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Items: 1 to 20 of 96

1.

Mesodermal Pten inactivation leads to alveolar capillary dysplasia- like phenotype.

Tiozzo C, Carraro G, Al Alam D, Baptista S, Danopoulos S, Li A, Lavarreda-Pearce M, Li C, De Langhe S, Chan B, Borok Z, Bellusci S, Minoo P.

J Clin Invest. 2012 Nov;122(11):3862-72.

2.

FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells.

Ren X, Ustiyan V, Pradhan A, Cai Y, Havrilak JA, Bolte CS, Shannon JM, Kalin TV, Kalinichenko VV.

Circ Res. 2014 Sep 26;115(8):709-20. doi: 10.1161/CIRCRESAHA.115.304382.

3.

PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer.

Guigon CJ, Zhao L, Willingham MC, Cheng SY.

Oncogene. 2009 Jan 29;28(4):509-17. doi: 10.1038/onc.2008.407.

4.

Inhibition of FOXO1/3 promotes vascular calcification.

Deng L, Huang L, Sun Y, Heath JM, Wu H, Chen Y.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):175-83. doi: 10.1161/ATVBAHA.114.304786.

5.

A novel FOXF1 mutation associated with alveolar capillary dysplasia and coexisting colobomas and hemihyperplasia.

Geddes GC, Dimmock DP, Hehir DA, Helbling DC, Kirkpatrick E, Loomba R, Southern J, Waknitz M, Scharer G, Konduri GG.

J Perinatol. 2015 Feb;35(2):155-7. doi: 10.1038/jp.2014.187.

PMID:
25627281
6.

A novel mutation in FOXF1 gene associated with alveolar capillary dysplasia with misalignment of pulmonary veins, intestinal malrotation and annular pancreas.

Miranda J, Rocha G, Soares P, Morgado H, Baptista MJ, Azevedo I, Fernandes S, Brandão O, Sen P, Guimarães H.

Neonatology. 2013;103(4):241-5. doi: 10.1159/000346062.

PMID:
23407133
7.

Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia.

Joza S, Wang J, Fox E, Hillman V, Ackerley C, Post M.

Am J Pathol. 2012 Dec;181(6):2003-17. doi: 10.1016/j.ajpath.2012.08.037.

PMID:
23063659
8.

Comparative analyses of lung transcriptomes in patients with alveolar capillary dysplasia with misalignment of pulmonary veins and in foxf1 heterozygous knockout mice.

Sen P, Dharmadhikari AV, Majewski T, Mohammad MA, Kalin TV, Zabielska J, Ren X, Bray M, Brown HM, Welty S, Thevananther S, Langston C, Szafranski P, Justice MJ, Kalinichenko VV, Gambin A, Belmont J, Stankiewicz P.

PLoS One. 2014 Apr 10;9(4):e94390. doi: 10.1371/journal.pone.0094390.

9.

PDK1 regulates vascular remodeling and promotes epithelial-mesenchymal transition in cardiac development.

Feng Q, Di R, Tao F, Chang Z, Lu S, Fan W, Shan C, Li X, Yang Z.

Mol Cell Biol. 2010 Jul;30(14):3711-21. doi: 10.1128/MCB.00420-10.

10.

Alveolar capillary dysplasia with misalignment of pulmonary [corrected] veins: concordance between pathological and molecular diagnosis.

Castilla-Fernandez Y, Copons-Fernández C, Jordan-Lucas R, Linde-Sillo Á, Valenzuela-Palafoll I, Ferreres Piñas JC, Moreno-Galdó A, Castillo-Salinas F.

J Perinatol. 2013 May;33(5):401-3. doi: 10.1038/jp.2012.63. Erratum in: J Perinatol. 2014 Feb;34(2):166.

PMID:
23624968
11.

Involvement of the PTEN-AKT-FOXO3a pathway in neuronal apoptosis in developing rat brain after hypoxia-ischemia.

Li D, Qu Y, Mao M, Zhang X, Li J, Ferriero D, Mu D.

J Cereb Blood Flow Metab. 2009 Dec;29(12):1903-13. doi: 10.1038/jcbfm.2009.102.

12.

Wild-type levels of the mouse Forkhead Box f1 gene are essential for lung repair.

Kalinichenko VV, Zhou Y, Shin B, Stolz DB, Watkins SC, Whitsett JA, Costa RH.

Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1253-65.

13.

A late presenter and long-term survivor of alveolar capillary dysplasia with misalignment of the pulmonary veins.

Ito Y, Akimoto T, Cho K, Yamada M, Tanino M, Dobata T, Kitaichi M, Kumaki S, Kinugawa Y.

Eur J Pediatr. 2015 Aug;174(8):1123-6. doi: 10.1007/s00431-015-2543-3.

PMID:
25899071
14.

PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells.

Ma J, Sawai H, Ochi N, Matsuo Y, Xu D, Yasuda A, Takahashi H, Wakasugi T, Takeyama H.

Mol Cell Biochem. 2009 Nov;331(1-2):161-71. doi: 10.1007/s11010-009-0154-x.

PMID:
19437103
15.

Effect of the IGF-1/PTEN/Akt/FoxO signaling pathway in the duodenal mucosa of rats subjected to water immersion and restraint stress.

Huang P, Zhou ZR, Zheng MQ, Shi FX.

Genet Mol Res. 2012 Sep 19;11(4):4775-88. doi: 10.4238/2012.September.19.2.

16.
17.

Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins.

Szafranski P, Gambin T, Dharmadhikari AV, Akdemir KC, Jhangiani SN, Schuette J, Godiwala N, Yatsenko SA, Sebastian J, Madan-Khetarpal S, Surti U, Abellar RG, Bateman DA, Wilson AL, Markham MH, Slamon J, Santos-Simarro F, Palomares M, Nevado J, Lapunzina P, Chung BH, Wong WL, Chu YW, Mok GT, Kerem E, Reiter J, Ambalavanan N, Anderson SA, Kelly DR, Shieh J, Rosenthal TC, Scheible K, Steiner L, Iqbal MA, McKinnon ML, Hamilton SJ, Schlade-Bartusiak K, English D, Hendson G, Roeder ER, DeNapoli TS, Littlejohn RO, Wolff DJ, Wagner CL, Yeung A, Francis D, Fiorino EK, Edelman M, Fox J, Hayes DA, Janssens S, De Baere E, Menten B, Loccufier A, Vanwalleghem L, Moerman P, Sznajer Y, Lay AS, Kussmann JL, Chawla J, Payton DJ, Phillips GE, Brosens E, Tibboel D, de Klein A, Maystadt I, Fisher R, Sebire N, Male A, Chopra M, Pinner J, Malcolm G, Peters G, Arbuckle S, Lees M, Mead Z, Quarrell O, Sayers R, Owens M, Shaw-Smith C, Lioy J, McKay E, de Leeuw N, Feenstra I, Spruijt L, Elmslie F, Thiruchelvam T, Bacino CA, Langston C, Lupski JR, Sen P, Popek E, Stankiewicz P.

Hum Genet. 2016 May;135(5):569-86. doi: 10.1007/s00439-016-1655-9.

PMID:
27071622
18.

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor α (ERRα).

Li Y, He L, Zeng N, Sahu D, Cadenas E, Shearn C, Li W, Stiles BL.

J Biol Chem. 2013 Aug 30;288(35):25007-24. doi: 10.1074/jbc.M113.450353.

19.

Insulin attenuates the insulin-like growth factor-I (IGF-I)-Akt pathway, not IGF-I-extracellularly regulated kinase pathway, in luteinized granulosa cells with an increase in PTEN.

Iwase A, Goto M, Harata T, Takigawa S, Nakahara T, Suzuki K, Manabe S, Kikkawa F.

J Clin Endocrinol Metab. 2009 Jun;94(6):2184-91. doi: 10.1210/jc.2008-1948.

PMID:
19318457
20.

miR-205 targets PTEN and PHLPP2 to augment AKT signaling and drive malignant phenotypes in non-small cell lung cancer.

Cai J, Fang L, Huang Y, Li R, Yuan J, Yang Y, Zhu X, Chen B, Wu J, Li M.

Cancer Res. 2013 Sep 1;73(17):5402-15. doi: 10.1158/0008-5472.CAN-13-0297.

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