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Items: 1 to 20 of 99

1.

A novel monoclonal antibody to CD40 prolongs islet allograft survival.

Lowe M, Badell IR, Thompson P, Martin B, Leopardi F, Strobert E, Price AA, Abdulkerim HS, Wang R, Iwakoshi NN, Adams AB, Kirk AD, Larsen CP, Reimann KA.

Am J Transplant. 2012 Aug;12(8):2079-87. doi: 10.1111/j.1600-6143.2012.04054.x. Epub 2012 May 8.

2.

CTLA4Ig prevents alloantibody formation following nonhuman primate islet transplantation using the CD40-specific antibody 3A8.

Badell IR, Russell MC, Cardona K, Shaffer VO, Turner AP, Avila JG, Cano JA, Leopardi FV, Song M, Strobert EA, Ford ML, Pearson TC, Kirk AD, Larsen CP.

Am J Transplant. 2012 Jul;12(7):1918-23. doi: 10.1111/j.1600-6143.2012.04029.x. Epub 2012 Mar 28.

3.

CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates.

Thompson P, Cardona K, Russell M, Badell IR, Shaffer V, Korbutt G, Rayat GR, Cano J, Song M, Jiang W, Strobert E, Rajotte R, Pearson T, Kirk AD, Larsen CP.

Am J Transplant. 2011 May;11(5):947-57. doi: 10.1111/j.1600-6143.2011.03509.x.

4.

Nondepleting anti-CD40-based therapy prolongs allograft survival in nonhuman primates.

Badell IR, Thompson PW, Turner AP, Russell MC, Avila JG, Cano JA, Robertson JM, Leopardi FV, Strobert EA, Iwakoshi NN, Reimann KA, Ford ML, Kirk AD, Larsen CP.

Am J Transplant. 2012 Jan;12(1):126-35. doi: 10.1111/j.1600-6143.2011.03736.x. Epub 2011 Sep 15.

5.

A novel, blocking, Fc-silent anti-CD40 monoclonal antibody prolongs nonhuman primate renal allograft survival in the absence of B cell depletion.

Cordoba F, Wieczorek G, Audet M, Roth L, Schneider MA, Kunkler A, Stuber N, Erard M, Ceci M, Baumgartner R, Apolloni R, Cattini A, Robert G, Ristig D, Munz J, Haeberli L, Grau R, Sickert D, Heusser C, Espie P, Bruns C, Patel D, Rush JS.

Am J Transplant. 2015 Nov;15(11):2825-36. doi: 10.1111/ajt.13377. Epub 2015 Jul 2.

6.

Prolonged islet graft survival in NOD mice by blockade of the CD40-CD154 pathway of T-cell costimulation.

Molano RD, Berney T, Li H, Cattan P, Pileggi A, Vizzardelli C, Kenyon NS, Ricordi C, Burkly LC, Inverardi L.

Diabetes. 2001 Feb;50(2):270-6.

7.

Alternative immunomodulatory strategies for xenotransplantation: CD40/154 pathway-sparing regimens promote xenograft survival.

Thompson P, Badell IR, Lowe M, Turner A, Cano J, Avila J, Azimzadeh A, Cheng X, Pierson RN 3rd, Johnson B, Robertson J, Song M, Leopardi F, Strobert E, Korbutt G, Rayat G, Rajotte R, Larsen CP, Kirk AD.

Am J Transplant. 2012 Jul;12(7):1765-75. doi: 10.1111/j.1600-6143.2012.04031.x. Epub 2012 Mar 28.

8.

Anti-CD40 therapy extends renal allograft survival in rhesus macaques.

Pearson TC, Trambley J, Odom K, Anderson DC, Cowan S, Bray R, Lin A, Hollenbaugh D, Aruffo A, Siadak AW, Strobert E, Hennigar R, Larsen CP.

Transplantation. 2002 Oct 15;74(7):933-40.

PMID:
12394833
9.

Costimulatory blockade of CD154-CD40 in combination with T-cell lymphodepletion results in prevention of allogeneic sensitization.

Xu H, Yan J, Huang Y, Chilton PM, Ding C, Schanie CL, Wang L, Ildstad ST.

Blood. 2008 Mar 15;111(6):3266-75. Epub 2007 Sep 7.

10.

Dissociation between anti-porcine albumin and anti-Gal antibody responses in non-human primate recipients of intraportal porcine islet transplantation.

Kang HJ, Lee H, Park EM, Kim JM, Shin JS, Kim JS, Park CG, Park SH, Kim SJ.

Xenotransplantation. 2015 Mar-Apr;22(2):124-34. doi: 10.1111/xen.12152. Epub 2015 Jan 30. Erratum in: Xenotransplantation. 2016 May;23(3):251.

PMID:
25641336
11.

The complement dependent cytotoxicity (CDC) immune effector mechanism contributes to anti-CD154 induced immunosuppression.

Sánchez-Fueyo A, Domenig C, Strom TB, Zheng XX.

Transplantation. 2002 Sep 27;74(6):898-900.

12.

Long-term hepatic allograft acceptance based on CD40 blockade by ASKP1240 in nonhuman primates.

Oura T, Yamashita K, Suzuki T, Fukumori D, Watanabe M, Hirokata G, Wakayama K, Taniguchi M, Shimamura T, Miura T, Okimura K, Maeta K, Haga H, Kubota K, Shimizu A, Sakai F, Furukawa H, Todo S.

Am J Transplant. 2012 Jul;12(7):1740-54. doi: 10.1111/j.1600-6143.2012.04014.x. Epub 2012 Mar 15.

13.

Blockade of CD40-mediated signaling is sufficient for inducing islet but not skin transplantation tolerance.

Phillips NE, Markees TG, Mordes JP, Greiner DL, Rossini AA.

J Immunol. 2003 Mar 15;170(6):3015-23.

14.

Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival.

Adams AB, Shirasugi N, Jones TR, Durham MM, Strobert EA, Cowan S, Rees P, Hendrix R, Price K, Kenyon NS, Hagerty D, Townsend R, Hollenbaugh D, Pearson TC, Larsen CP.

J Immunol. 2005 Jan 1;174(1):542-50.

16.

ASKP1240, a fully human anti-CD40 monoclonal antibody, prolongs pancreatic islet allograft survival in nonhuman primates.

Watanabe M, Yamashita K, Suzuki T, Kamachi H, Kuraya D, Koshizuka Y, Ogura M, Yoshida T, Aoyagi T, Fukumori D, Shimamura T, Okimura K, Maeta K, Miura T, Sakai F, Todo S.

Am J Transplant. 2013 Aug;13(8):1976-88. doi: 10.1111/ajt.12330. Epub 2013 Jul 10.

17.

CD40 blockade combines with CTLA4Ig and sirolimus to produce mixed chimerism in an MHC-defined rhesus macaque transplant model.

Page A, Srinivasan S, Singh K, Russell M, Hamby K, Deane T, Sen S, Stempora L, Leopardi F, Price AA, Strobert E, Reimann KA, Kirk AD, Larsen CP, Kean LS.

Am J Transplant. 2012 Jan;12(1):115-25. doi: 10.1111/j.1600-6143.2011.03737.x. Epub 2011 Sep 19.

18.

Blockade of CD40-CD154 at the time of donor-specific blood transfusion does not lead to prolonged kidney allograft survival in nonhuman primates.

Ringers J, Haanstra KG, Kroczek RA, Kliem K, Kuhn EM, Wubben J, Ossevoort MA, Volk HD, Jonker M.

Transplantation. 2002 Mar 27;73(6):862-6.

PMID:
11923684
19.

Anti-mouse CD154 antibody treatment facilitates generation of mixed xenogeneic rat hematopoietic chimerism, prevents wasting disease and prolongs xenograft survival in mice.

Masaki H, Appel MC, Leahy L, Leif J, Paquin L, Shultz LD, Mordes JP, Greiner DL, Rossini AA.

Xenotransplantation. 2006 May;13(3):224-32.

PMID:
16756565
20.

The effect of simultaneous CD154 and LFA-1 blockade on the survival of allogeneic islet grafts in nonobese diabetic mice.

Berney T, Pileggi A, Molano RD, Poggioli R, Zahr E, Ricordi C, Inverardi L.

Transplantation. 2003 Dec 27;76(12):1669-74.

PMID:
14688513

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