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Items: 1 to 20 of 115

1.

Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling.

Dühren-von Minden M, Übelhart R, Schneider D, Wossning T, Bach MP, Buchner M, Hofmann D, Surova E, Follo M, Köhler F, Wardemann H, Zirlik K, Veelken H, Jumaa H.

Nature. 2012 Sep 13;489(7415):309-12. doi: 10.1038/nature11309.

PMID:
22885698
2.

Chronic lymphocytic leukemia: a tale of one or two signals?

Chiorazzi N, Efremov DG.

Cell Res. 2013 Feb;23(2):182-5. doi: 10.1038/cr.2012.152.

3.

Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells.

Binder M, Léchenne B, Ummanni R, Scharf C, Balabanov S, Trusch M, Schlüter H, Braren I, Spillner E, Trepel M.

PLoS One. 2010 Dec 30;5(12):e15992. doi: 10.1371/journal.pone.0015992.

4.

Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia.

Tobin G, Thunberg U, Karlsson K, Murray F, Laurell A, Willander K, Enblad G, Merup M, Vilpo J, Juliusson G, Sundström C, Söderberg O, Roos G, Rosenquist R.

Blood. 2004 Nov 1;104(9):2879-85.

5.

Remarkably similar antigen receptors among a subset of patients with chronic lymphocytic leukemia.

Ghiotto F, Fais F, Valetto A, Albesiano E, Hashimoto S, Dono M, Ikematsu H, Allen SL, Kolitz J, Rai KR, Nardini M, Tramontano A, Ferrarini M, Chiorazzi N.

J Clin Invest. 2004 Apr;113(7):1008-16.

6.

Two types of BCR interactions are positively selected during leukemia development in the Eμ-TCL1 transgenic mouse model of CLL.

Iacovelli S, Hug E, Bennardo S, Duehren-von Minden M, Gobessi S, Rinaldi A, Suljagic M, Bilbao D, Bolasco G, Eckl-Dorna J, Niederberger V, Autore F, Sica S, Laurenti L, Wang H, Cornall RJ, Clarke SH, Croce CM, Bertoni F, Jumaa H, Efremov DG.

Blood. 2015 Mar 5;125(10):1578-88. doi: 10.1182/blood-2014-07-587790.

7.
8.

Autoantigenic targets of B-cell receptors derived from chronic lymphocytic leukemias bind to and induce proliferation of leukemic cells.

Zwick C, Fadle N, Regitz E, Kemele M, Stilgenbauer S, Bühler A, Pfreundschuh M, Preuss KD.

Blood. 2013 Jun 6;121(23):4708-17. doi: 10.1182/blood-2012-08-447904.

9.

B cell receptor signaling in chronic lymphocytic leukemia.

Burger JA, Chiorazzi N.

Trends Immunol. 2013 Dec;34(12):592-601. doi: 10.1016/j.it.2013.07.002. Review.

10.

Chronic lymphocytic leukaemia: could immunological tolerance mechanisms be the origin of lymphoid neoplasms?

García-Muñoz R, Llorente L.

Immunology. 2014 Aug;142(4):536-50. doi: 10.1111/imm.12285. Review.

11.

Basal Ca(2+) signaling is particularly increased in mutated chronic lymphocytic leukemia.

Muggen AF, Pillai SY, Kil LP, van Zelm MC, van Dongen JJ, Hendriks RW, Langerak AW.

Leukemia. 2015 Feb;29(2):321-8. doi: 10.1038/leu.2014.188.

PMID:
24917358
12.

Intraclonal cell expansion and selection driven by B cell receptor in chronic lymphocytic leukemia.

Colombo M, Cutrona G, Reverberi D, Fabris S, Neri A, Fabbi M, Quintana G, Quarta G, Ghiotto F, Fais F, Ferrarini M.

Mol Med. 2011;17(7-8):834-9. doi: 10.2119/molmed.2011.00047.

13.

Relevance of stereotyped B-cell receptors in the context of the molecular, cytogenetic and clinical features of chronic lymphocytic leukemia.

Maura F, Cutrona G, Fabris S, Colombo M, Tuana G, Agnelli L, Matis S, Lionetti M, Gentile M, Recchia AG, Di Raimondo F, Musolino C, Ilariucci F, Di Renzo N, Pesce E, Molica S, Federico M, Cortelezzi A, Morabito F, Ferrarini M, Neri A.

PLoS One. 2011;6(8):e24313. doi: 10.1371/journal.pone.0024313.

14.

Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity.

Hervé M, Xu K, Ng YS, Wardemann H, Albesiano E, Messmer BT, Chiorazzi N, Meffre E.

J Clin Invest. 2005 Jun;115(6):1636-43.

15.

Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study.

Bomben R, Dal Bo M, Capello D, Forconi F, Maffei R, Laurenti L, Rossi D, Del Principe MI, Zucchetto A, Bertoni F, Rossi FM, Bulian P, Cattarossi I, Ilariucci F, Sozzi E, Spina V, Zucca E, Degan M, Lauria F, Del Poeta G, Efremov DG, Marasca R, Gaidano G, Gattei V.

Br J Haematol. 2009 Feb;144(4):492-506. doi: 10.1111/j.1365-2141.2008.07469.x.

PMID:
19036101
16.

B-cell receptor epitope recognition correlates with the clinical course of chronic lymphocytic leukemia.

Binder M, Müller F, Jackst A, Léchenne B, Pantic M, Bacher U, Zu Eulenburg C, Veelken H, Mertelsmann R, Pasqualini R, Arap W, Trepel M.

Cancer. 2011 May 1;117(9):1891-900. doi: 10.1002/cncr.25755.

17.

Subjects with chronic lymphocytic leukaemia-like B-cell clones with stereotyped B-cell receptors frequently show MDS-associated phenotypes on myeloid cells.

Rodríguez-Caballero A, Henriques A, Criado I, Langerak AW, Matarraz S, López A, Balanzategui A, González M, Nieto WG, Cortesão E, Paiva A, Almeida J, Orfao A.

Br J Haematol. 2015 Jan;168(2):258-67. doi: 10.1111/bjh.13127.

PMID:
25252186
18.

B cell receptor and antigens in CLL.

Agathangelidis A, Ntoufa S, Stamatopoulos K.

Adv Exp Med Biol. 2013;792:1-24. doi: 10.1007/978-1-4614-8051-8_1. Review.

PMID:
24014290
19.

Immune thrombocytopenia in patients with chronic lymphocytic leukemia is associated with stereotyped B-cell receptors.

Visco C, Maura F, Tuana G, Agnelli L, Lionetti M, Fabris S, Novella E, Giaretta I, Reda G, Barcellini W, Baldini L, Neri A, Rodeghiero F, Cortelezzi A.

Clin Cancer Res. 2012 Apr 1;18(7):1870-8. doi: 10.1158/1078-0432.CCR-11-3019.

20.

B cell receptors in TCL1 transgenic mice resemble those of aggressive, treatment-resistant human chronic lymphocytic leukemia.

Yan XJ, Albesiano E, Zanesi N, Yancopoulos S, Sawyer A, Romano E, Petlickovski A, Efremov DG, Croce CM, Chiorazzi N.

Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11713-8.

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