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Genomic landscape of non-small cell lung cancer in smokers and never-smokers.

Govindan R, Ding L, Griffith M, Subramanian J, Dees ND, Kanchi KL, Maher CA, Fulton R, Fulton L, Wallis J, Chen K, Walker J, McDonald S, Bose R, Ornitz D, Xiong D, You M, Dooling DJ, Watson M, Mardis ER, Wilson RK.

Cell. 2012 Sep 14;150(6):1121-34. doi: 10.1016/j.cell.2012.08.024.


A high-dimensional, deep-sequencing study of lung adenocarcinoma in female never-smokers.

Kim SC, Jung Y, Park J, Cho S, Seo C, Kim J, Kim P, Park J, Seo J, Kim J, Park S, Jang I, Kim N, Yang JO, Lee B, Rho K, Jung Y, Keum J, Lee J, Han J, Kang S, Bae S, Choi SJ, Kim S, Lee JE, Kim W, Kim J, Lee S.

PLoS One. 2013;8(2):e55596. doi: 10.1371/journal.pone.0055596. Epub 2013 Feb 6.


Molecular profiles of non-small cell lung cancers in cigarette smoking and never-smoking patients.

Szymanowska-Narloch A, Jassem E, Skrzypski M, Muley T, Meister M, Dienemann H, Taron M, Rosell R, Rzepko R, Jarząb M, Marjański T, Pawłowski R, Rzyman W, Jassem J.

Adv Med Sci. 2013;58(2):196-206. doi: 10.2478/ams-2013-0025.


Genomic Characterization of Non-Small-Cell Lung Cancer in African Americans by Targeted Massively Parallel Sequencing.

Araujo LH, Timmers C, Bell EH, Shilo K, Lammers PE, Zhao W, Natarajan TG, Miller CJ, Zhang J, Yilmaz AS, Liu T, Coombes K, Amann J, Carbone DP.

J Clin Oncol. 2015 Jun 10;33(17):1966-73. doi: 10.1200/JCO.2014.59.2444. Epub 2015 Apr 27.


Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation.

Vigneswaran J, Tan YH, Murgu SD, Won BM, Patton KA, Villaflor VM, Hoffman PC, Hensing T, Hogarth DK, Malik R, MacMahon H, Mueller J, Simon CA, Vigneswaran WT, Wigfield CH, Ferguson MK, Husain AN, Vokes EE, Salgia R.

Oncotarget. 2016 Apr 5;7(14):18876-86. doi: 10.18632/oncotarget.7739.


Identification of enriched driver gene alterations in subgroups of non-small cell lung cancer patients based on histology and smoking status.

An SJ, Chen ZH, Su J, Zhang XC, Zhong WZ, Yang JJ, Zhou Q, Yang XN, Huang L, Guan JL, Nie Q, Yan HH, Mok TS, Wu YL.

PLoS One. 2012;7(6):e40109. doi: 10.1371/journal.pone.0040109. Epub 2012 Jun 29.


Loss of Fhit is frequent in stage I non-small cell lung cancer and in the lungs of chronic smokers.

Tseng JE, Kemp BL, Khuri FR, Kurie JM, Lee JS, Zhou X, Liu D, Hong WK, Mao L.

Cancer Res. 1999 Oct 1;59(19):4798-803.


Molecular genetics of small cell lung carcinoma.

Wistuba II, Gazdar AF, Minna JD.

Semin Oncol. 2001 Apr;28(2 Suppl 4):3-13. Review.


Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS-Mutant Lung Adenocarcinoma.

Calles A, Sholl LM, Rodig SJ, Pelton AK, Hornick JL, Butaney M, Lydon C, Dahlberg SE, Oxnard GR, Jackman DM, Jänne PA.

Clin Cancer Res. 2015 Jun 15;21(12):2851-60. doi: 10.1158/1078-0432.CCR-14-3112. Epub 2015 Mar 3.


Spectrum of oncogenic driver mutations in lung adenocarcinomas from East Asian never smokers.

Li C, Fang R, Sun Y, Han X, Li F, Gao B, Iafrate AJ, Liu XY, Pao W, Chen H, Ji H.

PLoS One. 2011;6(11):e28204. doi: 10.1371/journal.pone.0028204. Epub 2011 Nov 30.


Success and failure rates of tumor genotyping techniques in routine pathological samples with non-small-cell lung cancer.

Vanderlaan PA, Yamaguchi N, Folch E, Boucher DH, Kent MS, Gangadharan SP, Majid A, Goldstein MA, Huberman MS, Kocher ON, Costa DB.

Lung Cancer. 2014 Apr;84(1):39-44. doi: 10.1016/j.lungcan.2014.01.013. Epub 2014 Jan 28.


Rare mutations in non-small-cell lung cancer.

D'Arcangelo M, D'Incecco A, Cappuzzo F.

Future Oncol. 2013 May;9(5):699-711. doi: 10.2217/fon.13.16. Review.


Distribution of p53 and K-ras mutations in human lung cancer tissues.

Gao HG, Chen JK, Stewart J, Song B, Rayappa C, Whong WZ, Ong T.

Carcinogenesis. 1997 Mar;18(3):473-8.


MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers.

Seike M, Goto A, Okano T, Bowman ED, Schetter AJ, Horikawa I, Mathe EA, Jen J, Yang P, Sugimura H, Gemma A, Kudoh S, Croce CM, Harris CC.

Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12085-90. doi: 10.1073/pnas.0905234106. Epub 2009 Jul 13.


Never smokers with lung cancer: analysis of genetic variants.

Xiao H, Ding J, Gao S, Yang S, Huang Y.

Asian Pac J Cancer Prev. 2011;12(10):2807-9.


XPC mRNA level may predict relapse in never-smokers with non-small cell lung cancers.

Yeh KT, Wu YH, Lee MC, Wang L, Li CT, Chen CY, Lee H.

Ann Surg Oncol. 2012 Mar;19(3):734-42. doi: 10.1245/s10434-011-1992-9. Epub 2011 Aug 23.


EGFR, ERBB2, and KRAS mutations in Korean non-small cell lung cancer patients.

Bae NC, Chae MH, Lee MH, Kim KM, Lee EB, Kim CH, Park TI, Han SB, Jheon S, Jung TH, Park JY.

Cancer Genet Cytogenet. 2007 Mar;173(2):107-13.


Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers.

Woenckhaus M, Klein-Hitpass L, Grepmeier U, Merk J, Pfeifer M, Wild P, Bettstetter M, Wuensch P, Blaszyk H, Hartmann A, Hofstaedter F, Dietmaier W.

J Pathol. 2006 Oct;210(2):192-204.


Non-small cell lung cancer in never smokers as a representative 'non-smoking-associated lung cancer': epidemiology and clinical features.

Yano T, Haro A, Shikada Y, Maruyama R, Maehara Y.

Int J Clin Oncol. 2011 Aug;16(4):287-93. doi: 10.1007/s10147-010-0160-8. Epub 2011 May 13. Review.


Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer.

Hirao T, Nelson HH, Ashok TD, Wain JC, Mark EJ, Christiani DC, Wiencke JK, Kelsey KT.

Cancer Res. 2001 Jan 15;61(2):612-5.

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