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Items: 1 to 20 of 102


Sepsis chronically in MARS: systemic cytokine responses are always mixed regardless of the outcome, magnitude, or phase of sepsis.

Osuchowski MF, Craciun F, Weixelbaumer KM, Duffy ER, Remick DG.

J Immunol. 2012 Nov 1;189(9):4648-56. doi: 10.4049/jimmunol.1201806. Epub 2012 Sep 24.


Relationship between age/gender-induced survival changes and the magnitude of inflammatory activation and organ dysfunction in post-traumatic sepsis.

Drechsler S, Weixelbaumer K, Raeven P, Jafarmadar M, Khadem A, van Griensven M, Bahrami S, Osuchowski MF.

PLoS One. 2012;7(12):e51457. doi: 10.1371/journal.pone.0051457. Epub 2012 Dec 12.


Chronic sepsis mortality characterized by an individualized inflammatory response.

Osuchowski MF, Welch K, Yang H, Siddiqui J, Remick DG.

J Immunol. 2007 Jul 1;179(1):623-30.


Mechanisms of mortality in early and late sepsis.

Xiao H, Siddiqui J, Remick DG.

Infect Immun. 2006 Sep;74(9):5227-35.


Dynamics of hepatic gene expression profile in a rat cecal ligation and puncture model.

Yang Q, Mattick JS, Orman MA, Nguyen TT, Ierapetritou MG, Berthiaume F, Androulakis IP.

J Surg Res. 2012 Aug;176(2):583-600. doi: 10.1016/j.jss.2011.11.1031. Epub 2011 Dec 15.


Cecal ligation puncture procedure.

Toscano MG, Ganea D, Gamero AM.

J Vis Exp. 2011 May 7;(51). pii: 2860. doi: 10.3791/2860.


Untreated type 1 diabetes increases sepsis-induced mortality without inducing a prelethal cytokine response.

Osuchowski MF, Craciun FL, Schuller E, Sima C, Gyurko R, Remick DG.

Shock. 2010 Oct;34(4):369-76. doi: 10.1097/SHK.0b013e3181dc40a8.


Systemic inhibition and liver-specific over-expression of PAI-1 failed to improve survival in all-inclusive populations or homogenous cohorts of CLP mice.

Raeven P, Drechsler S, Weixelbaumer KM, Bastelica D, Peiretti F, Klotz A, Jafarmadar M, Redl H, Bahrami S, Alessi MC, Declerck PJ, Osuchowski MF.

J Thromb Haemost. 2014 Jun;12(6):958-69. doi: 10.1111/jth.12565.


Anti-inflammatory response is associated with mortality and severity of infection in sepsis.

Ashare A, Powers LS, Butler NS, Doerschug KC, Monick MM, Hunninghake GW.

Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L633-40. Epub 2004 Dec 3.


Mixed antagonist response and sepsis severity-dependent dysbalance of pro- and anti-inflammatory responses at the onset of postoperative sepsis.

Novotny AR, Reim D, Assfalg V, Altmayr F, Friess HM, Emmanuel K, Holzmann B.

Immunobiology. 2012 Jun;217(6):616-21. doi: 10.1016/j.imbio.2011.10.019. Epub 2011 Nov 3.


The protective effect of atractylenolide I on systemic inflammation in the mouse model of sepsis created by cecal ligation and puncture.

Wang A, Xiao Z, Zhou L, Zhang J, Li X, He Q.

Pharm Biol. 2016;54(1):146-50. doi: 10.3109/13880209.2015.1024330. Epub 2015 Apr 8.


Bayesian network analysis of multi-compartmentalized immune responses in a murine model of sepsis and direct lung injury.

Nemzek JA, Hodges AP, He Y.

BMC Res Notes. 2015 Sep 30;8:516. doi: 10.1186/s13104-015-1488-y.


Cecal ligation and puncture versus colon ascendens stent peritonitis: two distinct animal models for polymicrobial sepsis.

Maier S, Traeger T, Entleutner M, Westerholt A, Kleist B, Hüser N, Holzmann B, Stier A, Pfeffer K, Heidecke CD.

Shock. 2004 Jun;21(6):505-11.


Cecal ligation and puncture-induced murine sepsis does not cause lung injury.

Iskander KN, Craciun FL, Stepien DM, Duffy ER, Kim J, Moitra R, Vaickus LJ, Osuchowski MF, Remick DG.

Crit Care Med. 2013 Jan;41(1):159-70. doi: 10.1097/CCM.0b013e3182676322.


Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis.

Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF.

Intensive Care Med Exp. 2015 Dec;3(1):48. doi: 10.1186/s40635-015-0048-z. Epub 2015 Apr 7.


Location, location, location: cytokine concentrations are dependent on blood sampling site.

Mella JR, Chiswick EL, King E, Remick DG.

Shock. 2014 Oct;42(4):337-42. doi: 10.1097/SHK.0000000000000222.

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