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Items: 1 to 20 of 223

1.

Rhinovirus attenuates non-typeable Hemophilus influenzae-stimulated IL-8 responses via TLR2-dependent degradation of IRAK-1.

Unger BL, Faris AN, Ganesan S, Comstock AT, Hershenson MB, Sajjan US.

PLoS Pathog. 2012;8(10):e1002969. doi: 10.1371/journal.ppat.1002969. Epub 2012 Oct 4.

2.

TLR2 Activation Limits Rhinovirus-Stimulated CXCL-10 by Attenuating IRAK-1-Dependent IL-33 Receptor Signaling in Human Bronchial Epithelial Cells.

Ganesan S, Pham D, Jing Y, Farazuddin M, Hudy MH, Unger B, Comstock AT, Proud D, Lauring AS, Sajjan US.

J Immunol. 2016 Sep 15;197(6):2409-20. doi: 10.4049/jimmunol.1502702. Epub 2016 Aug 8.

3.

Induction of beta defensin 2 by NTHi requires TLR2 mediated MyD88 and IRAK-TRAF6-p38MAPK signaling pathway in human middle ear epithelial cells.

Lee HY, Takeshita T, Shimada J, Akopyan A, Woo JI, Pan H, Moon SK, Andalibi A, Park RK, Kang SH, Kang SS, Gellibolian R, Lim DJ.

BMC Infect Dis. 2008 Jun 25;8:87. doi: 10.1186/1471-2334-8-87.

4.

Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B.

Xu F, Xu Z, Zhang R, Wu Z, Lim JH, Koga T, Li JD, Shen H.

Respir Res. 2008 Jan 31;9:16. doi: 10.1186/1465-9921-9-16.

5.

The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung.

Wieland CW, Florquin S, Maris NA, Hoebe K, Beutler B, Takeda K, Akira S, van der Poll T.

J Immunol. 2005 Nov 1;175(9):6042-9.

6.

Rhinovirus disrupts the barrier function of polarized airway epithelial cells.

Sajjan U, Wang Q, Zhao Y, Gruenert DC, Hershenson MB.

Am J Respir Crit Care Med. 2008 Dec 15;178(12):1271-81. doi: 10.1164/rccm.200801-136OC. Epub 2008 Sep 11.

7.

H. influenzae potentiates airway epithelial cell responses to rhinovirus by increasing ICAM-1 and TLR3 expression.

Sajjan US, Jia Y, Newcomb DC, Bentley JK, Lukacs NW, LiPuma JJ, Hershenson MB.

FASEB J. 2006 Oct;20(12):2121-3. Epub 2006 Aug 16.

PMID:
16914605
8.

Toll-like receptor 9 is not important for host defense against Haemophilus influenzae.

Wieland CW, Florquin S, van der Poll T.

Immunobiology. 2010 Nov;215(11):910-4. doi: 10.1016/j.imbio.2009.10.004. Epub 2009 Nov 25.

PMID:
19942314
9.

Human rhinovirus 1B exposure induces phosphatidylinositol 3-kinase-dependent airway inflammation in mice.

Newcomb DC, Sajjan US, Nagarkar DR, Wang Q, Nanua S, Zhou Y, McHenry CL, Hennrick KT, Tsai WC, Bentley JK, Lukacs NW, Johnston SL, Hershenson MB.

Am J Respir Crit Care Med. 2008 May 15;177(10):1111-21. doi: 10.1164/rccm.200708-1243OC. Epub 2008 Feb 14.

10.

Haemophilus influenzae increases the susceptibility and inflammatory response of airway epithelial cells to viral infections.

Gulraiz F, Bellinghausen C, Bruggeman CA, Stassen FR.

FASEB J. 2015 Mar;29(3):849-58. doi: 10.1096/fj.14-254359. Epub 2014 Nov 19.

PMID:
25411435
11.

Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages.

Nagarkar DR, Bowman ER, Schneider D, Wang Q, Shim J, Zhao Y, Linn MJ, McHenry CL, Gosangi B, Bentley JK, Tsai WC, Sajjan US, Lukacs NW, Hershenson MB.

J Immunol. 2010 Aug 15;185(4):2525-35. doi: 10.4049/jimmunol.1000286. Epub 2010 Jul 19.

12.

TLR4-mediated induction of TLR2 signaling is critical in the pathogenesis and resolution of otitis media.

Leichtle A, Hernandez M, Pak K, Yamasaki K, Cheng CF, Webster NJ, Ryan AF, Wasserman SI.

Innate Immun. 2009 Aug;15(4):205-15. doi: 10.1177/1753425909103170. Epub 2009 Jul 8.

13.
14.

Lipooligosaccharides containing phosphorylcholine delay pulmonary clearance of nontypeable Haemophilus influenzae.

Pang B, Winn D, Johnson R, Hong W, West-Barnette S, Kock N, Swords WE.

Infect Immun. 2008 May;76(5):2037-43. doi: 10.1128/IAI.01716-07. Epub 2008 Mar 17.

15.

Human neutrophil elastase degrades SPLUNC1 and impairs airway epithelial defense against bacteria.

Jiang D, Wenzel SE, Wu Q, Bowler RP, Schnell C, Chu HW.

PLoS One. 2013 May 31;8(5):e64689. doi: 10.1371/journal.pone.0064689. Print 2013.

16.

Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable Haemophilus influenzae-exacerbated neutrophilia in mice.

Nikota JK, Shen P, Morissette MC, Fernandes K, Roos A, Chu DK, Barra NG, Iwakura Y, Kolbeck R, Humbles AA, Stampfli MR.

J Immunol. 2014 Sep 15;193(6):3134-45. doi: 10.4049/jimmunol.1302412. Epub 2014 Aug 4.

18.

Toll-like receptor 4 mediates innate immune responses to Haemophilus influenzae infection in mouse lung.

Wang X, Moser C, Louboutin JP, Lysenko ES, Weiner DJ, Weiser JN, Wilson JM.

J Immunol. 2002 Jan 15;168(2):810-5.

19.

Impaired innate immune alveolar macrophage response and the predilection for COPD exacerbations.

Berenson CS, Kruzel RL, Eberhardt E, Dolnick R, Minderman H, Wallace PK, Sethi S.

Thorax. 2014 Sep;69(9):811-8. doi: 10.1136/thoraxjnl-2013-203669. Epub 2014 Mar 31.

PMID:
24686454
20.

Rhinovirus infection liberates planktonic bacteria from biofilm and increases chemokine responses in cystic fibrosis airway epithelial cells.

Chattoraj SS, Ganesan S, Jones AM, Helm JM, Comstock AT, Bright-Thomas R, LiPuma JJ, Hershenson MB, Sajjan US.

Thorax. 2011 Apr;66(4):333-9. doi: 10.1136/thx.2010.151431. Epub 2011 Feb 2.

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