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Items: 1 to 20 of 122

1.

The molecular basis for substrate specificity of the nuclear NIPP1:PP1 holoenzyme.

O'Connell N, Nichols SR, Heroes E, Beullens M, Bollen M, Peti W, Page R.

Structure. 2012 Oct 10;20(10):1746-56. doi: 10.1016/j.str.2012.08.003. Epub 2012 Aug 30.

3.

Nuclear inhibitor of protein phosphatase-1 (NIPP1) directs protein phosphatase-1 (PP1) to dephosphorylate the U2 small nuclear ribonucleoprotein particle (snRNP) component, spliceosome-associated protein 155 (Sap155).

Tanuma N, Kim SE, Beullens M, Tsubaki Y, Mitsuhashi S, Nomura M, Kawamura T, Isono K, Koseki H, Sato M, Bollen M, Kikuchi K, Shima H.

J Biol Chem. 2008 Dec 19;283(51):35805-14. doi: 10.1074/jbc.M805468200. Epub 2008 Oct 8.

4.

Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1.

Ammosova T, Platonov M, Yedavalli VR, Obukhov Y, Gordeuk VR, Jeang KT, Kovalskyy D, Nekhai S.

PLoS One. 2012;7(6):e39481. doi: 10.1371/journal.pone.0039481. Epub 2012 Jun 29.

5.

Degeneracy and function of the ubiquitous RVXF motif that mediates binding to protein phosphatase-1.

Wakula P, Beullens M, Ceulemans H, Stalmans W, Bollen M.

J Biol Chem. 2003 May 23;278(21):18817-23. Epub 2003 Mar 25.

6.

NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes.

Minnebo N, Görnemann J, O'Connell N, Van Dessel N, Derua R, Vermunt MW, Page R, Beullens M, Peti W, Van Eynde A, Bollen M.

Nucleic Acids Res. 2013 Jan;41(2):842-54. doi: 10.1093/nar/gks1255. Epub 2012 Dec 13.

7.

Protein phosphatase PP1-NIPP1 activates mesenchymal genes in HeLa cells.

Van Dessel N, Boens S, Lesage B, Winkler C, Görnemann J, Van Eynde A, Bollen M.

FEBS Lett. 2015 May 22;589(12):1314-21. doi: 10.1016/j.febslet.2015.04.017. Epub 2015 Apr 20.

8.

Interactor-mediated nuclear translocation and retention of protein phosphatase-1.

Lesage B, Beullens M, Nuytten M, Van Eynde A, Keppens S, Himpens B, Bollen M.

J Biol Chem. 2004 Dec 31;279(53):55978-84. Epub 2004 Oct 22.

9.

NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry.

Boudrez A, Beullens M, Groenen P, Van Eynde A, Vulsteke V, Jagiello I, Murray M, Krainer AR, Stalmans W, Bollen M.

J Biol Chem. 2000 Aug 18;275(33):25411-7.

10.

Nuclear and subnuclear targeting sequences of the protein phosphatase-1 regulator NIPP1.

Jagiello I, Van Eynde A, Vulsteke V, Beullens M, Boudrez A, Keppens S, Stalmans W, Bollen M.

J Cell Sci. 2000 Nov;113 Pt 21:3761-8.

12.

Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code.

Choy MS, Hieke M, Kumar GS, Lewis GR, Gonzalez-DeWhitt KR, Kessler RP, Stein BJ, Hessenberger M, Nairn AC, Peti W, Page R.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4097-102. doi: 10.1073/pnas.1317395111. Epub 2014 Mar 3.

13.

Nuclear organisation of NIPP1, a regulatory subunit of protein phosphatase 1 that associates with pre-mRNA splicing factors.

Trinkle-Mulcahy L, Ajuh P, Prescott A, Claverie-Martin F, Cohen S, Lamond AI, Cohen P.

J Cell Sci. 1999 Jan;112 ( Pt 2):157-68.

14.
15.

A role for PP1/NIPP1 in steering migration of human cancer cells.

Martin-Granados C, Prescott AR, Van Dessel N, Van Eynde A, Arocena M, Klaska IP, Görnemann J, Beullens M, Bollen M, Forrester JV, McCaig CD.

PLoS One. 2012;7(7):e40769. doi: 10.1371/journal.pone.0040769. Epub 2012 Jul 16.

16.

Importance of a surface hydrophobic pocket on protein phosphatase-1 catalytic subunit in recognizing cellular regulators.

Gibbons JA, Weiser DC, Shenolikar S.

J Biol Chem. 2005 Apr 22;280(16):15903-11. Epub 2005 Feb 9.

17.

Structural basis for regulation of protein phosphatase 1 by inhibitor-2.

Hurley TD, Yang J, Zhang L, Goodwin KD, Zou Q, Cortese M, Dunker AK, DePaoli-Roach AA.

J Biol Chem. 2007 Sep 28;282(39):28874-83. Epub 2007 Jul 18.

18.

Structural basis of protein phosphatase 1 regulation.

Terrak M, Kerff F, Langsetmo K, Tao T, Dominguez R.

Nature. 2004 Jun 17;429(6993):780-4. Epub 2004 May 26.

PMID:
15164081
19.

Conversion of protein phosphatase 1 catalytic subunit to a Mn(2+)-dependent enzyme impairs its regulation by inhibitor 1.

Endo S, Connor JH, Forney B, Zhang L, Ingebritsen TS, Lee EY, Shenolikar S.

Biochemistry. 1997 Jun 10;36(23):6986-92.

PMID:
9188695
20.

PNUTS, a protein phosphatase 1 (PP1) nuclear targeting subunit. Characterization of its PP1- and RNA-binding domains and regulation by phosphorylation.

Kim YM, Watanabe T, Allen PB, Kim YM, Lee SJ, Greengard P, Nairn AC, Kwon YG.

J Biol Chem. 2003 Apr 18;278(16):13819-28. Epub 2003 Feb 6.

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