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Identification of anaphase promoting complex substrates in S. cerevisiae.

Ostapenko D, Burton JL, Solomon MJ.

PLoS One. 2012;7(9):e45895. doi: 10.1371/journal.pone.0045895. Epub 2012 Sep 26.


Anaphase promoting complex-dependent degradation of transcriptional repressors Nrm1 and Yhp1 in Saccharomyces cerevisiae.

Ostapenko D, Solomon MJ.

Mol Biol Cell. 2011 Jul 1;22(13):2175-84. doi: 10.1091/mbc.E11-01-0031. Epub 2011 May 11.


Unique D box and KEN box sequences limit ubiquitination of Acm1 and promote pseudosubstrate inhibition of the anaphase-promoting complex.

Choi E, Dial JM, Jeong DE, Hall MC.

J Biol Chem. 2008 Aug 29;283(35):23701-10. doi: 10.1074/jbc.M803695200. Epub 2008 Jul 2.


APC/CCdh1 specific degradation of Hsl1 and Clb2 is required for proper stress responses of S. cerevisiae.

Simpson-Lavy KJ, Sajman J, Zenvirth D, Brandeis M.

Cell Cycle. 2009 Sep 15;8(18):3003-9. Epub 2009 Sep 25.


Substrate Recognition by the Cdh1 Destruction Box Receptor Is a General Requirement for APC/CCdh1-mediated Proteolysis.

Qin L, Guimarães DS, Melesse M, Hall MC.

J Biol Chem. 2016 Jul 22;291(30):15564-74. doi: 10.1074/jbc.M116.731190. Epub 2016 May 23. Erratum in: J Biol Chem. 2017 Mar 24;292(12 ):5125-5127.


Mechanisms of pseudosubstrate inhibition of the anaphase promoting complex by Acm1.

Burton JL, Xiong Y, Solomon MJ.

EMBO J. 2011 May 4;30(9):1818-29. doi: 10.1038/emboj.2011.90. Epub 2011 Apr 1.


Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor.

da Fonseca PC, Kong EH, Zhang Z, Schreiber A, Williams MA, Morris EP, Barford D.

Nature. 2011 Feb 10;470(7333):274-8. doi: 10.1038/nature09625. Epub 2010 Nov 24.


Hsl1p, a Swe1p inhibitor, is degraded via the anaphase-promoting complex.

Burton JL, Solomon MJ.

Mol Cell Biol. 2000 Jul;20(13):4614-25.


The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C).

Sczaniecka M, Feoktistova A, May KM, Chen JS, Blyth J, Gould KL, Hardwick KG.

J Biol Chem. 2008 Aug 22;283(34):23039-47. doi: 10.1074/jbc.M803594200. Epub 2008 Jun 13.


Pseudosubstrate inhibition of the anaphase-promoting complex by Acm1: regulation by proteolysis and Cdc28 phosphorylation.

Ostapenko D, Burton JL, Wang R, Solomon MJ.

Mol Cell Biol. 2008 Aug;28(15):4653-64. doi: 10.1128/MCB.00055-08. Epub 2008 Jun 2.


Assembly of an APC-Cdh1-substrate complex is stimulated by engagement of a destruction box.

Burton JL, Tsakraklides V, Solomon MJ.

Mol Cell. 2005 May 27;18(5):533-42.


Insights into the cellular mechanism of the yeast ubiquitin ligase APC/C-Cdh1 from the analysis of in vivo degrons.

Arnold L, Höckner S, Seufert W.

Mol Biol Cell. 2015 Mar 1;26(5):843-58. doi: 10.1091/mbc.E14-09-1342. Epub 2014 Dec 24.


Phosphorylation and dephosphorylation regulate APC/C(Cdh1) substrate degradation.

Simpson-Lavy KJ, Zenvirth D, Brandeis M.

Cell Cycle. 2015;14(19):3138-45. doi: 10.1080/15384101.2015.1078036.


Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis.

Sorensen CS, Lukas C, Kramer ER, Peters JM, Bartek J, Lukas J.

Mol Cell Biol. 2000 Oct;20(20):7613-23.


Inhibition of APC-mediated proteolysis by the meiosis-specific protein kinase Ime2.

Bolte M, Steigemann P, Braus GH, Irniger S.

Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4385-90. Epub 2002 Mar 26.


The APC/C: a smörgåsbord for proteolysis.

Pines J.

Mol Cell. 2009 Apr 24;34(2):135-6. doi: 10.1016/j.molcel.2009.04.006.

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