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Items: 1 to 20 of 289

1.

Transition from colitis to cancer: high Wnt activity sustains the tumor-initiating potential of colon cancer stem cell precursors.

Shenoy AK, Fisher RC, Butterworth EA, Pi L, Chang LJ, Appelman HD, Chang M, Scott EW, Huang EH.

Cancer Res. 2012 Oct 1;72(19):5091-100. doi: 10.1158/0008-5472.CAN-12-1806. Epub 2012 Aug 17.

2.

L1-mediated colon cancer cell metastasis does not require changes in EMT and cancer stem cell markers.

Gavert N, Vivanti A, Hazin J, Brabletz T, Ben-Ze'ev A.

Mol Cancer Res. 2011 Jan;9(1):14-24. doi: 10.1158/1541-7786.MCR-10-0406. Epub 2010 Dec 1.

3.

Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer.

Carpentino JE, Hynes MJ, Appelman HD, Zheng T, Steindler DA, Scott EW, Huang EH.

Cancer Res. 2009 Oct 15;69(20):8208-15. doi: 10.1158/0008-5472.CAN-09-1132. Epub 2009 Oct 6.

4.

Induction of the stem-like cell regulator CD44 by Rho kinase inhibition contributes to the maintenance of colon cancer-initiating cells.

Ohata H, Ishiguro T, Aihara Y, Sato A, Sakai H, Sekine S, Taniguchi H, Akasu T, Fujita S, Nakagama H, Okamoto K.

Cancer Res. 2012 Oct 1;72(19):5101-10. doi: 10.1158/0008-5472.CAN-11-3812. Epub 2012 Sep 20.

5.

A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations.

Buchert M, Rohde F, Eissmann M, Tebbutt N, Williams B, Tan CW, Owen A, Hirokawa Y, Gnann A, Orend G, Orner G, Dashwood RH, Heath JK, Ernst M, Janssen KP.

Dis Model Mech. 2015 Nov;8(11):1361-73. doi: 10.1242/dmm.019844. Epub 2015 Aug 6.

6.

HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression.

Li Y, Bavarva JH, Wang Z, Guo J, Qian C, Thibodeau SN, Golemis EA, Liu W.

Oncogene. 2011 Jun 9;30(23):2633-43. doi: 10.1038/onc.2010.632. Epub 2011 Feb 14.

7.

β-Catenin promotes colitis and colon cancer through imprinting of proinflammatory properties in T cells.

Keerthivasan S, Aghajani K, Dose M, Molinero L, Khan MW, Venkateswaran V, Weber C, Emmanuel AO, Sun T, Bentrem DJ, Mulcahy M, Keshavarzian A, Ramos EM, Blatner N, Khazaie K, Gounari F.

Sci Transl Med. 2014 Feb 26;6(225):225ra28. doi: 10.1126/scitranslmed.3007607.

8.

The Wnt/β-catenin pathway regulates self-renewal of cancer stem-like cells in human gastric cancer.

Cai C, Zhu X.

Mol Med Rep. 2012 May;5(5):1191-6. doi: 10.3892/mmr.2012.802. Epub 2012 Feb 21.

PMID:
22367735
9.

MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway.

Hsieh IS, Chang KC, Tsai YT, Ke JY, Lu PJ, Lee KH, Yeh SD, Hong TM, Chen YL.

Carcinogenesis. 2013 Mar;34(3):530-8. doi: 10.1093/carcin/bgs371. Epub 2012 Nov 26.

PMID:
23188675
10.

Epithelial-mesenchymal transition associates with maintenance of stemness in spheroid-derived stem-like colon cancer cells.

Han XY, Wei B, Fang JF, Zhang S, Zhang FC, Zhang HB, Lan TY, Lu HQ, Wei HB.

PLoS One. 2013 Sep 9;8(9):e73341. doi: 10.1371/journal.pone.0073341. eCollection 2013.

11.

Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells.

Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, Yu Y, Clouthier SG, Schwartz SJ, Wicha MS, Sun D.

Clin Cancer Res. 2010 May 1;16(9):2580-90. doi: 10.1158/1078-0432.CCR-09-2937. Epub 2010 Apr 13.

12.

LGR5 Promotes Breast Cancer Progression and Maintains Stem-Like Cells Through Activation of Wnt/β-Catenin Signaling.

Yang L, Tang H, Kong Y, Xie X, Chen J, Song C, Liu X, Ye F, Li N, Wang N, Xie X.

Stem Cells. 2015 Oct;33(10):2913-24. doi: 10.1002/stem.2083. Epub 2015 Jul 14.

13.

Protein kinase C ζ is a positive modulator of canonical Wnt signaling pathway in tumoral colon cell lines.

Luna-Ulloa LB, Hernández-Maqueda JG, Santoyo-Ramos P, Castañeda-Patlán MC, Robles-Flores M.

Carcinogenesis. 2011 Nov;32(11):1615-24. doi: 10.1093/carcin/bgr190. Epub 2011 Aug 22.

PMID:
21859831
14.

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.

Sullivan JP, Spinola M, Dodge M, Raso MG, Behrens C, Gao B, Schuster K, Shao C, Larsen JE, Sullivan LA, Honorio S, Xie Y, Scaglioni PP, DiMaio JM, Gazdar AF, Shay JW, Wistuba II, Minna JD.

Cancer Res. 2010 Dec 1;70(23):9937-48. doi: 10.1158/0008-5472.CAN-10-0881. Epub 2010 Nov 30.

15.

Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma.

Cheng Y, Cheung AK, Ko JM, Phoon YP, Chiu PM, Lo PH, Waterman ML, Lung ML.

BMC Cell Biol. 2013 Sep 27;14:44. doi: 10.1186/1471-2121-14-44.

16.

Phosphoinositide 3-kinase signaling mediates beta-catenin activation in intestinal epithelial stem and progenitor cells in colitis.

Lee G, Goretsky T, Managlia E, Dirisina R, Singh AP, Brown JB, May R, Yang GY, Ragheb JW, Evers BM, Weber CR, Turner JR, He XC, Katzman RB, Li L, Barrett TA.

Gastroenterology. 2010 Sep;139(3):869-81, 881.e1-9. doi: 10.1053/j.gastro.2010.05.037. Epub 2010 May 24.

17.

miR-942 promotes cancer stem cell-like traits in esophageal squamous cell carcinoma through activation of Wnt/β-catenin signalling pathway.

Ge C, Wu S, Wang W, Liu Z, Zhang J, Wang Z, Li R, Zhang Z, Li Z, Dong S, Wang Y, Xue Y, Yang J, Tan Q, Wang Z, Song X.

Oncotarget. 2015 May 10;6(13):10964-77.

18.
19.

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/β-catenin pathway.

Li D, Liu W, Wang X, Wu J, Quan W, Yao Y, Bals R, Ji S, Wu K, Guo J, Wan H.

Oncotarget. 2015 Feb 20;6(5):2939-50.

20.

Notch and Wnt/β-catenin signaling pathway play important roles in activating liver cancer stem cells.

Wang R, Sun Q, Wang P, Liu M, Xiong S, Luo J, Huang H, Du Q, Geller DA, Cheng B.

Oncotarget. 2016 Feb 2;7(5):5754-68. doi: 10.18632/oncotarget.6805.

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