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Items: 1 to 20 of 106

1.

Lack of expression of MTAP in uncommon T-cell lymphomas.

Bertino JR, Lubin M, Johnson-Farley N, Chan WC, Goodell L, Bhagavathi S.

Clin Lymphoma Myeloma Leuk. 2012 Oct;12(5):306-9. doi: 10.1016/j.clml.2012.07.001.

PMID:
23040436
3.

Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies.

Bertino JR, Waud WR, Parker WB, Lubin M.

Cancer Biol Ther. 2011 Apr 1;11(7):627-32. Epub 2011 Apr 1. Review.

4.

Synthesis of purines in human lymphoblast cells deficient in methylthioadenosine phosphorylase activity.

Gordon RB, Blackwell K, Emmerson BT.

Biochim Biophys Acta. 1987 Jan 19;927(1):1-7.

PMID:
3098299
5.

Methylthioadenosine phosphorylase cDNA transfection alters sensitivity to depletion of purine and methionine in A549 lung cancer cells.

Hori H, Tran P, Carrera CJ, Hori Y, Rosenbach MD, Carson DA, Nobori T.

Cancer Res. 1996 Dec 15;56(24):5653-8.

6.

Methylthioadenosine phosphorylase (MTAP)-deficient T-cell ALL xenografts are sensitive to pralatrexate and 6-thioguanine alone and in combination.

Tedeschi PM, Kathari YK, Johnson-Farley N, Bertino JR.

Cancer Chemother Pharmacol. 2015 Jun;75(6):1247-52. doi: 10.1007/s00280-015-2747-2. Epub 2015 Apr 28.

7.

Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers.

Coulthard SA, Redfern CP, Vikingsson S, Lindqvist-Appell M, Skoglund K, Jakobsen-Falk I, Hall AG, Taylor GA, Hogarth LA.

Mol Cancer Ther. 2011 Mar;10(3):495-504. doi: 10.1158/1535-7163.MCT-10-0798. Epub 2011 Jan 31.

8.

Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy.

Lubin M, Lubin A.

PLoS One. 2009 May 29;4(5):e5735. doi: 10.1371/journal.pone.0005735. Erratum in: PLoS One. 2010;5(4). doi: 10.1371/annotation/54fad81d-c975-4b30-bb2b-249650ec3d66.

9.

Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro.

Batova A, Diccianni MB, Omura-Minamisawa M, Yu J, Carrera CJ, Bridgeman LJ, Kung FH, Pullen J, Amylon MD, Yu AL.

Cancer Res. 1999 Apr 1;59(7):1492-7.

10.

Chemotherapy targeting methylthioadenosine phosphorylase (MTAP) deficiency in adult T cell leukemia (ATL).

Harasawa H, Yamada Y, Kudoh M, Sugahara K, Soda H, Hirakata Y, Sasaki H, Ikeda S, Matsuo T, Tomonaga M, Nobori T, Kamihira S.

Leukemia. 2002 Sep;16(9):1799-807.

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14.

Methylthioadenosine phosphorylase as target for chemoselective treatment of T-cell acute lymphoblastic leukemic cells.

Efferth T, Miyachi H, Drexler HG, Gebhart E.

Blood Cells Mol Dis. 2002 Jan-Feb;28(1):47-56.

PMID:
11987241
15.

Lack of methylthioadenosine phosphorylase expression in mantle cell lymphoma is associated with shorter survival: implications for a potential targeted therapy.

Marcé S, Balagué O, Colomo L, Martinez A, Höller S, Villamor N, Bosch F, Ott G, Rosenwald A, Leoni L, Esteller M, Fraga MF, Montserrat E, Colomer D, Campo E.

Clin Cancer Res. 2006 Jun 15;12(12):3754-61.

17.

Mice heterozygous for germ-line mutations in methylthioadenosine phosphorylase (MTAP) die prematurely of T-cell lymphoma.

Kadariya Y, Yin B, Tang B, Shinton SA, Quinlivan EP, Hua X, Klein-Szanto A, Al-Saleem TI, Bassing CH, Hardy RR, Kruger WD.

Cancer Res. 2009 Jul 15;69(14):5961-9. doi: 10.1158/0008-5472.CAN-09-0145. Epub 2009 Jun 30.

18.

Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells.

Tang B, Testa JR, Kruger WD.

Cancer Biol Ther. 2012 Sep;13(11):1082-90. doi: 10.4161/cbt.21115. Epub 2012 Jul 24.

19.

Molecular characterization of 5'-deoxy-5'-methylthioadenosine phosphorylase-deficient mutant clones of murine lymphoma cell line R1.1.

Kadariya Y, Nishioka J, Nakamura A, Kato-Nakazawa K, Nobori T.

Cancer Sci. 2003 Jun;94(6):519-22.

20.

Genomic cloning of methylthioadenosine phosphorylase: a purine metabolic enzyme deficient in multiple different cancers.

Nobori T, Takabayashi K, Tran P, Orvis L, Batova A, Yu AL, Carson DA.

Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):6203-8.

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