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Items: 1 to 20 of 110

1.

A kinetic clutch governs religation by type IB topoisomerases and determines camptothecin sensitivity.

Seol Y, Zhang H, Pommier Y, Neuman KC.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16125-30. doi: 10.1073/pnas.1206480109. Epub 2012 Sep 18.

2.

Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation.

Stivers JT, Harris TK, Mildvan AS.

Biochemistry. 1997 Apr 29;36(17):5212-22.

PMID:
9136883
3.

Structural insights into the function of type IB topoisomerases.

Redinbo MR, Champoux JJ, Hol WG.

Curr Opin Struct Biol. 1999 Feb;9(1):29-36.

PMID:
10047584
4.

Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors.

Seol Y, Zhang H, Agama K, Lorence N, Pommier Y, Neuman KC.

Mol Cancer Ther. 2015 Nov;14(11):2552-9. doi: 10.1158/1535-7163.MCT-15-0454. Epub 2015 Sep 8.

5.

Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB.

Koster DA, Croquette V, Dekker C, Shuman S, Dekker NH.

Nature. 2005 Mar 31;434(7033):671-4.

PMID:
15800630
6.

Free energy calculations reveal rotating-ratchet mechanism for DNA supercoil relaxation by topoisomerase IB and its inhibition.

Wereszczynski J, Andricioaei I.

Biophys J. 2010 Aug 4;99(3):869-78. doi: 10.1016/j.bpj.2010.04.077.

7.

A multiscale dynamic model of DNA supercoil relaxation by topoisomerase IB.

Lillian TD, Taranova M, Wereszczynski J, Andricioaei I, Perkins NC.

Biophys J. 2011 Apr 20;100(8):2016-23. doi: 10.1016/j.bpj.2011.03.003.

8.
9.
10.

Variola type IB DNA topoisomerase: DNA binding and supercoil unwinding using engineered DNA minicircles.

Anderson BG, Stivers JT.

Biochemistry. 2014 Jul 8;53(26):4302-15. doi: 10.1021/bi500571q. Epub 2014 Jun 26.

11.

Molecular mechanism of the camptothecin resistance of Glu710Gly topoisomerase IB mutant analyzed in vitro and in silico.

Tesauro C, Morozzo della Rocca B, Ottaviani A, Coletta A, Zuccaro L, Arnò B, D'Annessa I, Fiorani P, Desideri A.

Mol Cancer. 2013 Sep 3;12(1):100. doi: 10.1186/1476-4598-12-100.

12.

Single-molecule observations of topotecan-mediated TopIB activity at a unique DNA sequence.

Koster DA, Czerwinski F, Halby L, Crut A, Vekhoff P, Palle K, Arimondo PB, Dekker NH.

Nucleic Acids Res. 2008 Apr;36(7):2301-10. doi: 10.1093/nar/gkn035. Epub 2008 Feb 21.

13.

Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.

Colley WC, van der Merwe M, Vance JR, Burgin AB Jr, Bjornsti MA.

J Biol Chem. 2004 Dec 24;279(52):54069-78. Epub 2004 Oct 15.

14.

[DNA supercoiling and topoisomerases in Escherichia coli].

Gómez-Eichelmann MC, Camacho-Carranza R.

Rev Latinoam Microbiol. 1995 Jul-Sep;37(3):291-304. Review. Spanish.

PMID:
8850348
15.
16.

A small organic compound enhances the religation reaction of human topoisomerase I and identifies crucial elements for the religation mechanism.

Arnò B, Coletta A, Tesauro C, Zuccaro L, Fiorani P, Lentini S, Galloni P, Conte V, Floris B, Desideri A.

Biosci Rep. 2013 Mar 7;33(2):e00025. doi: 10.1042/BSR20120118.

17.

Investigating the role of the latch in the positive supercoiling mechanism of reverse gyrase.

Rodríguez AC.

Biochemistry. 2003 May 27;42(20):5993-6004.

PMID:
12755601
19.

Role of flexibility and long range communication on the function of human topoisomerase I.

Chillemi G, Fiorani P, Bruselles A, Castelli S, Campagna A, Sarra O, Tesauro C, Fiorentini M, Vassallo O, D'Annessa I, Santoleri S, Desideri A.

Ital J Biochem. 2007 Jun;56(2):110-4. Review.

PMID:
17722651
20.

Topoisomerase V relaxes supercoiled DNA by a constrained swiveling mechanism.

Taneja B, Schnurr B, Slesarev A, Marko JF, Mondragón A.

Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14670-5. Epub 2007 Sep 5.

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