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Items: 1 to 20 of 152


Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations.

Pinter SF, Sadreyev RI, Yildirim E, Jeon Y, Ohsumi TK, Borowsky M, Lee JT.

Genome Res. 2012 Oct;22(10):1864-76. doi: 10.1101/gr.133751.111.


High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation.

Simon MD, Pinter SF, Fang R, Sarma K, Rutenberg-Schoenberg M, Bowman SK, Kesner BA, Maier VK, Kingston RE, Lee JT.

Nature. 2013 Dec 19;504(7480):465-9. doi: 10.1038/nature12719.


High-resolution analysis of epigenetic changes associated with X inactivation.

Marks H, Chow JC, Denissov S, Fran├žoijs KJ, Brockdorff N, Heard E, Stunnenberg HG.

Genome Res. 2009 Aug;19(8):1361-73. doi: 10.1101/gr.092643.109.


Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome.

da Rocha ST, Boeva V, Escamilla-Del-Arenal M, Ancelin K, Granier C, Matias NR, Sanulli S, Chow J, Schulz E, Picard C, Kaneko S, Helin K, Reinberg D, Stewart AF, Wutz A, Margueron R, Heard E.

Mol Cell. 2014 Jan 23;53(2):301-16. doi: 10.1016/j.molcel.2014.01.002.


Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome.

Zhao J, Sun BK, Erwin JA, Song JJ, Lee JT.

Science. 2008 Oct 31;322(5902):750-6. doi: 10.1126/science.1163045.


The Xist RNA-PRC2 complex at 20-nm resolution reveals a low Xist stoichiometry and suggests a hit-and-run mechanism in mouse cells.

Sunwoo H, Wu JY, Lee JT.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4216-25. doi: 10.1073/pnas.1503690112.


ATRX directs binding of PRC2 to Xist RNA and Polycomb targets.

Sarma K, Cifuentes-Rojas C, Ergun A, Del Rosario A, Jeon Y, White F, Sadreyev R, Lee JT.

Cell. 2014 Nov 6;159(4):869-83. doi: 10.1016/j.cell.2014.10.019. Erratum in: Cell. 2015 Jan 29;160(3):568-9. Cell. 2014 Nov 20;159(5):1228.


Structural organization of the inactive X chromosome in the mouse.

Giorgetti L, Lajoie BR, Carter AC, Attia M, Zhan Y, Xu J, Chen CJ, Kaplan N, Chang HY, Heard E, Dekker J.

Nature. 2016 Jul 28;535(7613):575-9.


Guided by RNAs: X-inactivation as a model for lncRNA function.

Froberg JE, Yang L, Lee JT.

J Mol Biol. 2013 Oct 9;425(19):3698-706. doi: 10.1016/j.jmb.2013.06.031. Review.


The making of a Barr body: the mosaic of factors that eXIST on the mammalian inactive X chromosome.

Dixon-McDougall T, Brown C.

Biochem Cell Biol. 2016 Feb;94(1):56-70. doi: 10.1139/bcb-2015-0016. Review.


Live cell imaging of the nascent inactive X chromosome during the early differentiation process of naive ES cells towards epiblast stem cells.

Guyochin A, Maenner S, Chu ET, Hentati A, Attia M, Avner P, Clerc P.

PLoS One. 2014 Dec 29;9(12):e116109. doi: 10.1371/journal.pone.0116109.


Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals.

Chaumeil J, Waters PD, Koina E, Gilbert C, Robinson TJ, Graves JA.

PLoS One. 2011 Apr 25;6(4):e19040. doi: 10.1371/journal.pone.0019040.


Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy.

Cerase A, Smeets D, Tang YA, Gdula M, Kraus F, Spivakov M, Moindrot B, Leleu M, Tattermusch A, Demmerle J, Nesterova TB, Green C, Otte AP, Schermelleh L, Brockdorff N.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2235-40. doi: 10.1073/pnas.1312951111.


Regulation of X-chromosome inactivation in development in mice and humans.

Goto T, Monk M.

Microbiol Mol Biol Rev. 1998 Jun;62(2):362-78. Review.


Xist localization and function: new insights from multiple levels.

Cerase A, Pintacuda G, Tattermusch A, Avner P.

Genome Biol. 2015 Aug 15;16:166. doi: 10.1186/s13059-015-0733-y. Review.


The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation.

Tian D, Sun S, Lee JT.

Cell. 2010 Oct 29;143(3):390-403. doi: 10.1016/j.cell.2010.09.049.


YY1 tethers Xist RNA to the inactive X nucleation center.

Jeon Y, Lee JT.

Cell. 2011 Jul 8;146(1):119-33. doi: 10.1016/j.cell.2011.06.026.


The trans-activator RNF12 and cis-acting elements effectuate X chromosome inactivation independent of X-pairing.

Barakat TS, Loos F, van Staveren S, Myronova E, Ghazvini M, Grootegoed JA, Gribnau J.

Mol Cell. 2014 Mar 20;53(6):965-78. doi: 10.1016/j.molcel.2014.02.006.

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