Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 106

1.

A novel flow cytometric HTS assay reveals functional modulators of ATP binding cassette transporter ABCB6.

Polireddy K, Khan MM, Chavan H, Young S, Ma X, Waller A, Garcia M, Perez D, Chavez S, Strouse JJ, Haynes MK, Bologa CG, Oprea TI, Tegos GP, Sklar LA, Krishnamurthy P.

PLoS One. 2012;7(7):e40005. doi: 10.1371/journal.pone.0040005. Epub 2012 Jul 10.

2.

Identification of a mammalian mitochondrial porphyrin transporter.

Krishnamurthy PC, Du G, Fukuda Y, Sun D, Sampath J, Mercer KE, Wang J, Sosa-Pineda B, Murti KG, Schuetz JD.

Nature. 2006 Oct 5;443(7111):586-9. Epub 2006 Sep 27.

PMID:
17006453
3.

ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity.

Ulrich DL, Lynch J, Wang Y, Fukuda Y, Nachagari D, Du G, Sun D, Fan Y, Tsurkan L, Potter PM, Rehg JE, Schuetz JD.

J Biol Chem. 2012 Apr 13;287(16):12679-90. doi: 10.1074/jbc.M111.336180. Epub 2012 Jan 31.

4.
5.

Cell survival under stress is enhanced by a mitochondrial ATP-binding cassette transporter that regulates hemoproteins.

Lynch J, Fukuda Y, Krishnamurthy P, Du G, Schuetz JD.

Cancer Res. 2009 Jul 1;69(13):5560-7. doi: 10.1158/0008-5472.CAN-09-0078. Epub 2009 Jun 23.

6.

Efficient purification and reconstitution of ATP binding cassette transporter B6 (ABCB6) for functional and structural studies.

Chavan H, Khan MM, Tegos G, Krishnamurthy P.

J Biol Chem. 2013 Aug 2;288(31):22658-69. doi: 10.1074/jbc.M113.485284. Epub 2013 Jun 21.

7.

Human ABCB6 localizes to both the outer mitochondrial membrane and the plasma membrane.

Paterson JK, Shukla S, Black CM, Tachiwada T, Garfield S, Wincovitch S, Ernst DN, Agadir A, Li X, Ambudkar SV, Szakacs G, Akiyama S, Gottesman MM.

Biochemistry. 2007 Aug 21;46(33):9443-52. Epub 2007 Jul 28.

PMID:
17661442
8.

Increased expression of ABCB6 enhances protoporphyrin IX accumulation and photodynamic effect in human glioma.

Zhao SG, Chen XF, Wang LG, Yang G, Han DY, Teng L, Yang MC, Wang DY, Shi C, Liu YH, Zheng BJ, Shi CB, Gao X, Rainov NG.

Ann Surg Oncol. 2013 Dec;20(13):4379-88. doi: 10.1245/s10434-011-2201-6. Epub 2012 Jun 12.

PMID:
22688660
9.

Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes.

Kiss K, Brozik A, Kucsma N, Toth A, Gera M, Berry L, Vallentin A, Vial H, Vidal M, Szakacs G.

PLoS One. 2012;7(5):e37378. doi: 10.1371/journal.pone.0037378. Epub 2012 May 24.

10.

High-throughput flow cytometry to detect selective inhibitors of ABCB1, ABCC1, and ABCG2 transporters.

Ivnitski-Steele I, Larson RS, Lovato DM, Khawaja HM, Winter SS, Oprea TI, Sklar LA, Edwards BS.

Assay Drug Dev Technol. 2008 Apr;6(2):263-76. doi: 10.1089/adt.2007.107.

PMID:
18205550
11.

Functional significance of the ATP-binding cassette transporter B6 in hepatocellular carcinoma.

Polireddy K, Chavan H, Abdulkarim BA, Krishnamurthy P.

Mol Oncol. 2011 Oct;5(5):410-25. doi: 10.1016/j.molonc.2011.07.005. Epub 2011 Jul 28.

12.

The role of ABCG2 and ABCB6 in porphyrin metabolism and cell survival.

Krishnamurthy P, Schuetz JD.

Curr Pharm Biotechnol. 2011 Apr;12(4):647-55. Review.

PMID:
21118089
13.

A high throughput flow cytometric assay platform targeting transporter inhibition.

Tegos GP, Evangelisti AM, Strouse JJ, Ursu O, Bologa C, Sklar LA.

Drug Discov Today Technol. 2014 Jun;12:e95-103. doi: 10.1016/j.ddtec.2014.03.010. Review.

14.

The monoamine oxidase A inhibitor clorgyline is a broad-spectrum inhibitor of fungal ABC and MFS transporter efflux pump activities which reverses the azole resistance of Candida albicans and Candida glabrata clinical isolates.

Holmes AR, Keniya MV, Ivnitski-Steele I, Monk BC, Lamping E, Sklar LA, Cannon RD.

Antimicrob Agents Chemother. 2012 Mar;56(3):1508-15. doi: 10.1128/AAC.05706-11. Epub 2011 Dec 27.

15.

Human Adenine Nucleotide Translocase (ANT) Modulators Identified by High-Throughput Screening of Transgenic Yeast.

Zhang Y, Tian D, Matsuyama H, Hamazaki T, Shiratsuchi T, Terada N, Hook DJ, Walters MA, Georg GI, Hawkinson JE.

J Biomol Screen. 2016 Apr;21(4):381-90. doi: 10.1177/1087057115624637. Epub 2016 Jan 8.

PMID:
26746582
16.

Mitochondrial localization of ABC transporter ABCG2 and its function in 5-aminolevulinic acid-mediated protoporphyrin IX accumulation.

Kobuchi H, Moriya K, Ogino T, Fujita H, Inoue K, Shuin T, Yasuda T, Utsumi K, Utsumi T.

PLoS One. 2012;7(11):e50082. doi: 10.1371/journal.pone.0050082. Epub 2012 Nov 26.

17.

A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry.

Strouse JJ, Ivnitski-Steele I, Khawaja HM, Perez D, Ricci J, Yao T, Weiner WS, Schroeder CE, Simpson DS, Maki BE, Li K, Golden JE, Foutz TD, Waller A, Evangelisti AM, Young SM, Chavez SE, Garcia MJ, Ursu O, Bologa CG, Carter MB, Salas VM, Gouveia K, Tegos GP, Oprea TI, Edwards BS, Aubé J, Larson RS, Sklar LA.

J Biomol Screen. 2013 Jan;18(1):26-38. doi: 10.1177/1087057112456875. Epub 2012 Aug 24.

18.

Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8.

Fukuda Y, Aguilar-Bryan L, Vaxillaire M, Dechaume A, Wang Y, Dean M, Moitra K, Bryan J, Schuetz JD.

J Biol Chem. 2011 Mar 11;286(10):8481-92. doi: 10.1074/jbc.M110.174516. Epub 2011 Jan 3.

19.

A High-Throughput Flow Cytometry Assay for Identification of Inhibitors of 3',5'-Cyclic Adenosine Monophosphate Efflux.

Perez D, Simons PC, Smagley Y, Sklar LA, Chigaev A.

Methods Mol Biol. 2016;1439:227-44. doi: 10.1007/978-1-4939-3673-1_15.

PMID:
27316999
20.

A high-throughput cell-based assay for inhibitors of ABCG2 activity.

Henrich CJ, Bokesch HR, Dean M, Bates SE, Robey RW, Goncharova EI, Wilson JA, McMahon JB.

J Biomol Screen. 2006 Mar;11(2):176-83. Epub 2006 Feb 20.

PMID:
16490770

Supplemental Content

Support Center