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1.

Psychosis Incident Cohort Outcome Study (PICOS). A multisite study of clinical, social and biological characteristics, patterns of care and predictors of outcome in first-episode psychosis. Background, methodology and overview of the patient sample.

Lasalvia A, Tosato S, Brambilla P, Bertani M, Bonetto C, Cristofalo D, Bissoli S, De Santi K, Lazzarotto L, Zanatta G, Marrella G, Mazzoncini R, Zanoni M, Garzotto N, Dolce C, Nicolau S, Ramon L, Perlini C, Rambaldelli G, Bellani M, Tansella M, Ruggeri M; PICOS-Veneto Group.

Epidemiol Psychiatr Sci. 2012 Sep;21(3):281-303. doi: 10.1017/S2045796012000315. Epub 2012 Jun 15.

PMID:
22794251
2.

The impact of cannabis use on age of onset and clinical characteristics in first-episode psychotic patients. Data from the Psychosis Incident Cohort Outcome Study (PICOS).

Tosato S, Lasalvia A, Bonetto C, Mazzoncini R, Cristofalo D, De Santi K, Bertani M, Bissoli S, Lazzarotto L, Marrella G, Lamonaca D, Riolo R, Gardellin F, Urbani A, Tansella M, Ruggeri M; PICOS-VENETO Group.

J Psychiatr Res. 2013 Apr;47(4):438-44. doi: 10.1016/j.jpsychires.2012.11.009. Epub 2013 Jan 4.

PMID:
23290558
3.

The influence of gender on clinical and social characteristics of patients at psychosis onset: A report from the Psychosis Incident Cohort Outcome Study (PICOS).

Bertani M, Lasalvia A, Bonetto C, Tosato S, Cristofalo D, Bissoli S, De Santi K, Mazzoncini R, Lazzarotto L, Santi M, Sale A, Scalabrin D, Abate M, Tansella M, Rugger M.

Psychol Med. 2012 Apr;42(4):769-80. doi: 10.1017/S0033291711001991. Erratum in: Psychol Med. 2012 Apr;42(4):781.

PMID:
21995856
4.

A multi-element psychosocial intervention for early psychosis (GET UP PIANO TRIAL) conducted in a catchment area of 10 million inhabitants: study protocol for a pragmatic cluster randomized controlled trial.

Ruggeri M, Bonetto C, Lasalvia A, De Girolamo G, Fioritti A, Rucci P, Santonastaso P, Neri G, Pileggi F, Ghigi D, Miceli M, Scarone S, Cocchi A, Torresani S, Faravelli C, Zimmermann C, Meneghelli A, Cremonese C, Scocco P, Leuci E, Mazzi F, Gennarelli M, Brambilla P, Bissoli S, Bertani ME, Tosato S, De Santi K, Poli S, Cristofalo D, Tansella M; GET UP GROUP, Ruggeri M, Mirella ME, Bissoli S, Bonetto C, Cristofalo D, De Santi K, Lasalvia A, Lunardi S, Negretto V, Poli S, Tosato S, Zamboni MG, Ballarin M, De Girolamo G, Fioritti A, Neri G, Pileggi F, Rucci P, Bocchio Chiavetto L, Scasselatti C, Zanardini R, Brambilla P, Bellani M, Bertoldo A, Marinelli V, Negretto V, Perlini C, Rambaldelli G, Lasalvia A, Bertani M, Bissoli S, Lazzarotto L, Bardella S, Gardellin F, Lamonaca D, Lasalvia A, Lunardon M, Magnabosco R, Martucci M, Nicolau S, Nifosì F, Pavanati M, Rossi M, Piazza C, Piccione G, Sala A, Sale A, Stefan B, Zotos S, Balbo M, Boggian I, Ceccato E, Dall'Agnola R, Gardellin F, Girotto B, Goss C, Lamonaca D, Lasalvia A, Leoni R, Mai A, Pasqualini A, Pavanati M, Piazza C, Piccione G, Roccato S, Rossi A, Sale A, Strizzolo S, Zotos S, Urbani A, Ald F, Bianchi B, Cappellari P, Conti R, De Battisti L, Lazzarin E, Merlin S, Migliorini G, Pozzan T, Sarto L, Visonà S, Brazzoli A, Campi A, Carmagnani R, Giambelli S, Gianella A, Lunardi L, Madaghiele D, Maestrelli P, Paiola L, Posteri E, Viola L, Zamberlan V, Zenari M, Tosato S, Zanoni M, Bonadonna G, Bonomo M, Santonastaso P, Cremonese C, Scocco P, Veronese A, Anderle P, Angelozz A, Amalric I, Baron G, Candeago EB, Castelli F, Chieco M, Cremonese C, Di Costanzo E, Derossi M, Doriguzzi M, Galvano O, Lattanz M, Lezzi R, Marcato M, Marcolin A, Marini F, Matranga M, Scalabrin D, Zucchetto M, Zadro F, Austoni G, Bianco M, Bordino F, Dario F, De Risio A, Gatto A, Granà S, Favero E, Franceschin A, Friederici S, Marangon V, Pascolo M, Ramon L, Scocco P, Veronese A, Zambolin S, Riolo R, Buffon A, Cremonese C, Di Bortolo E, Friederici S, Fortin S, Marcato M, Matarrese F, Mogni S, Codemo N, Russi A, Silvestro A, Turella E, Viel P, Dominoni A, Andreose L, Boemio M, Bressan L, Cabbia A, Canesso E, Cian R, Dal Piccol C, Dalla Pasqua MM, Di Prisco A, Mantellato L, Luison M, Morgante S, Santi M, Sacillotto M, Scabbio M, Sponga P, Sguotto ML, Stach F, Vettorato MG, Martinello G, Dassiè F, Marino S, Cibiniel L, Masetto I, Marcato M, Cabianca O, Valente A, Caberlotto L, Passoni A, Flumian P, Daniel L, Gion M, Stanziale S, Alborino F, Bortolozzo V, Bacelle L, Bicciato L, Basso D, Navaglia F, Manoni F, Ercolin M, Neri G, Giubilini F, Imbesi M, Leuci E, Mazzi F, Semrov E, Giovanni CS, Taro e Ceno V, Ovest P, Anelli S, Amore M, Bigi L, Britta W, Anna GB, Bonatti U, Borziani M, Crosato I, Galluccio R, Galeotti M, Gozzi M, Greco V, Guagnini E, Pagani S, Maccherozzi M, Marchi F, Melato E, Mazzucchi E, Marzullo F, Pellegrini P, Petrolini N, Volta P, Anelli S, Bonara F, Brusamonti E, Croci R, Flamia I, Fontana F, Losi R, Mazzi F, Marchioro R, Pagani S, Raffaini L, Ruju L, Saginario A, Tondelli MG, Marrama D, Bernardelli L, Bonacini F, Florindo A, Merli M, Nappo P, Sola L, Tondelli O, Tonna M, Torre MT, Tosatti M, Venturelli G, Zampolla D, Bernardi A, Cavalli C, Cigala L, Ciraudo C, Di Bari A, Ferri L, Gombi F, Leurini S, Mandatelli E, Maccaferri S, Oroboncoide M, Pisa B, Ricci C, Poggi E, Zurlini C, Malpeli M, Colla R, Teodori E, Vecchia L, D'Andrea R, Trenti T, Paolini P, Mazzi F, Carpeggiani P, Pileggi F, Ghigi D, Gagliostro M, Pratelli M, Rucci P, Lazzaro S, Antonelli A, Battistini L, Bellini F, Bonini E, Capelli CB, DiDomizio C, Drei C, Fucci G, Gualandi A, Grazia MR, Losi AM, Mazzoni FM, Marangoni D, Monna G, Morselli M, Oggioni A, Oprandi S, Paganelli W, Passerini M, Piscitelli M, Reggiani G, Rossi G, Salvatori F, Trasforini S, Uslenghi C, Veggetti S, Bartolucci G, Baruffa R, Bellini F, Bertelli R, Borghi L, Ciavarella P, DiDomizio C, Monna G, Oggioni A, Paltrinieri E, Rizzardi F, Serra P, Suzzi D, Carlo U, Piscitelli M, Arienti P, Aureli F, Avanzi R, Callegari V, Corsino A, Host P, Michetti R, Pratelli M, Rizzo F, Simoncelli P, Soldati E, Succi E, Bertozzi M, Canetti E, Cavicchioli L, Ceccarelli E, Cenni S, Marzola G, Gallina V, Leoni C, Olivieri A, Piccolo E, Ravagli S, Russo R, Tedeschini D, Verenini M, Abram W, Granata V, Curcio A, Guerra G, Granini S, Natali L, Montanari E, Pasi F, Ventura U, Valenti S, Francesca M, Farneti R, Ravagli P, Floris R, Maroncelli O, Volpones G, Casali D, Miceli M, Bencini A, Cellini M, De Biase L, Barbara L, Charles L, Pratesi C, Tanini A, Cellini M, Miceli M, Loparrino R, Pratesi C, Ulivelli C, Cussoto C, Dei N, Fumanti E, Pantani M, Zeloni G, Bellini R, Cellesi R, Dorigo N, Gullì P, Ialeggio L, Pisanu M, Rinaldi G, Konze A, Cocchi A, Meneghelli A, Bianco M, Modignani L, Frova M, Monzani E, Zanobio A, Malagoli M, Pagani R, Barbera S, Morganti C, Monzani E, Amadè ES, Brambilla V, Montanari A, Caterina G, Lopez C, Marocchi A, Moletta A, Sberna M, Cascio MT, Scarone S, Manzone ML, Barbara B, Mari L, Manzone ML, Razzini E, Bianchi Y, Pellizzer MR, Verdecchia A, Sferrazza MG, Manzone ML, Pismataro R, D'Eril GV, Barassi A, Pacciolla R, Faraci G, Torresani S, Rosmini B, Carpi F, Soelva M, Anderlan M, De Francesco M, Duregger E, Torresani S, Vettori C, Doimo S, Kompatscher E, Soelva M, Torresani S, Forer M, Kerschbaumer H, Gampe A, Nicoletti M, Acerbi C, Aquilino D, Azzali S, Bensi L, Bissoli S, Cappellari D, Casana E, Campagnola N, Dal Corso E, Di Micco E, Gobbi E, Ferri L, Gobbi E, Mairaghi L, Malak S, Mesiano L, Paterlini F, Perini M, Puliti EM, Rispoli R, Rizzo E, Sergenti C, Soave M, Alpi A, Bislenghi L, Bolis T, Colnaghi F, Fascendini S, Grignani S, Meneghelli A, Patelli G, Faravelli C, Casale S, Zimmermann C, Deledda G, Goss C, Mazzi M, Rimondini M, Gennarelli M, Scassellati C, Bonvicini C, Longo S, Bocchio Chiavetto L, Zanardini R, Ventriglia M, Squitti R, Frisoni G, Pievani M, Balestrieri M, Brambilla P, Perlini C, Marinelli V, Bellani M, Rambaldelli G, Bertoldo A, Atzori M, Mazzi F, Carpeggiani P, Beltramello A, Alessandrini F, Pizzini F, Zoccatelli G, Sberna M, Konze A, Politi P, Emanuele E, Brondino N, Martino G, Bergami A, Zarbo R, Riva MA, Fumagalli F, Molteni R, Calabrese F, Guidotti G, Luoni A, Macchi F, Artioli S, Baldetti M, Bizzocchi M, Bolzon D, Bonello E, Cacciari G, Carraresi C, Cascio MT, Caselli G, Furlato K, Garlassi S, Gavarini A, Lunardi S, Macchetti F, Marteddu V, Plebiscita G, Poli S, Totaro S, Bebbington P, Birchwood M, Dazzan P, Kuipers E, Thornicroft G, Pariante C, Lawrie S, Pariante C, Soares JC.

Trials. 2012 May 30;13:73.

5.

Predictors of functional and clinical outcome in early-onset first-episode psychosis: the child and adolescent first episode of psychosis (CAFEPS) study.

Parellada M, Castro-Fornieles J, Gonzalez-Pinto A, Pina-Camacho L, Moreno D, Rapado-Castro M, Otero S, de la Serna E, Moreno C, Baeza I, Graell M, Arango C.

J Clin Psychiatry. 2015 Nov;76(11):e1441-8. doi: 10.4088/JCP.13m08863.

PMID:
26580481
6.

Study protocol: The development of a pilot study employing a randomised controlled design to investigate the feasibility and effects of a peer support program following discharge from a specialist first-episode psychosis treatment centre.

Robinson J, Bruxner A, Harrigan S, Bendall S, Killackey E, Tonin V, Monson K, Thurley M, Francey S, Yung AR.

BMC Psychiatry. 2010 May 25;10:37. doi: 10.1186/1471-244X-10-37.

7.

Do the same factors predict outcome in schizophrenia and non-schizophrenia syndromes after first-episode psychosis? A two-year follow-up study.

Peña J, Segarra R, Ojeda N, García J, Eguiluz JI, Gutiérrez M.

J Psychiatr Res. 2012 Jun;46(6):774-81. doi: 10.1016/j.jpsychires.2012.03.014. Epub 2012 Apr 7.

PMID:
22487311
8.

BDNF Val66Met variants and brain volume changes in non-affective psychosis patients and healthy controls: a 3 year follow-up study.

Suárez-Pinilla P, Roiz-Santiáñez R, de la Foz VO, Mata I, Fañanas L, Brambilla P, Ruíz-Pérez E, Crespo-Facorro B.

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Aug 1;45:201-6. doi: 10.1016/j.pnpbp.2013.05.014. Epub 2013 Jun 6.

PMID:
23748016
9.

Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis.

Takahashi T, Wood SJ, Yung AR, Soulsby B, McGorry PD, Suzuki M, Kawasaki Y, Phillips LJ, Velakoulis D, Pantelis C.

Arch Gen Psychiatry. 2009 Apr;66(4):366-76. doi: 10.1001/archgenpsychiatry.2009.12.

PMID:
19349306
10.

Quality of life in patients who have remitted from their first episode of psychosis.

Cotton SM, Gleeson JF, Alvarez-Jimenez M, McGorry PD.

Schizophr Res. 2010 Aug;121(1-3):259-65. doi: 10.1016/j.schres.2010.05.027. Epub 2010 Jun 18.

PMID:
20655474
11.

Developing services for first-episode psychosis and the critical period.

Edwards J, Harris MG, Bapat S.

Br J Psychiatry Suppl. 2005 Aug;48:s91-7.

PMID:
16055816
12.

Flat affect and social functioning: a 10 year follow-up study of first episode psychosis patients.

Evensen J, Røssberg JI, Barder H, Haahr U, Hegelstad WT, Joa I, Johannessen JO, Larsen TK, Melle I, Opjordsmoen S, Rund BR, Simonsen E, Vaglum P, McGlashan T, Friis S.

Schizophr Res. 2012 Aug;139(1-3):99-104. doi: 10.1016/j.schres.2012.04.019. Epub 2012 May 23.

PMID:
22627124
13.

[Heterogeneity of the Departments of Mental Health in the Veneto Region ten years after the National Plan 1994-96 for Mental Health. Which implication for clinical practice? Findings from the PICOS Project].

Lasalvia A, Gentile B, Ruggeri M, Marcolin A, Nosè F, Cappellari L, Lamonaca D, Toniolo E, Busana C, Campedelli A, Cuccato G, Danieli A, De Nardi F, De Nardo V, Destro E, Favaretto G, Frazzingaro S, Giacopuzzi M, Pristinger P, Pullia G, Rodighiero S, Tito P, Aprile F, Nicolaou S, Coppola G, Garzotto N, Gottardi U, Lazzarin E, Migliorini G, Pavan L, Ramaciotti F, Roveroni P, Russo S, Urbani P, Tansella M; Gruppo Picos-Veneto.

Epidemiol Psichiatr Soc. 2007 Jan-Mar;16(1):59-70. Italian.

PMID:
17427605
14.

First-episode psychosis in rural, coastal and remote Australian communities.

Stain H, Sartore GM, Andrews D, Kelly B.

Australas Psychiatry. 2008 Apr;16(2):119-24. doi: 10.1080/10398560701802177.

PMID:
18335369
15.

Predictors of substance use reduction in an epidemiological first-episode psychosis cohort.

Rebgetz S, Conus P, Hides L, Kavanagh DJ, Cotton S, Schimmelmann BG, McGorry PD, Lambert M.

Early Interv Psychiatry. 2014 Nov;8(4):358-65. doi: 10.1111/eip.12067. Epub 2013 Jul 24.

PMID:
23879875
16.

Cannabis Use Is Associated With Increased Psychotic Symptoms and Poorer Psychosocial Functioning in First-Episode Psychosis: A Report From the UK National EDEN Study.

Seddon JL, Birchwood M, Copello A, Everard L, Jones PB, Fowler D, Amos T, Freemantle N, Sharma V, Marshall M, Singh SP.

Schizophr Bull. 2016 May;42(3):619-25. doi: 10.1093/schbul/sbv154. Epub 2015 Nov 4.

17.

Outcome after discharge from an early psychosis program.

Addington J, Addington D.

Schizophr Res. 2008 Dec;106(2-3):363-6. doi: 10.1016/j.schres.2008.08.032. Epub 2008 Oct 1.

PMID:
18829260
18.

Predictors of outcome three years after diagnosis of first episode psychosis.

Lucas S, Redoblado-Hodge MA, Shores A, Brennan J, Harris A.

Psychiatry Res. 2008 Oct 30;161(1):11-8. doi: 10.1016/j.psychres.2007.10.004. Epub 2008 Sep 10.

PMID:
18786728
19.

The EPPIC follow-up study of first-episode psychosis: longer-term clinical and functional outcome 7 years after index admission.

Henry LP, Amminger GP, Harris MG, Yuen HP, Harrigan SM, Prosser AL, Schwartz OS, Farrelly SE, Herrman H, Jackson HJ, McGorry PD.

J Clin Psychiatry. 2010 Jun;71(6):716-28. doi: 10.4088/JCP.08m04846yel.

PMID:
20573330
20.

Five-year outcome of first-episode psychosis before and after the implementation of a modified assertive community treatment programme.

Bodén R, Sundström J, Lindström E, Wieselgren IM, Lindström L.

Soc Psychiatry Psychiatr Epidemiol. 2010 Jun;45(6):665-74. doi: 10.1007/s00127-009-0108-3. Epub 2009 Aug 4.

PMID:
19652896

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