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A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails.

Wilusz JE, JnBaptiste CK, Lu LY, Kuhn CD, Joshua-Tor L, Sharp PA.

Genes Dev. 2012 Nov 1;26(21):2392-407. doi: 10.1101/gad.204438.112. Epub 2012 Oct 16.


Long noncoding RNAs: Re-writing dogmas of RNA processing and stability.

Wilusz JE.

Biochim Biophys Acta. 2016 Jan;1859(1):128-38. doi: 10.1016/j.bbagrm.2015.06.003. Epub 2015 Jun 11. Review.


Life without A tail: new formats of long noncoding RNAs.

Zhang Y, Yang L, Chen LL.

Int J Biochem Cell Biol. 2014 Sep;54:338-49. doi: 10.1016/j.biocel.2013.10.009. Epub 2013 Oct 26. Review.


Formation of triple-helical structures by the 3'-end sequences of MALAT1 and MENβ noncoding RNAs.

Brown JA, Valenstein ML, Yario TA, Tycowski KT, Steitz JA.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19202-7. doi: 10.1073/pnas.1217338109. Epub 2012 Nov 5.


Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix.

Brown JA, Bulkley D, Wang J, Valenstein ML, Yario TA, Steitz TA, Steitz JA.

Nat Struct Mol Biol. 2014 Jul;21(7):633-40. doi: 10.1038/nsmb.2844. Epub 2014 Jun 22.


microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus.

Leucci E, Patella F, Waage J, Holmstrøm K, Lindow M, Porse B, Kauppinen S, Lund AH.

Sci Rep. 2013;3:2535. doi: 10.1038/srep02535.


A 3' Poly(A) Tract Is Required for LINE-1 Retrotransposition.

Doucet AJ, Wilusz JE, Miyoshi T, Liu Y, Moran JV.

Mol Cell. 2015 Dec 3;60(5):728-41. doi: 10.1016/j.molcel.2015.10.012. Epub 2015 Nov 12.


Natural antisense RNA promotes 3' end processing and maturation of MALAT1 lncRNA.

Zong X, Nakagawa S, Freier SM, Fei J, Ha T, Prasanth SG, Prasanth KV.

Nucleic Acids Res. 2016 Apr 7;44(6):2898-908. doi: 10.1093/nar/gkw047. Epub 2016 Jan 29.


3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA.

Wilusz JE, Freier SM, Spector DL.

Cell. 2008 Nov 28;135(5):919-32. doi: 10.1016/j.cell.2008.10.012.


Long non-coding RNAs: a new frontier in the study of human diseases.

Shi X, Sun M, Liu H, Yao Y, Song Y.

Cancer Lett. 2013 Oct 10;339(2):159-66. doi: 10.1016/j.canlet.2013.06.013. Epub 2013 Jun 18. Review.


Polyadenylation-dependent control of long noncoding RNA expression by the poly(A)-binding protein nuclear 1.

Beaulieu YB, Kleinman CL, Landry-Voyer AM, Majewski J, Bachand F.

PLoS Genet. 2012;8(11):e1003078. doi: 10.1371/journal.pgen.1003078. Epub 2012 Nov 15.


Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth.

Michalik KM, You X, Manavski Y, Doddaballapur A, Zörnig M, Braun T, John D, Ponomareva Y, Chen W, Uchida S, Boon RA, Dimmeler S.

Circ Res. 2014 Apr 25;114(9):1389-97. doi: 10.1161/CIRCRESAHA.114.303265. Epub 2014 Mar 6.


Hoogsteen-position pyrimidines promote the stability and function of the MALAT1 RNA triple helix.

Brown JA, Kinzig CG, DeGregorio SJ, Steitz JA.

RNA. 2016 May;22(5):743-9. doi: 10.1261/rna.055707.115. Epub 2016 Mar 7.


Targeting long non-coding RNAs in cancers: progress and prospects.

Li CH, Chen Y.

Int J Biochem Cell Biol. 2013 Aug;45(8):1895-910. doi: 10.1016/j.biocel.2013.05.030. Epub 2013 Jun 4. Review.


MALAT1 -- a paradigm for long noncoding RNA function in cancer.

Gutschner T, Hämmerle M, Diederichs S.

J Mol Med (Berl). 2013 Jul;91(7):791-801. doi: 10.1007/s00109-013-1028-y. Epub 2013 Mar 26. Review.


Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs.

Dhir A, Dhir S, Proudfoot NJ, Jopling CL.

Nat Struct Mol Biol. 2015 Apr;22(4):319-27. doi: 10.1038/nsmb.2982. Epub 2015 Mar 2.


Long noncoding RNAs: Novel insights into hepatocelluar carcinoma.

He Y, Meng XM, Huang C, Wu BM, Zhang L, Lv XW, Li J.

Cancer Lett. 2014 Mar 1;344(1):20-7. doi: 10.1016/j.canlet.2013.10.021. Epub 2013 Oct 30. Review.


Silencing of long noncoding RNA MALAT1 by miR-101 and miR-217 inhibits proliferation, migration, and invasion of esophageal squamous cell carcinoma cells.

Wang X, Li M, Wang Z, Han S, Tang X, Ge Y, Zhou L, Zhou C, Yuan Q, Yang M.

J Biol Chem. 2015 Feb 13;290(7):3925-35. doi: 10.1074/jbc.M114.596866. Epub 2014 Dec 23.


Long noncoding RNAs are rarely translated in two human cell lines.

Bánfai B, Jia H, Khatun J, Wood E, Risk B, Gundling WE Jr, Kundaje A, Gunawardena HP, Yu Y, Xie L, Krajewski K, Strahl BD, Chen X, Bickel P, Giddings MC, Brown JB, Lipovich L.

Genome Res. 2012 Sep;22(9):1646-57. doi: 10.1101/gr.134767.111.

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