Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 97

1.

Characterization of enzymes from Legionella pneumophila involved in reversible adenylylation of Rab1 protein.

Müller MP, Shkumatov AV, Oesterlin LK, Schoebel S, Goody PR, Goody RS, Itzen A.

J Biol Chem. 2012 Oct 12;287(42):35036-46. doi: 10.1074/jbc.M112.396861. Epub 2012 Aug 7.

2.

Legionella pneumophila SidD is a deAMPylase that modifies Rab1.

Tan Y, Luo ZQ.

Nature. 2011 Jul 6;475(7357):506-9. doi: 10.1038/nature10307.

3.

Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila.

Brombacher E, Urwyler S, Ragaz C, Weber SS, Kami K, Overduin M, Hilbi H.

J Biol Chem. 2009 Feb 20;284(8):4846-56. doi: 10.1074/jbc.M807505200. Epub 2008 Dec 17.

4.

The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b.

Müller MP, Peters H, Blümer J, Blankenfeldt W, Goody RS, Itzen A.

Science. 2010 Aug 20;329(5994):946-9. doi: 10.1126/science.1192276. Epub 2010 Jul 22.

5.

Reaction mechanism of adenylyltransferase DrrA from Legionella pneumophila elucidated by time-resolved fourier transform infrared spectroscopy.

Gavriljuk K, Schartner J, Itzen A, Goody RS, Gerwert K, Kötting C.

J Am Chem Soc. 2014 Jul 2;136(26):9338-45. doi: 10.1021/ja501496d. Epub 2014 Jun 20.

PMID:
24950229
6.

Structural insights into the dual nucleotide exchange and GDI displacement activity of SidM/DrrA.

Suh HY, Lee DW, Lee KH, Ku B, Choi SJ, Woo JS, Kim YG, Oh BH.

EMBO J. 2010 Jan 20;29(2):496-504. doi: 10.1038/emboj.2009.347. Epub 2009 Nov 26.

7.

Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA.

Zhu Y, Hu L, Zhou Y, Yao Q, Liu L, Shao F.

Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4699-704. doi: 10.1073/pnas.0914231107. Epub 2010 Feb 22.

8.

AMPylation is critical for Rab1 localization to vacuoles containing Legionella pneumophila.

Hardiman CA, Roy CR.

MBio. 2014 Feb 11;5(1):e01035-13. doi: 10.1128/mBio.01035-13.

9.

De-AMPylation unmasked: modulation of host membrane trafficking.

Ham H, Orth K.

Sci Signal. 2011 Oct 11;4(194):pe42. doi: 10.1126/scisignal.2002458. Review.

PMID:
21990428
10.

Modulation of Rab GTPase function by a protein phosphocholine transferase.

Mukherjee S, Liu X, Arasaki K, McDonough J, Galán JE, Roy CR.

Nature. 2011 Aug 7;477(7362):103-6. doi: 10.1038/nature10335.

11.

Structural insights into a unique Legionella pneumophila effector LidA recognizing both GDP and GTP bound Rab1 in their active state.

Cheng W, Yin K, Lu D, Li B, Zhu D, Chen Y, Zhang H, Xu S, Chai J, Gu L.

PLoS Pathog. 2012;8(3):e1002528. doi: 10.1371/journal.ppat.1002528. Epub 2012 Mar 1.

12.

Structural basis for Rab1 de-AMPylation by the Legionella pneumophila effector SidD.

Chen Y, Tascón I, Neunuebel MR, Pallara C, Brady J, Kinch LN, Fernández-Recio J, Rojas AL, Machner MP, Hierro A.

PLoS Pathog. 2013;9(5):e1003382. doi: 10.1371/journal.ppat.1003382. Epub 2013 May 16. Erratum in: PLoS Pathog. 2013;9(7). doi:10.1371/annotation/2b8e6418-2496-4ffb-b230-95d90b748086.

13.

The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor.

Murata T, Delprato A, Ingmundson A, Toomre DK, Lambright DG, Roy CR.

Nat Cell Biol. 2006 Sep;8(9):971-7. Epub 2006 Aug 13.

PMID:
16906144
14.

RabGDI displacement by DrrA from Legionella is a consequence of its guanine nucleotide exchange activity.

Schoebel S, Oesterlin LK, Blankenfeldt W, Goody RS, Itzen A.

Mol Cell. 2009 Dec 25;36(6):1060-72. doi: 10.1016/j.molcel.2009.11.014.

15.

The machinery at endoplasmic reticulum-plasma membrane contact sites contributes to spatial regulation of multiple Legionella effector proteins.

Hubber A, Arasaki K, Nakatsu F, Hardiman C, Lambright D, De Camilli P, Nagai H, Roy CR.

PLoS Pathog. 2014 Jul 3;10(7):e1004222. doi: 10.1371/journal.ppat.1004222. eCollection 2014 Jul.

16.

The taming of a Rab GTPase by Legionella pneumophila.

Neunuebel MR, Machner MP.

Small GTPases. 2012 Jan-Mar;3(1):28-33. doi: 10.4161/sgtp.18704.

17.

De-AMPylation of the small GTPase Rab1 by the pathogen Legionella pneumophila.

Neunuebel MR, Chen Y, Gaspar AH, Backlund PS Jr, Yergey A, Machner MP.

Science. 2011 Jul 22;333(6041):453-6. doi: 10.1126/science.1207193. Epub 2011 Jun 16.

18.

Legionella pneumophila proteins that regulate Rab1 membrane cycling.

Ingmundson A, Delprato A, Lambright DG, Roy CR.

Nature. 2007 Nov 15;450(7168):365-9. Epub 2007 Oct 21.

PMID:
17952054
19.

Legionella pneumophila LidA affects nucleotide binding and activity of the host GTPase Rab1.

Neunuebel MR, Mohammadi S, Jarnik M, Machner MP.

J Bacteriol. 2012 Mar;194(6):1389-400. doi: 10.1128/JB.06306-11. Epub 2012 Jan 6.

20.

High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA.

Schoebel S, Blankenfeldt W, Goody RS, Itzen A.

EMBO Rep. 2010 Aug;11(8):598-604. doi: 10.1038/embor.2010.97. Epub 2010 Jul 9.

Supplemental Content

Support Center