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Items: 1 to 20 of 106


Gene location and DNA density determine transcription factor distributions in Escherichia coli.

Kuhlman TE, Cox EC.

Mol Syst Biol. 2012;8:610. doi: 10.1038/msb.2012.42.


Tracking Low-Copy Transcription Factors in Living Bacteria: The Case of the lac Repressor.

Garza de Leon F, Sellars L, Stracy M, Busby SJ, Kapanidis AN.

Biophys J. 2017 Apr 11;112(7):1316-1327. doi: 10.1016/j.bpj.2017.02.028.


Quantitative influence of macromolecular crowding on gene regulation kinetics.

Tabaka M, Kalwarczyk T, Hołyst R.

Nucleic Acids Res. 2014 Jan;42(2):727-38. doi: 10.1093/nar/gkt907. Epub 2013 Oct 10.


DNA-binding-protein inhomogeneity in E. coli modeled as biphasic facilitated diffusion.

Kuhlman TE, Cox EC.

Phys Rev E Stat Nonlin Soft Matter Phys. 2013 Aug;88(2):022701. Epub 2013 Aug 1.


DNA Internal Motion Likely Accelerates Protein Target Search in a Packed Nucleoid.

Chow E, Skolnick J.

Biophys J. 2017 Jun 6;112(11):2261-2270. doi: 10.1016/j.bpj.2017.04.049.


The effect of LacI autoregulation on the performance of the lactose utilization system in Escherichia coli.

Semsey S, Jauffred L, Csiszovszki Z, Erdossy J, Stéger V, Hansen S, Krishna S.

Nucleic Acids Res. 2013 Jul;41(13):6381-90. doi: 10.1093/nar/gkt351. Epub 2013 May 8.


Mutagenesis in the lacI gene target of E. coli: improved analysis for lacI(d) and lacO mutants.

Swerdlow SJ, Schaaper RM.

Mutat Res. 2014 Dec;770:79-84. doi: 10.1016/j.mrfmmm.2014.09.004. Epub 2014 Sep 27.


Quantitation of the DNA tethering effect in long-range DNA looping in vivo and in vitro using the Lac and λ repressors.

Priest DG, Cui L, Kumar S, Dunlap DD, Dodd IB, Shearwin KE.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):349-54. doi: 10.1073/pnas.1317817111. Epub 2013 Dec 16.


DNA supercoiling, a critical signal regulating the basal expression of the lac operon in Escherichia coli.

Fulcrand G, Dages S, Zhi X, Chapagain P, Gerstman BS, Dunlap D, Leng F.

Sci Rep. 2016 Jan 14;6:19243. doi: 10.1038/srep19243.


Engineering an allosteric transcription factor to respond to new ligands.

Taylor ND, Garruss AS, Moretti R, Chan S, Arbing MA, Cascio D, Rogers JK, Isaacs FJ, Kosuri S, Baker D, Fields S, Church GM, Raman S.

Nat Methods. 2016 Feb;13(2):177-83. doi: 10.1038/nmeth.3696. Epub 2015 Dec 21.


Novel insights from hybrid LacI/GalR proteins: family-wide functional attributes and biologically significant variation in transcription repression.

Meinhardt S, Manley MW Jr, Becker NA, Hessman JA, Maher LJ 3rd, Swint-Kruse L.

Nucleic Acids Res. 2012 Nov;40(21):11139-54. doi: 10.1093/nar/gks806. Epub 2012 Sep 10.


In vivo tests of thermodynamic models of transcription repressor function.

Tungtur S, Skinner H, Zhan H, Swint-Kruse L, Beckett D.

Biophys Chem. 2011 Nov;159(1):142-51. doi: 10.1016/j.bpc.2011.06.005. Epub 2011 Jun 15.


Mutation spectrum in the lacI gene, induced by gamma-radiation in aqueous solution under oxic conditions.

Wijker CA, Wientjes NM, Lafleur VM.

Mutat Res. 1998 Jul 17;403(1-2):137-47.


The lac repressor displays facilitated diffusion in living cells.

Hammar P, Leroy P, Mahmutovic A, Marklund EG, Berg OG, Elf J.

Science. 2012 Jun 22;336(6088):1595-8. doi: 10.1126/science.1221648.


Protein distributions from a stochastic model of the lac operon of E. coli with DNA looping: analytical solution and comparison with experiments.

Choudhary K, Oehler S, Narang A.

PLoS One. 2014 Jul 23;9(7):e102580. doi: 10.1371/journal.pone.0102580. eCollection 2014.


Comparative genomics of CytR, an unusual member of the LacI family of transcription factors.

Sernova NV, Gelfand MS.

PLoS One. 2012;7(9):e44194. doi: 10.1371/journal.pone.0044194. Epub 2012 Sep 24.


Model of SOS-induced mutagenesis in bacteria Escherichia coli under ultraviolet irradiation.

Belov OV, Krasavin EA, Parkhomenko AY.

J Theor Biol. 2009 Dec 7;261(3):388-95. doi: 10.1016/j.jtbi.2009.08.016. Epub 2009 Aug 21.


LacI-DNA-IPTG loops: equilibria among conformations by single-molecule FRET.

Goodson KA, Wang Z, Haeusler AR, Kahn JD, English DS.

J Phys Chem B. 2013 Apr 25;117(16):4713-22. doi: 10.1021/jp308930c. Epub 2013 Feb 13.


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