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Genome-wide analysis of germline signaling genes regulating longevity and innate immunity in the nematode Pristionchus pacificus.

Rae R, Sinha A, Sommer RJ.

PLoS Pathog. 2012;8(8):e1002864. doi: 10.1371/journal.ppat.1002864. Epub 2012 Aug 9.


A functional genomic screen for evolutionarily conserved genes required for lifespan and immunity in germline-deficient C. elegans.

Sinha A, Rae R.

PLoS One. 2014 Aug 5;9(8):e101970. doi: 10.1371/journal.pone.0101970. eCollection 2014.


System wide analysis of the evolution of innate immunity in the nematode model species Caenorhabditis elegans and Pristionchus pacificus.

Sinha A, Rae R, Iatsenko I, Sommer RJ.

PLoS One. 2012;7(9):e44255. doi: 10.1371/journal.pone.0044255. Epub 2012 Sep 28.


The cGMP signaling pathway affects feeding behavior in the necromenic nematode Pristionchus pacificus.

Kroetz SM, Srinivasan J, Yaghoobian J, Sternberg PW, Hong RL.

PLoS One. 2012;7(4):e34464. doi: 10.1371/journal.pone.0034464. Epub 2012 Apr 26.


Divergent gene expression in the conserved dauer stage of the nematodes Pristionchus pacificus and Caenorhabditis elegans.

Sinha A, Sommer RJ, Dieterich C.

BMC Genomics. 2012 Jun 19;13:254. doi: 10.1186/1471-2164-13-254.


The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity.

Alper S, McElwee MK, Apfeld J, Lackford B, Freedman JH, Schwartz DA.

J Biol Chem. 2010 Jan 15;285(3):1822-8. doi: 10.1074/jbc.M109.057323. Epub 2009 Nov 18.


The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism.

Dieterich C, Clifton SW, Schuster LN, Chinwalla A, Delehaunty K, Dinkelacker I, Fulton L, Fulton R, Godfrey J, Minx P, Mitreva M, Roeseler W, Tian H, Witte H, Yang SP, Wilson RK, Sommer RJ.

Nat Genet. 2008 Oct;40(10):1193-8. doi: 10.1038/ng.227. Epub 2008 Sep 21.


The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in C. elegans.

Evans EA, Chen WC, Tan MW.

Aging Cell. 2008 Dec;7(6):879-93. doi: 10.1111/j.1474-9726.2008.00435.x. Epub 2008 Sep 8.


Pristionchus pacificus daf-16 is essential for dauer formation but dispensable for mouth form dimorphism.

Ogawa A, Bento G, Bartelmes G, Dieterich C, Sommer RJ.

Development. 2011 Apr;138(7):1281-4. doi: 10.1242/dev.058909. Epub 2011 Feb 24.


Isolation of naturally associated bacteria of necromenic Pristionchus nematodes and fitness consequences.

Rae R, Riebesell M, Dinkelacker I, Wang Q, Herrmann M, Weller AM, Dieterich C, Sommer RJ.

J Exp Biol. 2008 Jun;211(Pt 12):1927-36. doi: 10.1242/jeb.014944.


A subset of naturally isolated Bacillus strains show extreme virulence to the free-living nematodes Caenorhabditis elegans and Pristionchus pacificus.

Rae R, Iatsenko I, Witte H, Sommer RJ.

Environ Microbiol. 2010 Nov;12(11):3007-21. doi: 10.1111/j.1462-2920.2010.02278.x.


Comparative transcriptomics of the nematode gut identifies global shifts in feeding mode and pathogen susceptibility.

Lightfoot JW, Chauhan VM, Aylott JW, Rödelsperger C.

BMC Res Notes. 2016 Mar 5;9:142. doi: 10.1186/s13104-016-1886-9.


The importance of being regular: Caenorhabditis elegans and Pristionchus pacificus defecation mutants are hypersusceptible to bacterial pathogens.

Rae R, Witte H, Rödelsperger C, Sommer RJ.

Int J Parasitol. 2012 Jul;42(8):747-53. doi: 10.1016/j.ijpara.2012.05.005. Epub 2012 Jun 13.


Genome-wide analysis of trans-splicing in the nematode Pristionchus pacificus unravels conserved gene functions for germline and dauer development in divergent operons.

Sinha A, Langnick C, Sommer RJ, Dieterich C.

RNA. 2014 Sep;20(9):1386-97. doi: 10.1261/rna.041954.113. Epub 2014 Jul 11.


A pathway that links reproductive status to lifespan in Caenorhabditis elegans.

Kenyon C.

Ann N Y Acad Sci. 2010 Aug;1204:156-62. doi: 10.1111/j.1749-6632.2010.05640.x. Review.


Distinct activities of the germline and somatic reproductive tissues in the regulation of Caenorhabditis elegans' longevity.

Yamawaki TM, Arantes-Oliveira N, Berman JR, Zhang P, Kenyon C.

Genetics. 2008 Jan;178(1):513-26. doi: 10.1534/genetics.107.083253.


Signals from the reproductive system regulate the lifespan of C. elegans.

Hsin H, Kenyon C.

Nature. 1999 May 27;399(6734):362-6.


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