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Items: 1 to 20 of 89

1.

The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier).

Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Jackson G, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian ZS, Sutherland M, Abushakra S, Lewcock J, Farese R, Kenet RO, Laferla F, Perrin S, Whitaker S, Honig L, Mesulam MM, Boeve B, Grossman M, Miller BL, Cummings JL.

Alzheimers Dement. 2013 Mar;9(2):189-98. doi: 10.1016/j.jalz.2012.03.003. Epub 2012 Oct 10. Review.

2.

Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development.

Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian Z, Sutherland M, Farese R, Miller BL, Cummings J.

Alzheimers Dement. 2013 Mar;9(2):176-88. doi: 10.1016/j.jalz.2012.03.002. Epub 2012 Oct 5. Review.

3.

Frontotemporal lobar degeneration: epidemiology, pathology, diagnosis and management.

Seltman RE, Matthews BR.

CNS Drugs. 2012 Oct 1;26(10):841-70. doi: 10.2165/11640070-000000000-00000. Review.

PMID:
22950490
4.

An open-label study of memantine treatment in 3 subtypes of frontotemporal lobar degeneration.

Boxer AL, Lipton AM, Womack K, Merrilees J, Neuhaus J, Pavlic D, Gandhi A, Red D, Martin-Cook K, Svetlik D, Miller BL.

Alzheimer Dis Assoc Disord. 2009 Jul-Sep;23(3):211-7. doi: 10.1097/WAD.0b013e318197852f.

5.

Microarray gene and miRNA expression studies: looking for new therapeutic targets for frontotemporal lobar degeneration.

Milanesi E, Pilotto A.

Drug Dev Res. 2014 Sep;75(6):366-71. doi: 10.1002/ddr.21224. Review.

PMID:
25195580
6.

From frontotemporal lobar degeneration pathology to frontotemporal lobar degeneration biomarkers.

Hales CM, Hu WT.

Int Rev Psychiatry. 2013 Apr;25(2):210-20. doi: 10.3109/09540261.2013.776522. Review.

PMID:
23611350
7.

Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration.

Rohrer JD, Lashley T, Schott JM, Warren JE, Mead S, Isaacs AM, Beck J, Hardy J, de Silva R, Warrington E, Troakes C, Al-Sarraj S, King A, Borroni B, Clarkson MJ, Ourselin S, Holton JL, Fox NC, Revesz T, Rossor MN, Warren JD.

Brain. 2011 Sep;134(Pt 9):2565-81. doi: 10.1093/brain/awr198.

8.

Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy.

Behrouzi R, Liu X, Wu D, Robinson AC, Tanaguchi-Watanabe S, Rollinson S, Shi J, Tian J, Hamdalla HH, Ealing J, Richardson A, Jones M, Pickering-Brown S, Davidson YS, Strong MJ, Hasegawa M, Snowden JS, Mann DM.

Acta Neuropathol Commun. 2016 Mar 31;4:33. doi: 10.1186/s40478-016-0301-z.

9.

The clinical diagnosis of early-onset dementias: diagnostic accuracy and clinicopathological relationships.

Snowden JS, Thompson JC, Stopford CL, Richardson AM, Gerhard A, Neary D, Mann DM.

Brain. 2011 Sep;134(Pt 9):2478-92. doi: 10.1093/brain/awr189. Epub 2011 Aug 11.

PMID:
21840888
10.

Saccade abnormalities in autopsy-confirmed frontotemporal lobar degeneration and Alzheimer disease.

Boxer AL, Garbutt S, Seeley WW, Jafari A, Heuer HW, Mirsky J, Hellmuth J, Trojanowski JQ, Huang E, DeArmond S, Neuhaus J, Miller BL.

Arch Neurol. 2012 Apr;69(4):509-17. doi: 10.1001/archneurol.2011.1021.

11.

Memantine in patients with frontotemporal lobar degeneration: a multicentre, randomised, double-blind, placebo-controlled trial.

Boxer AL, Knopman DS, Kaufer DI, Grossman M, Onyike C, Graf-Radford N, Mendez M, Kerwin D, Lerner A, Wu CK, Koestler M, Shapira J, Sullivan K, Klepac K, Lipowski K, Ullah J, Fields S, Kramer JH, Merrilees J, Neuhaus J, Mesulam MM, Miller BL.

Lancet Neurol. 2013 Feb;12(2):149-56. doi: 10.1016/S1474-4422(12)70320-4. Epub 2013 Jan 2.

12.

Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration.

Scherling CS, Hall T, Berisha F, Klepac K, Karydas A, Coppola G, Kramer JH, Rabinovici G, Ahlijanian M, Miller BL, Seeley W, Grinberg LT, Rosen H, Meredith J Jr, Boxer AL.

Ann Neurol. 2014 Jan;75(1):116-26. doi: 10.1002/ana.24052. Epub 2014 Jan 2.

13.

[Frontotemporal dementia: a review].

Chauvire V, Even C, Thuile J, Rouillon F, Guelfi JD.

Encephale. 2007 Dec;33(6):933-40. doi: 10.1016/j.encep.2006.12.001. Epub 2007 Sep 6. Review. French.

PMID:
18789785
14.

Frontotemporal lobar degeneration: new understanding brings new approaches.

Tartaglia MC.

Neuroimaging Clin N Am. 2012 Feb;22(1):83-97, viii. doi: 10.1016/j.nic.2011.11.009. Review.

PMID:
22284735
15.

Cerebrospinal fluid proteomics and protein biomarkers in frontotemporal lobar degeneration: Current status and future perspectives.

Oeckl P, Steinacker P, Feneberg E, Otto M.

Biochim Biophys Acta. 2015 Jul;1854(7):757-68. doi: 10.1016/j.bbapap.2014.12.010. Epub 2014 Dec 17. Review.

PMID:
25526887
16.

Frontotemporal dementia: recommendations for therapeutic studies, designs, and approaches.

Freedman M.

Can J Neurol Sci. 2007 Mar;34 Suppl 1:S118-24. Review.

PMID:
17469694
17.

Frontotemporal dementia: An updated overview.

Mohandas E, Rajmohan V.

Indian J Psychiatry. 2009 Jan;51 Suppl 1:S65-9.

18.

[History and classification of frontotemporal lobar degeneration].

Okamoto K.

Brain Nerve. 2009 Nov;61(11):1203-8. Japanese.

PMID:
19938676
19.

Mutations in progranulin (GRN) within the spectrum of clinical and pathological phenotypes of frontotemporal dementia.

van Swieten JC, Heutink P.

Lancet Neurol. 2008 Oct;7(10):965-74. doi: 10.1016/S1474-4422(08)70194-7. Epub 2008 Sep 2. Review.

PMID:
18771956
20.

Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration.

Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL 3rd, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Mann DM; Consortium for Frontotemporal Lobar Degeneration..

Acta Neuropathol. 2007 Jul;114(1):5-22. Epub 2007 Jun 20.

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