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Obesity and asthma: an inflammatory disease of adipose tissue not the airway.

Sideleva O, Suratt BT, Black KE, Tharp WG, Pratley RE, Forgione P, Dienz O, Irvin CG, Dixon AE.

Am J Respir Crit Care Med. 2012 Oct 1;186(7):598-605. doi: 10.1164/rccm.201203-0573OC. Epub 2012 Jul 26.


Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype.

Lugogo NL, Hollingsworth JW, Howell DL, Que LG, Francisco D, Church TD, Potts-Kant EN, Ingram JL, Wang Y, Jung SH, Kraft M.

Am J Respir Crit Care Med. 2012 Sep 1;186(5):404-11. doi: 10.1164/rccm.201109-1671OC. Epub 2012 Jul 5. Retraction in: Am J Respir Crit Care Med. 2015 Jul 15;192(2):264.


Airway and plasma leptin and adiponectin in lean and obese asthmatics and controls.

Holguin F, Rojas M, Brown LA, Fitzpatrick AM.

J Asthma. 2011 Apr;48(3):217-23. doi: 10.3109/02770903.2011.555033. Epub 2011 Feb 21.


The Roles of Adipokines, Proinflammatory Cytokines, and Adipose Tissue Macrophages in Obesity-Associated Insulin Resistance in Modest Obesity and Early Metabolic Dysfunction.

Kang YE, Kim JM, Joung KH, Lee JH, You BR, Choi MJ, Ryu MJ, Ko YB, Lee MA, Lee J, Ku BJ, Shong M, Lee KH, Kim HJ.

PLoS One. 2016 Apr 21;11(4):e0154003. doi: 10.1371/journal.pone.0154003. eCollection 2016 Apr 21.


Obesity, airway hyperresponsiveness, and inflammation.

Shore SA.

J Appl Physiol (1985). 2010 Mar;108(3):735-43. doi: 10.1152/japplphysiol.00749.2009. Epub 2009 Oct 29. Review.


Effect of bariatric surgery on asthma control, lung function and bronchial and systemic inflammation in morbidly obese subjects with asthma.

van Huisstede A, Rudolphus A, Castro Cabezas M, Biter LU, van de Geijn GJ, Taube C, Hiemstra PS, Braunstahl GJ.

Thorax. 2015 Jul;70(7):659-67. doi: 10.1136/thoraxjnl-2014-206712. Epub 2015 Apr 30.


[Bronchial asthma in obesity--a distinct phenotype of asthma?].

Ziora D, Sitek P, Machura E, Ziora K.

Pneumonol Alergol Pol. 2012;80(5):454-62. Review. Polish.


Obesity, adipokines, and lung disease.

Sood A.

J Appl Physiol (1985). 2010 Mar;108(3):744-53. doi: 10.1152/japplphysiol.00838.2009. Epub 2009 Nov 19. Review.


Effects of bariatric surgery on human small artery function: evidence for reduction in perivascular adipocyte inflammation, and the restoration of normal anticontractile activity despite persistent obesity.

Aghamohammadzadeh R, Greenstein AS, Yadav R, Jeziorska M, Hama S, Soltani F, Pemberton PW, Ammori B, Malik RA, Soran H, Heagerty AM.

J Am Coll Cardiol. 2013 Jul 9;62(2):128-35. doi: 10.1016/j.jacc.2013.04.027. Epub 2013 May 9.


Adipose inflammation in obesity: relationship with circulating levels of inflammatory markers and association with surgery-induced weight loss.

Lasselin J, Magne E, Beau C, Ledaguenel P, Dexpert S, Aubert A, Layé S, Capuron L.

J Clin Endocrinol Metab. 2014 Jan;99(1):E53-61. doi: 10.1210/jc.2013-2673. Epub 2013 Dec 20.


Associations of visceral and abdominal subcutaneous adipose tissue with markers of cardiac and metabolic risk in obese adults.

Neeland IJ, Ayers CR, Rohatgi AK, Turer AT, Berry JD, Das SR, Vega GL, Khera A, McGuire DK, Grundy SM, de Lemos JA.

Obesity (Silver Spring). 2013 Sep;21(9):E439-47. doi: 10.1002/oby.20135. Epub 2013 May 19.


Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation.

Dixon AE, Pratley RE, Forgione PM, Kaminsky DA, Whittaker-Leclair LA, Griffes LA, Garudathri J, Raymond D, Poynter ME, Bunn JY, Irvin CG.

J Allergy Clin Immunol. 2011 Sep;128(3):508-15.e1-2. doi: 10.1016/j.jaci.2011.06.009. Epub 2011 Jul 23.


Modulation of adipose tissue inflammation by FOXP3+ Treg cells, IL-10, and TGF-β in metabolically healthy class III obese individuals.

Pereira S, Teixeira L, Aguilar E, Oliveira M, Savassi-Rocha A, Pelaez JN, Capettini L, Diniz MT, Ferreira A, Alvarez-Leite J.

Nutrition. 2014 Jul-Aug;30(7-8):784-90. doi: 10.1016/j.nut.2013.11.023. Epub 2013 Dec 8.


Cluster analysis of obesity and asthma phenotypes.

Sutherland ER, Goleva E, King TS, Lehman E, Stevens AD, Jackson LP, Stream AR, Fahy JV, Leung DY; Asthma Clinical Research Network..

PLoS One. 2012;7(5):e36631. doi: 10.1371/journal.pone.0036631. Epub 2012 May 11.


Inflammation correlates with markers of T-cell subsets including regulatory T cells in adipose tissue from obese patients.

Zeyda M, Huber J, Prager G, Stulnig TM.

Obesity (Silver Spring). 2011 Apr;19(4):743-8. doi: 10.1038/oby.2010.123. Epub 2010 May 27.


Changes in metabolic profile and adipoinsular axis in morbidly obese premenopausal females treated with restrictive bariatric surgery.

Marantos G, Daskalakis M, Karkavitsas N, Matalliotakis I, Papadakis JA, Melissas J.

World J Surg. 2011 Sep;35(9):2022-30. doi: 10.1007/s00268-011-1165-9.


Regulation of the fibrosis and angiogenesis promoter SPARC/osteonectin in human adipose tissue by weight change, leptin, insulin, and glucose.

Kos K, Wong S, Tan B, Gummesson A, Jernas M, Franck N, Kerrigan D, Nystrom FH, Carlsson LM, Randeva HS, Pinkney JH, Wilding JP.

Diabetes. 2009 Aug;58(8):1780-8. doi: 10.2337/db09-0211. Epub 2009 Jun 9.


Low-grade adipose tissue inflammation in patients with mild-to-moderate chronic obstructive pulmonary disease.

van den Borst B, Gosker HR, Wesseling G, de Jager W, Hellwig VA, Snepvangers FJ, Schols AM.

Am J Clin Nutr. 2011 Dec;94(6):1504-12. doi: 10.3945/ajcn.111.023911. Epub 2011 Nov 9.


Diet-induced obesity alters immune cell infiltration and expression of inflammatory cytokine genes in mouse ovarian and peri-ovarian adipose depot tissues.

Nteeba J, Ortinau LC, Perfield JW 2nd, Keating AF.

Mol Reprod Dev. 2013 Nov;80(11):948-58. doi: 10.1002/mrd.22231. Epub 2013 Sep 16.


Lipomatosis-associated inflammation and excess collagen may contribute to lower relative resting energy expenditure in women with adiposis dolorosa.

Herbst KL, Coviello AD, Chang A, Boyle DL.

Int J Obes (Lond). 2009 Sep;33(9):1031-8. doi: 10.1038/ijo.2009.119. Epub 2009 Jul 21.

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