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Items: 1 to 20 of 108

1.

Syntheses and structure-activity relationship studies of N-substituted-β-D-glucosaminides as selective cytotoxic agents.

Wang B, Liu Y, Wang Y, Liu X, Cheng MS.

Bioorg Med Chem Lett. 2012 Dec 1;22(23):7110-3. doi: 10.1016/j.bmcl.2012.09.075. Epub 2012 Sep 28.

PMID:
23067549
2.

Synthesis and tumor cytotoxicity of novel amide derivatives of β-hederin.

Liu Y, Lu WX, Yan MC, Yu Y, Ikejima T, Cheng MS.

Molecules. 2010 Nov 3;15(11):7871-83. doi: 10.3390/molecules15117871.

3.

Synthesis, cytotoxic evaluation, docking and in silico pharmacokinetic prediction of 4-arylideneamino/cycloalkylidineamino 1, 2-naphthoquinone thiosemicarbazones.

Shukla S, Srivastava RS, Shrivastava SK, Sodhi A, Kumar P.

J Enzyme Inhib Med Chem. 2013 Dec;28(6):1192-8. doi: 10.3109/14756366.2012.721783. Epub 2012 Sep 14.

PMID:
22978426
4.

Triterpenoid saponins from Xanthoceras sorbifolia Bunge and their inhibitory activity on human cancer cell lines.

Yu L, Wang X, Wei X, Wang M, Chen L, Cao S, Kang N, Qiu F.

Bioorg Med Chem Lett. 2012 Aug 15;22(16):5232-8. doi: 10.1016/j.bmcl.2012.06.061. Epub 2012 Jun 28.

PMID:
22801644
5.

Structural analogues of diosgenyl saponins: synthesis and anticancer activity.

Kaskiw MJ, Tassotto ML, Mok M, Tokar SL, Pycko R, Th'ng J, Jiang ZH.

Bioorg Med Chem. 2009 Nov 15;17(22):7670-9. doi: 10.1016/j.bmc.2009.09.046. Epub 2009 Sep 26.

PMID:
19819703
6.

Synthesis and cytotoxic effect of pseudodiosgenyl saponins with thio-ring F.

Zan X, Gao J, Gu G, Liu S, Sun B, Liu L, Lou HX.

Bioorg Med Chem Lett. 2014 Mar 15;24(6):1600-4. doi: 10.1016/j.bmcl.2014.01.055. Epub 2014 Jan 28.

PMID:
24534485
7.

Synthesis and cytotoxicities of icogenin analogues with disaccharide residues.

Wang H, Su F, Zhou L, Chen X, Lei P.

Bioorg Med Chem Lett. 2009 May 15;19(10):2796-800. doi: 10.1016/j.bmcl.2009.03.092. Epub 2009 Mar 26.

PMID:
19362474
8.

Activity of Saponins from Medicago species Against HeLa and MCF-7 Cell Lines and their Capacity to Potentiate Cisplatin Effect.

Avato P, Migoni D, Argentieri M, Fanizzi FP, Tava A.

Anticancer Agents Med Chem. 2017 Nov 24;17(11):1508-1518. doi: 10.2174/1871520617666170727152805.

PMID:
28748756
9.

Synthesis of novel spirostanic saponins and their cytotoxic activity.

Hernández JC, León F, Brouard I, Torres F, Rubio S, Quintana J, Estévez F, Bermejo J.

Bioorg Med Chem. 2008 Feb 15;16(4):2063-76. Epub 2007 Nov 4.

PMID:
18023191
10.

Natural product-based design, synthesis and biological evaluation of Albiziabioside A derivatives that selectively induce HCT116 cell death.

Wei G, Cui S, Luan W, Wang S, Hou Z, Liu Y, Liu Y, Cheng M.

Eur J Med Chem. 2016 May 4;113:92-101. doi: 10.1016/j.ejmech.2015.12.034. Epub 2015 Dec 21.

PMID:
26922223
11.

13,28-Epoxy triterpenoid saponins from Ardisia japonica selectively inhibit proliferation of liver cancer cells without affecting normal liver cells.

Li Q, Li W, Hui LP, Zhao CY, He L, Koike K.

Bioorg Med Chem Lett. 2012 Oct 1;22(19):6120-5. doi: 10.1016/j.bmcl.2012.08.027. Epub 2012 Aug 14.

PMID:
22940450
12.

Concise synthesis and antitumor activities of trisaccharide steroidal saponins.

Gu G, Fang M, Liu J, Gu L.

Carbohydr Res. 2011 Nov 8;346(15):2406-13. doi: 10.1016/j.carres.2011.08.026. Epub 2011 Sep 1.

PMID:
21943550
13.

Synthesis and cytotoxic activity of diosgenyl saponin analogues.

Kaskiw MJ, Tassotto ML, Th'ng J, Jiang ZH.

Bioorg Med Chem. 2008 Mar 15;16(6):3209-17. doi: 10.1016/j.bmc.2007.12.022. Epub 2007 Dec 27.

PMID:
18164206
14.

Synthesis of the A,B-ring-truncated OSW saponin analogs and their antitumor activities.

Peng W, Tang P, Hu X, Liu JO, Yu B.

Bioorg Med Chem Lett. 2007 Oct 15;17(20):5506-9. Epub 2007 Aug 29.

PMID:
17826089
15.

Synthesis and antiproliferative effect of novel curcumin analogues.

Liu B, Xia M, Ji X, Xu L, Dong J.

Chem Pharm Bull (Tokyo). 2013;61(7):757-63. Epub 2013 May 11.

16.

New insights into the structure-cytotoxicity relationship of spirostan saponins and related glycosides.

Pérez-Labrada K, Brouard I, Estévez S, Marrero MT, Estévez F, Bermejo J, Rivera DG.

Bioorg Med Chem. 2012 Apr 15;20(8):2690-700. doi: 10.1016/j.bmc.2012.02.026. Epub 2012 Feb 15.

PMID:
22405922
17.

Antitumor activity of Pulsatilla koreana saponins and their structure-activity relationship.

Bang SC, Lee JH, Song GY, Kim DH, Yoon MY, Ahn BZ.

Chem Pharm Bull (Tokyo). 2005 Nov;53(11):1451-4.

18.

Synthesis of stryphnoside A, a triterpene saponin isolated from the pericarps of Stryphnodendron fissuratum.

Lv X, Yu S, Wang J, Du Y.

Carbohydr Res. 2011 Sep 27;346(13):1786-91. doi: 10.1016/j.carres.2011.06.006. Epub 2011 Jun 12.

PMID:
21798521
19.

Synthesis of cholestane glycosides bearing OSW-1 disaccharide or its 1-->4-linked analogue and their antitumor activities.

Zheng D, Zhou L, Guan Y, Chen X, Zhou W, Chen X, Lei P.

Bioorg Med Chem Lett. 2010 Sep 15;20(18):5439-42. doi: 10.1016/j.bmcl.2010.07.085. Epub 2010 Jul 29.

PMID:
20719510
20.

Synthesis, characterization and biological studies of diosgenyl analogues.

Huang B, Du D, Zhang R, Wu X, Xing Z, He Y, Huang W.

Bioorg Med Chem Lett. 2012 Dec 15;22(24):7330-4. doi: 10.1016/j.bmcl.2012.10.086. Epub 2012 Oct 23.

PMID:
23153797

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