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Items: 1 to 20 of 133

1.

Involvement of histone demethylase LSD1 in short-time-scale gene expression changes during cell cycle progression in embryonic stem cells.

Nair VD, Ge Y, Balasubramaniyan N, Kim J, Okawa Y, Chikina M, Troyanskaya O, Sealfon SC.

Mol Cell Biol. 2012 Dec;32(23):4861-76. doi: 10.1128/MCB.00816-12. Epub 2012 Oct 1.

2.

Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability.

Foster CT, Dovey OM, Lezina L, Luo JL, Gant TW, Barlev N, Bradley A, Cowley SM.

Mol Cell Biol. 2010 Oct;30(20):4851-63. doi: 10.1128/MCB.00521-10. Epub 2010 Aug 16.

3.

Histone lysine-specific demethylase 1 (LSD1) protein is involved in Sal-like protein 4 (SALL4)-mediated transcriptional repression in hematopoietic stem cells.

Liu L, Souto J, Liao W, Jiang Y, Li Y, Nishinakamura R, Huang S, Rosengart T, Yang VW, Schuster M, Ma Y, Yang J.

J Biol Chem. 2013 Nov 29;288(48):34719-28. doi: 10.1074/jbc.M113.506568. Epub 2013 Oct 25.

4.

p53-targeted LSD1 functions in repression of chromatin structure and transcription in vivo.

Tsai WW, Nguyen TT, Shi Y, Barton MC.

Mol Cell Biol. 2008 Sep;28(17):5139-46. doi: 10.1128/MCB.00287-08. Epub 2008 Jun 23.

5.

Enhancer decommissioning by LSD1 during embryonic stem cell differentiation.

Whyte WA, Bilodeau S, Orlando DA, Hoke HA, Frampton GM, Foster CT, Cowley SM, Young RA.

Nature. 2012 Feb 1;482(7384):221-5. doi: 10.1038/nature10805.

6.

Cell cycle association of the retinoblastoma protein Rb and the histone demethylase LSD1 with the Epstein-Barr virus latency promoter Cp.

Chau CM, Deng Z, Kang H, Lieberman PM.

J Virol. 2008 Apr;82(7):3428-37. doi: 10.1128/JVI.01412-07. Epub 2008 Jan 23.

7.

Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A.

Macfarlan TS, Gifford WD, Agarwal S, Driscoll S, Lettieri K, Wang J, Andrews SE, Franco L, Rosenfeld MG, Ren B, Pfaff SL.

Genes Dev. 2011 Mar 15;25(6):594-607. doi: 10.1101/gad.2008511. Epub 2011 Feb 28.

8.

Transrepressive function of TLX requires the histone demethylase LSD1.

Yokoyama A, Takezawa S, Schüle R, Kitagawa H, Kato S.

Mol Cell Biol. 2008 Jun;28(12):3995-4003. doi: 10.1128/MCB.02030-07. Epub 2008 Apr 7.

9.

Lysine-specific demethylase 1 (LSD1) Is required for the transcriptional repression of the telomerase reverse transcriptase (hTERT) gene.

Zhu Q, Liu C, Ge Z, Fang X, Zhang X, Strååt K, Björkholm M, Xu D.

PLoS One. 2008 Jan 16;3(1):e1446. doi: 10.1371/journal.pone.0001446.

10.

Regulation of LSD1 histone demethylase activity by its associated factors.

Shi YJ, Matson C, Lan F, Iwase S, Baba T, Shi Y.

Mol Cell. 2005 Sep 16;19(6):857-64.

11.

Crystal structure of human histone lysine-specific demethylase 1 (LSD1).

Chen Y, Yang Y, Wang F, Wan K, Yamane K, Zhang Y, Lei M.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):13956-61. Epub 2006 Sep 6.

12.

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription.

Metzger E, Wissmann M, Yin N, Müller JM, Schneider R, Peters AH, Günther T, Buettner R, Schüle R.

Nature. 2005 Sep 15;437(7057):436-9. Epub 2005 Aug 3.

PMID:
16079795
13.

Histone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiation.

Guo Y, Fu X, Jin Y, Sun J, Liu Y, Huo B, Li X, Hu X.

Drug Des Devel Ther. 2015 Jun 19;9:3153-62. doi: 10.2147/DDDT.S81911. eCollection 2015.

14.

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis.

Hu X, Li X, Valverde K, Fu X, Noguchi C, Qiu Y, Huang S.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10141-6. doi: 10.1073/pnas.0900437106. Epub 2009 Jun 3.

15.

A novel mammalian flavin-dependent histone demethylase.

Karytinos A, Forneris F, Profumo A, Ciossani G, Battaglioli E, Binda C, Mattevi A.

J Biol Chem. 2009 Jun 26;284(26):17775-82. doi: 10.1074/jbc.M109.003087. Epub 2009 Apr 30.

16.

LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells.

Adamo A, Sesé B, Boue S, Castaño J, Paramonov I, Barrero MJ, Izpisua Belmonte JC.

Nat Cell Biol. 2011 Jun;13(6):652-9. doi: 10.1038/ncb2246. Epub 2011 May 22.

PMID:
21602794
17.

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.

Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Shi Y.

Cell. 2004 Dec 29;119(7):941-53.

18.

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.

Wissmann M, Yin N, Müller JM, Greschik H, Fodor BD, Jenuwein T, Vogler C, Schneider R, Günther T, Buettner R, Metzger E, Schüle R.

Nat Cell Biol. 2007 Mar;9(3):347-53. Epub 2007 Feb 4.

PMID:
17277772
19.

LSD1 regulates pluripotency of embryonic stem/carcinoma cells through histone deacetylase 1-mediated deacetylation of histone H4 at lysine 16.

Yin F, Lan R, Zhang X, Zhu L, Chen F, Xu Z, Liu Y, Ye T, Sun H, Lu F, Zhang H.

Mol Cell Biol. 2014 Jan;34(2):158-79. doi: 10.1128/MCB.00631-13. Epub 2013 Nov 4.

20.

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation.

Wang J, Hevi S, Kurash JK, Lei H, Gay F, Bajko J, Su H, Sun W, Chang H, Xu G, Gaudet F, Li E, Chen T.

Nat Genet. 2009 Jan;41(1):125-9. doi: 10.1038/ng.268. Epub 2008 Dec 21.

PMID:
19098913

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