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Items: 1 to 20 of 196

1.

Epstein-Barr virus latent membrane protein-2A induces ITAM/Syk- and Akt-dependent epithelial migration through αv-integrin membrane translocation.

Fotheringham JA, Coalson NE, Raab-Traub N.

J Virol. 2012 Oct;86(19):10308-20. doi: 10.1128/JVI.00853-12. Epub 2012 Jul 25.

2.

Syk tyrosine kinase mediates Epstein-Barr virus latent membrane protein 2A-induced cell migration in epithelial cells.

Lu J, Lin WH, Chen SY, Longnecker R, Tsai SC, Chen CL, Tsai CH.

J Biol Chem. 2006 Mar 31;281(13):8806-14. Epub 2006 Jan 23.

4.

Epstein-Barr virus latent membrane protein 2A activates beta-catenin signaling in epithelial cells.

Morrison JA, Klingelhutz AJ, Raab-Traub N.

J Virol. 2003 Nov;77(22):12276-84.

6.

The Shb signalling scaffold binds to and regulates constitutive signals from the Epstein-Barr virus LMP2A membrane protein.

Matskova LV, Helmstetter C, Ingham RJ, Gish G, Lindholm CK, Ernberg I, Pawson T, Winberg G.

Oncogene. 2007 Jul 26;26(34):4908-17. Epub 2007 Feb 19.

PMID:
17311000
7.

SYK interaction with ITGβ4 suppressed by Epstein-Barr virus LMP2A modulates migration and invasion of nasopharyngeal carcinoma cells.

Zhou X, Matskova L, Rathje LS, Xiao X, Gish G, Werner M, Ignatyev I, Yu N, Zhao W, Tian F, Hou B, Zhang Z, Pawson T, Chen F, Ernberg I.

Oncogene. 2015 Aug 20;34(34):4491-9. doi: 10.1038/onc.2014.380. Epub 2014 Dec 22.

PMID:
25531330
8.

Src kinase and Syk activation initiate PI3K signaling by a chimeric latent membrane protein 1 in Epstein-Barr virus (EBV)+ B cell lymphomas.

Hatton O, Lambert SL, Krams SM, Martinez OM.

PLoS One. 2012;7(8):e42610. doi: 10.1371/journal.pone.0042610. Epub 2012 Aug 3.

9.

The LMP2A protein of Epstein-Barr virus regulates phosphorylation of ITSN1 and Shb adaptors by tyrosine kinases.

Dergai O, Dergai M, Skrypkina I, Matskova L, Tsyba L, Gudkova D, Rynditch A.

Cell Signal. 2013 Jan;25(1):33-40. doi: 10.1016/j.cellsig.2012.09.011. Epub 2012 Sep 10.

PMID:
22975684
10.

Epstein-Barr virus latent membrane protein 2 effects on epithelial acinus development reveal distinct requirements for the PY and YEEA motifs.

Fotheringham JA, Raab-Traub N.

J Virol. 2013 Dec;87(24):13803-15. doi: 10.1128/JVI.02203-13. Epub 2013 Oct 9.

11.

The Epstein-Barr virus causes epithelial-mesenchymal transition in human corneal epithelial cells via Syk/src and Akt/Erk signaling pathways.

Park GB, Kim D, Kim YS, Kim S, Lee HK, Yang JW, Hur DY.

Invest Ophthalmol Vis Sci. 2014 Mar 20;55(3):1770-9. doi: 10.1167/iovs.13-12988.

PMID:
24569586
12.

Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked inhibitor of apoptosis protein (XIAP) to promote survival of Epstein-Barr virus+ (EBV+) B cell lymphomas.

Hatton O, Phillips LK, Vaysberg M, Hurwich J, Krams SM, Martinez OM.

J Biol Chem. 2011 Oct 28;286(43):37368-78. doi: 10.1074/jbc.M111.255125. Epub 2011 Sep 9.

13.

Epstein-Barr virus latent membrane protein 2A promotes invasion of nasopharyngeal carcinoma cells through ERK/Fra-1-mediated induction of matrix metalloproteinase 9.

Lan YY, Hsiao JR, Chang KC, Chang JS, Chen CW, Lai HC, Wu SY, Yeh TH, Chang FH, Lin WH, Su IJ, Chang Y.

J Virol. 2012 Jun;86(12):6656-67. doi: 10.1128/JVI.00174-12. Epub 2012 Apr 18.

14.

Latent membrane protein 2A-mediated effects on the phosphatidylinositol 3-Kinase/Akt pathway.

Swart R, Ruf IK, Sample J, Longnecker R.

J Virol. 2000 Nov;74(22):10838-45.

15.

Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module.

Engels N, Merchant M, Pappu R, Chan AC, Longnecker R, Wienands J.

J Exp Med. 2001 Aug 6;194(3):255-64.

16.
17.

The c-Cbl proto-oncoprotein downregulates EBV LMP2A signaling.

Ikeda M, Longnecker R.

Virology. 2009 Mar 1;385(1):183-91. doi: 10.1016/j.virol.2008.11.018. Epub 2008 Dec 10.

20.

The Epstein-Barr virus protein, latent membrane protein 2A, co-opts tyrosine kinases used by the T cell receptor.

Ingham RJ, Raaijmakers J, Lim CS, Mbamalu G, Gish G, Chen F, Matskova L, Ernberg I, Winberg G, Pawson T.

J Biol Chem. 2005 Oct 7;280(40):34133-42. Epub 2005 Aug 8.

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