A, Sarhaddi D, Poushanchi B, Deshpande SS, Weiss DM, Buchman SR.

Bone. 2013 Nov;57(1):56-61. doi: 10.1016/j.bone.2013.07.005.


Increasing vascularity to improve healing of a segmental defect of the rat femur.

Stewart R, Goldstein J, Eberhardt A, Chu GT, Gilbert S.

J Orthop Trauma. 2011 Aug;25(8):472-6. doi: 10.1097/BOT.0b013e31822588d8.


Translational treatment paradigm for managing non-unions secondary to radiation injury utilizing adipose derived stem cells and angiogenic therapy.

Donneys A, Blough JT, Nelson NS, Perosky JE, Deshpande SS, Kang SY, Felice PA, Figueredo C, Peterson JR, Kozloff KM, Levi B, Chepeha DB, Buchman SR.

Head Neck. 2016 Apr;38 Suppl 1:E837-43. doi: 10.1002/hed.24110.


Gene expression of TGF-beta, TGF-beta receptor, and extracellular matrix proteins during membranous bone healing in rats.

Steinbrech DS, Mehrara BJ, Rowe NM, Dudziak ME, Luchs JS, Saadeh PB, Gittes GK, Longaker MT.

Plast Reconstr Surg. 2000 May;105(6):2028-38.


Deferoxamine released from poly(lactic-co-glycolic acid) promotes healing of osteoporotic bone defect via enhanced angiogenesis and osteogenesis.

Jia P, Chen H, Kang H, Qi J, Zhao P, Jiang M, Guo L, Zhou Q, Qian ND, Zhou HB, Xu YJ, Fan Y, Deng LF.

J Biomed Mater Res A. 2016 Oct;104(10):2515-27. doi: 10.1002/jbm.a.35793.


DFO enhances the targeting of CD34-positive cells and improves neovascularization.

Du Z, Zan T, Huang X, Sheng L, Li H, Li H, Li Q.

Cell Transplant. 2015;24(11):2353-66. doi: 10.3727/096368914X685753.

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