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Items: 1 to 20 of 51

1.

The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells.

Wei C, Bhattaram VK, Igwe JC, Fleming E, Tirnauer JS.

PLoS One. 2012;7(7):e41118. doi: 10.1371/journal.pone.0041118. Epub 2012 Jul 18.

2.

AMPK regulates mitotic spindle orientation through phosphorylation of myosin regulatory light chain.

Thaiparambil JT, Eggers CM, Marcus AI.

Mol Cell Biol. 2012 Aug;32(16):3203-17. doi: 10.1128/MCB.00418-12. Epub 2012 Jun 11.

3.

Mitotic spindle misorientation in cancer--out of alignment and into the fire.

Pease JC, Tirnauer JS.

J Cell Sci. 2011 Apr 1;124(Pt 7):1007-16. doi: 10.1242/jcs.081406.

4.

Cadherin adhesion receptors orient the mitotic spindle during symmetric cell division in mammalian epithelia.

den Elzen N, Buttery CV, Maddugoda MP, Ren G, Yap AS.

Mol Biol Cell. 2009 Aug;20(16):3740-50. doi: 10.1091/mbc.E09-01-0023. Epub 2009 Jun 24.

5.

LKB1-AMPK modulates nutrient-induced changes in the mode of division of intestinal epithelial crypt cells in mice.

Blackmore K, Zhou W, Dailey MJ.

Exp Biol Med (Maywood). 2017 Sep;242(15):1490-1498. doi: 10.1177/1535370217724427. Epub 2017 Aug 2.

PMID:
28766983
6.

SIRT1 promotes proliferation and prevents senescence through targeting LKB1 in primary porcine aortic endothelial cells.

Zu Y, Liu L, Lee MY, Xu C, Liang Y, Man RY, Vanhoutte PM, Wang Y.

Circ Res. 2010 Apr 30;106(8):1384-93. doi: 10.1161/CIRCRESAHA.109.215483. Epub 2010 Mar 4.

7.

The serine/threonine kinase LKB1 controls thymocyte survival through regulation of AMPK activation and Bcl-XL expression.

Cao Y, Li H, Liu H, Zheng C, Ji H, Liu X.

Cell Res. 2010 Jan;20(1):99-108. doi: 10.1038/cr.2009.141. Epub 2009 Dec 22.

PMID:
20029389
8.

Spindle misorientation in tumors from APC(min/+) mice.

Fleming ES, Temchin M, Wu Q, Maggio-Price L, Tirnauer JS.

Mol Carcinog. 2009 Jul;48(7):592-8. doi: 10.1002/mc.20506.

PMID:
19123231
9.

C-terminal phosphorylation of LKB1 is not required for regulation of AMP-activated protein kinase, BRSK1, BRSK2, or cell cycle arrest.

Fogarty S, Hardie DG.

J Biol Chem. 2009 Jan 2;284(1):77-84. doi: 10.1074/jbc.M806152200. Epub 2008 Oct 14.

10.

Regulation of epithelial tight junction assembly and disassembly by AMP-activated protein kinase.

Zheng B, Cantley LC.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):819-22. Epub 2007 Jan 4.

11.

The LKB1/AMPK polarity pathway.

Mirouse V, Billaud M.

FEBS Lett. 2011 Apr 6;585(7):981-5. doi: 10.1016/j.febslet.2010.12.025. Epub 2010 Dec 23. Review.

12.

Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.

Forcet C, Etienne-Manneville S, Gaude H, Fournier L, Debilly S, Salmi M, Baas A, Olschwang S, Clevers H, Billaud M.

Hum Mol Genet. 2005 May 15;14(10):1283-92. Epub 2005 Mar 30.

PMID:
15800014
13.

Hyaluronan-CD44 pathway regulates orientation of mitotic spindle in normal epithelial cells.

Fujiwara T, Kawakatsu T, Tayama S, Kobayashi Y, Sugiura N, Kimata K, Takai Y.

Genes Cells. 2008 Jul;13(7):759-70. doi: 10.1111/j.1365-2443.2008.01203.x. Epub 2008 May 30.

14.

Drosophila aPKC is required for mitotic spindle orientation during symmetric division of epithelial cells.

Guilgur LG, PrudĂȘncio P, Ferreira T, Pimenta-Marques AR, Martinho RG.

Development. 2012 Feb;139(3):503-13. doi: 10.1242/dev.071027.

15.

SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation.

Lan F, Cacicedo JM, Ruderman N, Ido Y.

J Biol Chem. 2008 Oct 10;283(41):27628-35. doi: 10.1074/jbc.M805711200. Epub 2008 Aug 7.

16.

Regulation of Rac1 by simvastatin in endothelial cells: differential roles of AMP-activated protein kinase and calmodulin-dependent kinase kinase-beta.

Kou R, Sartoretto J, Michel T.

J Biol Chem. 2009 May 29;284(22):14734-43. doi: 10.1074/jbc.M808664200. Epub 2009 Mar 30.

17.

Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring.

Beamish H, de Boer L, Giles N, Stevens F, Oakes V, Gabrielli B.

J Biol Chem. 2009 Oct 16;284(42):29015-23. doi: 10.1074/jbc.M109.042820. Epub 2009 Aug 24.

18.

RHAMM promotes interphase microtubule instability and mitotic spindle integrity through MEK1/ERK1/2 activity.

Tolg C, Hamilton SR, Morningstar L, Zhang J, Zhang S, Esguerra KV, Telmer PG, Luyt LG, Harrison R, McCarthy JB, Turley EA.

J Biol Chem. 2010 Aug 20;285(34):26461-74. doi: 10.1074/jbc.M110.121491. Epub 2010 Jun 17.

19.

Function of Drg1/Rit42 in p53-dependent mitotic spindle checkpoint.

Kim KT, Ongusaha PP, Hong YK, Kurdistani SK, Nakamura M, Lu KP, Lee SW.

J Biol Chem. 2004 Sep 10;279(37):38597-602. Epub 2004 Jul 9.

20.

AMP-activated protein kinase regulates the assembly of epithelial tight junctions.

Zhang L, Li J, Young LH, Caplan MJ.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17272-7. Epub 2006 Nov 6.

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