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Items: 1 to 20 of 126


The impact of MeCP2 loss- or gain-of-function on synaptic plasticity.

Na ES, Nelson ED, Kavalali ET, Monteggia LM.

Neuropsychopharmacology. 2013 Jan;38(1):212-9. doi: 10.1038/npp.2012.116. Epub 2012 Jul 11. Review.


Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome.

Moretti P, Levenson JM, Battaglia F, Atkinson R, Teague R, Antalffy B, Armstrong D, Arancio O, Sweatt JD, Zoghbi HY.

J Neurosci. 2006 Jan 4;26(1):319-27.


A mouse model for MeCP2 duplication syndrome: MeCP2 overexpression impairs learning and memory and synaptic transmission.

Na ES, Nelson ED, Adachi M, Autry AE, Mahgoub MA, Kavalali ET, Monteggia LM.

J Neurosci. 2012 Feb 29;32(9):3109-17. doi: 10.1523/JNEUROSCI.6000-11.2012.


Synaptic maturation at cortical projections to the lateral amygdala in a mouse model of Rett syndrome.

Gambino F, Khelfaoui M, Poulain B, Bienvenu T, Chelly J, Humeau Y.

PLoS One. 2010 Jul 2;5(7):e11399. doi: 10.1371/journal.pone.0011399.


Rett syndrome and the impact of MeCP2 associated transcriptional mechanisms on neurotransmission.

Monteggia LM, Kavalali ET.

Biol Psychiatry. 2009 Feb 1;65(3):204-10. doi: 10.1016/j.biopsych.2008.10.036. Epub 2008 Dec 5. Review.


Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome.

Asaka Y, Jugloff DG, Zhang L, Eubanks JH, Fitzsimonds RM.

Neurobiol Dis. 2006 Jan;21(1):217-27. Epub 2005 Aug 8.


The role of MeCP2 in CNS development and function.

Na ES, Monteggia LM.

Horm Behav. 2011 Mar;59(3):364-8. doi: 10.1016/j.yhbeh.2010.05.014. Epub 2010 May 31. Review.


MeCP2 expression and function during brain development: implications for Rett syndrome's pathogenesis and clinical evolution.

Kaufmann WE, Johnston MV, Blue ME.

Brain Dev. 2005 Nov;27 Suppl 1:S77-S87. Epub 2005 Sep 22. Review.


Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations.

Farra N, Zhang WB, Pasceri P, Eubanks JH, Salter MW, Ellis J.

Mol Psychiatry. 2012 Dec;17(12):1261-71. doi: 10.1038/mp.2011.180. Epub 2012 Jan 10.


GABAA receptor antagonism ameliorates behavioral and synaptic impairments associated with MeCP2 overexpression.

Na ES, Morris MJ, Nelson ED, Monteggia LM.

Neuropsychopharmacology. 2014 Jul;39(8):1946-54. doi: 10.1038/npp.2014.43. Epub 2014 Feb 19.


Metabolic fingerprints of altered brain growth, osmoregulation and neurotransmission in a Rett syndrome model.

Viola A, Saywell V, Villard L, Cozzone PJ, Lutz NW.

PLoS One. 2007 Jan 17;2(1):e157.


Early defects of GABAergic synapses in the brain stem of a MeCP2 mouse model of Rett syndrome.

Medrihan L, Tantalaki E, Aramuni G, Sargsyan V, Dudanova I, Missler M, Zhang W.

J Neurophysiol. 2008 Jan;99(1):112-21. Epub 2007 Nov 21.


Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation.

Zhou Z, Hong EJ, Cohen S, Zhao WN, Ho HY, Schmidt L, Chen WG, Lin Y, Savner E, Griffith EC, Hu L, Steen JA, Weitz CJ, Greenberg ME.

Neuron. 2006 Oct 19;52(2):255-69.


Selective impact of MeCP2 and associated histone deacetylases on the dynamics of evoked excitatory neurotransmission.

Nelson ED, Bal M, Kavalali ET, Monteggia LM.

J Neurophysiol. 2011 Jul;106(1):193-201. doi: 10.1152/jn.00751.2010. Epub 2011 Apr 20.


MeCP2 plays an analgesic role in pain transmission through regulating CREB / miR-132 pathway.

Zhang R, Huang M, Cao Z, Qi J, Qiu Z, Chiang LY.

Mol Pain. 2015 Apr 12;11:19. doi: 10.1186/s12990-015-0015-4.


MeCP2 phosphorylation is required for modulating synaptic scaling through mGluR5.

Zhong X, Li H, Chang Q.

J Neurosci. 2012 Sep 12;32(37):12841-7. doi: 10.1523/JNEUROSCI.2784-12.2012.


BDNF deregulation in Rett syndrome.

Li W, Pozzo-Miller L.

Neuropharmacology. 2014 Jan;76 Pt C:737-46. doi: 10.1016/j.neuropharm.2013.03.024. Epub 2013 Apr 15. Review.


Experimental models of Rett syndrome based on Mecp2 dysfunction.

Calfa G, Percy AK, Pozzo-Miller L.

Exp Biol Med (Maywood). 2011 Jan;236(1):3-19. doi: 10.1258/ebm.2010.010261. Review.


Adult neural function requires MeCP2.

McGraw CM, Samaco RC, Zoghbi HY.

Science. 2011 Jul 8;333(6039):186. doi: 10.1126/science.1206593. Epub 2011 Jun 2.

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