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Items: 1 to 20 of 116

1.

Dipeptidyl peptidase-4 modulates left ventricular dysfunction in chronic heart failure via angiogenesis-dependent and -independent actions.

Shigeta T, Aoyama M, Bando YK, Monji A, Mitsui T, Takatsu M, Cheng XW, Okumura T, Hirashiki A, Nagata K, Murohara T.

Circulation. 2012 Oct 9;126(15):1838-51. doi: 10.1161/CIRCULATIONAHA.112.096479. Epub 2012 Oct 3.

2.

Beta-blocker improves survival, left ventricular function, and myocardial remodeling in hypertensive rats with diastolic heart failure.

Kobayashi M, Machida N, Mitsuishi M, Yamane Y.

Am J Hypertens. 2004 Dec;17(12 Pt 1):1112-9.

PMID:
15607617
3.

Circulating dipeptidyl peptidase IV activity correlates with cardiac dysfunction in human and experimental heart failure.

dos Santos L, Salles TA, Arruda-Junior DF, Campos LC, Pereira AC, Barreto AL, Antonio EL, Mansur AJ, Tucci PJ, Krieger JE, Girardi AC.

Circ Heart Fail. 2013 Sep 1;6(5):1029-38. doi: 10.1161/CIRCHEARTFAILURE.112.000057. Epub 2013 Jul 26.

4.

Inhibition of dipeptidyl peptidase-IV enzyme activity protects against myocardial ischemia-reperfusion injury in rats.

Chua S, Lee FY, Tsai TH, Sheu JJ, Leu S, Sun CK, Chen YL, Chang HW, Chai HT, Liu CF, Lu HI, Yip HK.

J Transl Med. 2014 Dec 13;12:357. doi: 10.1186/s12967-014-0357-0.

5.

GLP-1 signaling preserves cardiac function in endotoxemic Fischer 344 and DPP4-deficient rats.

Ku HC, Chen WP, Su MJ.

Naunyn Schmiedebergs Arch Pharmacol. 2010 Dec;382(5-6):463-74. doi: 10.1007/s00210-010-0559-9. Epub 2010 Sep 18.

PMID:
20852989
6.

Dipeptidyl peptidase IV inhibition improves cardiorenal function in overpacing-induced heart failure.

Gomez N, Touihri K, Matheeussen V, Mendes Da Costa A, Mahmoudabady M, Mathieu M, Baerts L, Peace A, Lybaert P, Scharpé S, De Meester I, Bartunek J, Vanderheyden M, Mc Entee K.

Eur J Heart Fail. 2012 Jan;14(1):14-21. doi: 10.1093/eurjhf/hfr146. Epub 2011 Nov 1.

7.

Inhibition of Dipeptidyl Peptidase-4 Impairs Ventricular Function and Promotes Cardiac Fibrosis in High Fat-Fed Diabetic Mice.

Mulvihill EE, Varin EM, Ussher JR, Campbell JE, Bang KW, Abdullah T, Baggio LL, Drucker DJ.

Diabetes. 2016 Mar;65(3):742-54. doi: 10.2337/db15-1224. Epub 2015 Dec 15.

8.

Dipeptidyl peptidase-4 inhibitors are associated with improved left ventricular diastolic function after acute myocardial infarction in diabetic patients.

Fujiwara T, Yoshida M, Nakamura T, Sakakura K, Wada H, Arao K, Katayama T, Funayama H, Sugawara Y, Mitsuhashi T, Kakei M, Momomura S, Ako J.

Heart Vessels. 2015 Sep;30(5):696-701. doi: 10.1007/s00380-014-0509-4. Epub 2014 Apr 16.

PMID:
24736945
9.

The activity of circulating dipeptidyl peptidase-4 is associated with subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus.

Ravassa S, Barba J, Coma-Canella I, Huerta A, López B, González A, Díez J.

Cardiovasc Diabetol. 2013 Oct 7;12:143. doi: 10.1186/1475-2840-12-143.

10.

Differential activation of matrix metalloproteinases in heart failure with and without ventricular dilatation.

Nishikawa N, Yamamoto K, Sakata Y, Mano T, Yoshida J, Miwa T, Takeda H, Hori M, Masuyama T.

Cardiovasc Res. 2003 Mar;57(3):766-74.

PMID:
12618238
11.

Altered dipeptidyl peptidase-4 activity during the progression of hyperinsulinemic obesity and islet atrophy in spontaneously late-stage type 2 diabetic rats.

Kirino Y, Sato Y, Kamimoto T, Kawazoe K, Minakuchi K.

Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E372-9. doi: 10.1152/ajpendo.00319.2010. Epub 2010 Dec 7.

12.

Dipeptidyl peptidase IV (DPP4)-deficiency attenuates diet-induced obesity in rats: possible implications for the hypothalamic neuropeptidergic system.

Stephan M, Radicke A, Leutloff S, Schmiedl A, Pabst R, von Hörsten S, Dettmer S, Lotz J, Nave H.

Behav Brain Res. 2011 Jan 20;216(2):712-8. doi: 10.1016/j.bbr.2010.09.024. Epub 2010 Sep 29.

PMID:
20887754
13.

Heart Failure as a Comorbidity of Diabetes: Role of Dipeptidyl Peptidase 4.

Bando YK, Murohara T.

J Atheroscler Thromb. 2016;23(2):147-54. doi: 10.5551/jat.33225. Epub 2015 Nov 26. Review.

14.

DA-1229, a novel and potent DPP4 inhibitor, improves insulin resistance and delays the onset of diabetes.

Kim MK, Chae YN, Kim HD, Yang EK, Cho EJ, Choi SH, Cheong YH, Kim HS, Kim HJ, Jo YW, Son MH, Kim SH, Shin CY.

Life Sci. 2012 Jan 2;90(1-2):21-9. doi: 10.1016/j.lfs.2011.10.007. Epub 2011 Oct 20.

PMID:
22056373
15.

Lack of tissue inhibitor of metalloproteinases 2 leads to exacerbated left ventricular dysfunction and adverse extracellular matrix remodeling in response to biomechanical stress.

Kandalam V, Basu R, Moore L, Fan D, Wang X, Jaworski DM, Oudit GY, Kassiri Z.

Circulation. 2011 Nov 8;124(19):2094-105. doi: 10.1161/CIRCULATIONAHA.111.030338. Epub 2011 Oct 10.

16.

Diastolic heart failure: evidence of increased myocardial collagen turnover linked to diastolic dysfunction.

Martos R, Baugh J, Ledwidge M, O'Loughlin C, Conlon C, Patle A, Donnelly SC, McDonald K.

Circulation. 2007 Feb 20;115(7):888-95. Epub 2007 Feb 5.

17.

Paradoxical impairment of angiogenesis, endothelial function and circulating number of endothelial progenitor cells in DPP4-deficient rat after critical limb ischemia.

Sun CK, Leu S, Sheu JJ, Tsai TH, Sung HC, Chen YL, Chung SY, Ko SF, Chang HW, Yip HK.

Stem Cell Res Ther. 2013 Mar 21;4(2):31. doi: 10.1186/scrt181.

18.

Grape seed-derived procyanidins decrease dipeptidyl-peptidase 4 activity and expression.

González-Abuín N, Martínez-Micaelo N, Blay M, Pujadas G, Garcia-Vallvé S, Pinent M, Ardévol A.

J Agric Food Chem. 2012 Sep 12;60(36):9055-61. doi: 10.1021/jf3010349. Epub 2012 Aug 30.

PMID:
22891874
19.

Bisoprolol inhibits sodium current in ventricular myocytes of rats with diastolic heart failure.

Tang HF, Wu SL, Deng CY, Zhang WC, Kuang SJ.

Clin Exp Pharmacol Physiol. 2007 Aug;34(8):714-9.

PMID:
17600546
20.

Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients.

Krijnen PA, Hahn NE, Kholová I, Baylan U, Sipkens JA, van Alphen FP, Vonk AB, Simsek S, Meischl C, Schalkwijk CG, van Buul JD, van Hinsbergh VW, Niessen HW.

Basic Res Cardiol. 2012 Jan;107(1):233. doi: 10.1007/s00395-011-0233-5. Epub 2011 Dec 14.

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