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Items: 1 to 20 of 213

1.

The endogenous retroviral envelope protein syncytin-1 inhibits LPS/PHA-stimulated cytokine responses in human blood and is sorted into placental exosomes.

Tolosa JM, Schjenken JE, Clifton VL, Vargas A, Barbeau B, Lowry P, Maiti K, Smith R.

Placenta. 2012 Nov;33(11):933-41. doi: 10.1016/j.placenta.2012.08.004. Epub 2012 Sep 20.

PMID:
22999499
2.
3.

GCMa regulates the syncytin-mediated trophoblastic fusion.

Yu C, Shen K, Lin M, Chen P, Lin C, Chang GD, Chen H.

J Biol Chem. 2002 Dec 20;277(51):50062-8. Epub 2002 Oct 22.

4.

Endogenous retroviral syncytin: compilation of experimental research on syncytin and its possible role in normal and disturbed human placentogenesis.

Knerr I, Huppertz B, Weigel C, Dötsch J, Wich C, Schild RL, Beckmann MW, Rascher W.

Mol Hum Reprod. 2004 Aug;10(8):581-8. Epub 2004 Jun 4. Review.

PMID:
15181178
5.
6.

Immune cell activation by trophoblast-derived microvesicles is mediated by syncytin 1.

Holder BS, Tower CL, Forbes K, Mulla MJ, Aplin JD, Abrahams VM.

Immunology. 2012 Jun;136(2):184-91. doi: 10.1111/j.1365-2567.2012.03568.x.

7.

Expression of the fusogenic HERV-FRD Env glycoprotein (syncytin 2) in human placenta is restricted to villous cytotrophoblastic cells.

Malassiné A, Blaise S, Handschuh K, Lalucque H, Dupressoir A, Evain-Brion D, Heidmann T.

Placenta. 2007 Feb-Mar;28(2-3):185-91. Epub 2006 May 22.

PMID:
16714059
8.

Placental syncytins: Genetic disjunction between the fusogenic and immunosuppressive activity of retroviral envelope proteins.

Mangeney M, Renard M, Schlecht-Louf G, Bouallaga I, Heidmann O, Letzelter C, Richaud A, Ducos B, Heidmann T.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20534-9. Epub 2007 Dec 12.

9.

Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia.

Vargas A, Zhou S, Éthier-Chiasson M, Flipo D, Lafond J, Gilbert C, Barbeau B.

FASEB J. 2014 Aug;28(8):3703-19. doi: 10.1096/fj.13-239053. Epub 2014 May 8.

PMID:
24812088
10.

Functional characterization of the placental fusogenic membrane protein syncytin.

Chang C, Chen PT, Chang GD, Huang CJ, Chen H.

Biol Reprod. 2004 Dec;71(6):1956-62. Epub 2004 Jul 21.

PMID:
15269105
11.

Regulation of the human endogenous retroviral Syncytin-1 and cell-cell fusion by the nuclear hormone receptors PPARγ/RXRα in placentogenesis.

Ruebner M, Langbein M, Strissel PL, Henke C, Schmidt D, Goecke TW, Faschingbauer F, Schild RL, Beckmann MW, Strick R.

J Cell Biochem. 2012 Jul;113(7):2383-96. doi: 10.1002/jcb.24110.

PMID:
22573555
12.

Corticotropin-releasing hormone stimulates expression of leptin, 11beta-HSD2 and syncytin-1 in primary human trophoblasts.

Fahlbusch FB, Ruebner M, Volkert G, Offergeld R, Hartner A, Menendez-Castro C, Strick R, Rauh M, Rascher W, Dötsch J.

Reprod Biol Endocrinol. 2012 Sep 12;10:80. doi: 10.1186/1477-7827-10-80.

13.

Syncytin-2 plays an important role in the fusion of human trophoblast cells.

Vargas A, Moreau J, Landry S, LeBellego F, Toufaily C, Rassart E, Lafond J, Barbeau B.

J Mol Biol. 2009 Sep 18;392(2):301-18. doi: 10.1016/j.jmb.2009.07.025. Epub 2009 Jul 16.

PMID:
19616006
14.

Human placenta expresses and secretes NKG2D ligands via exosomes that down-modulate the cognate receptor expression: evidence for immunosuppressive function.

Hedlund M, Stenqvist AC, Nagaeva O, Kjellberg L, Wulff M, Baranov V, Mincheva-Nilsson L.

J Immunol. 2009 Jul 1;183(1):340-51. doi: 10.4049/jimmunol.0803477.

15.

C-Terminal truncations of syncytin-1 (ERVWE1 envelope) that increase its fusogenicity.

Drewlo S, Leyting S, Kokozidou M, Mallet F, Pötgens AJ.

Biol Chem. 2006 Aug;387(8):1113-20.

PMID:
16895482
16.

Structural characterization of the fusion core in syncytin, envelope protein of human endogenous retrovirus family W.

Gong R, Peng X, Kang S, Feng H, Huang J, Zhang W, Lin D, Tien P, Xiao G.

Biochem Biophys Res Commun. 2005 Jun 17;331(4):1193-200.

PMID:
15883002
17.

Reduced expression of both syncytin 1 and syncytin 2 correlates with severity of preeclampsia.

Vargas A, Toufaily C, LeBellego F, Rassart É, Lafond J, Barbeau B.

Reprod Sci. 2011 Nov;18(11):1085-91. doi: 10.1177/1933719111404608. Epub 2011 Apr 14.

PMID:
21493955
18.

A placenta-specific receptor for the fusogenic, endogenous retrovirus-derived, human syncytin-2.

Esnault C, Priet S, Ribet D, Vernochet C, Bruls T, Lavialle C, Weissenbach J, Heidmann T.

Proc Natl Acad Sci U S A. 2008 Nov 11;105(45):17532-7. doi: 10.1073/pnas.0807413105. Epub 2008 Nov 6.

19.

An endogenous retroviral envelope syncytin and its cognate receptor identified in the viviparous placental Mabuya lizard.

Cornelis G, Funk M, Vernochet C, Leal F, Tarazona OA, Meurice G, Heidmann O, Dupressoir A, Miralles A, Ramirez-Pinilla MP, Heidmann T.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):E10991-E11000. doi: 10.1073/pnas.1714590114. Epub 2017 Nov 21.

20.

Functional characterization of syncytin-A, a newly murine endogenous virus envelope protein. Implication for its fusion mechanism.

Peng X, Pan J, Gong R, Liu Y, Kang S, Feng H, Qiu G, Guo D, Tien P, Xiao G.

J Biol Chem. 2007 Jan 5;282(1):381-9. Epub 2006 Nov 14.

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