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Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis.

Pi X, Lockyer P, Dyer LA, Schisler JC, Russell B, Carey S, Sweet DT, Chen Z, Tzima E, Willis MS, Homeister JW, Moser M, Patterson C.

Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2214-22. doi: 10.1161/ATVBAHA.112.252015. Epub 2012 Jul 5.


Txnip ablation reduces vascular smooth muscle cell inflammation and ameliorates atherosclerosis in apolipoprotein E knockout mice.

Byon CH, Han T, Wu J, Hui ST.

Atherosclerosis. 2015 Aug;241(2):313-21. doi: 10.1016/j.atherosclerosis.2015.05.020. Epub 2015 Jun 3.


Human plasminogen kringle 1-5 reduces atherosclerosis and neointima formation in mice by suppressing the inflammatory signaling pathway.

Chang PC, Wu HL, Lin HC, Wang KC, Shi GY.

J Thromb Haemost. 2010 Jan;8(1):194-201. doi: 10.1111/j.1538-7836.2009.03671.x. Epub 2009 Oct 30.


BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium.

Helbing T, Rothweiler R, Ketterer E, Goetz L, Heinke J, Grundmann S, Duerschmied D, Patterson C, Bode C, Moser M.

Blood. 2011 Nov 3;118(18):5040-9. doi: 10.1182/blood-2011-03-339762. Epub 2011 Sep 7.


Role of Hic-5 in the formation of microvilli-like structures and the monocyte-endothelial interaction that accelerates atherosclerosis.

Arita-Okubo S, Kim-Kaneyama JR, Lei XF, Fu WG, Ohnishi K, Takeya M, Miyauchi A, Honda H, Itabe H, Miyazaki T, Miyazaki A.

Cardiovasc Res. 2015 Mar 1;105(3):361-71. doi: 10.1093/cvr/cvv003. Epub 2015 Jan 12. Erratum in: Cardiovasc Res. 2016 Oct;112(1):525.


Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.

Wei H, Zhang WJ, McMillen TS, Leboeuf RC, Frei B.

Atherosclerosis. 2012 Aug;223(2):306-13. doi: 10.1016/j.atherosclerosis.2012.06.013. Epub 2012 Jun 16.


LRP1-Dependent BMPER Signaling Regulates Lipopolysaccharide-Induced Vascular Inflammation.

Lockyer P, Mao H, Fan Q, Li L, Yu-Lee LY, Eissa NT, Patterson C, Xie L, Pi X.

Arterioscler Thromb Vasc Biol. 2017 Aug;37(8):1524-1535. doi: 10.1161/ATVBAHA.117.309521. Epub 2017 Jun 8.


Thioredoxin interacting protein promotes endothelial cell inflammation in response to disturbed flow by increasing leukocyte adhesion and repressing Kruppel-like factor 2.

Wang XQ, Nigro P, World C, Fujiwara K, Yan C, Berk BC.

Circ Res. 2012 Feb 17;110(4):560-8. doi: 10.1161/CIRCRESAHA.111.256362. Epub 2012 Jan 19.


Deletion of Periostin Protects Against Atherosclerosis in Mice by Altering Inflammation and Extracellular Matrix Remodeling.

Schwanekamp JA, Lorts A, Vagnozzi RJ, Vanhoutte D, Molkentin JD.

Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):60-8. doi: 10.1161/ATVBAHA.115.306397. Epub 2015 Nov 12.


IL-9 aggravates the development of atherosclerosis in ApoE-/- mice.

Zhang W, Tang T, Nie D, Wen S, Jia C, Zhu Z, Xia N, Nie S, Zhou S, Jiao J, Dong W, Lv B, Xu T, Sun B, Lu Y, Li Y, Cheng L, Liao Y, Cheng X.

Cardiovasc Res. 2015 Jun 1;106(3):453-64. doi: 10.1093/cvr/cvv110. Epub 2015 Mar 17.


Early inflammatory reactions in atherosclerosis are induced by proline-rich tyrosine kinase/reactive oxygen species-mediated release of tumor necrosis factor-alpha and subsequent activation of the p21Cip1/Ets-1/p300 system.

Katsume A, Okigaki M, Matsui A, Che J, Adachi Y, Kishita E, Yamaguchi S, Ikeda K, Ueyama T, Matoba S, Yamada H, Matsubara H.

Arterioscler Thromb Vasc Biol. 2011 May;31(5):1084-92. doi: 10.1161/ATVBAHA.110.221804. Epub 2011 Mar 3. Retraction in: Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):e6.


Potent Vasoconstrictor Kisspeptin-10 Induces Atherosclerotic Plaque Progression and Instability: Reversal by its Receptor GPR54 Antagonist.

Sato K, Shirai R, Hontani M, Shinooka R, Hasegawa A, Kichise T, Yamashita T, Yoshizawa H, Watanabe R, Matsuyama TA, Ishibashi-Ueda H, Koba S, Kobayashi Y, Hirano T, Watanabe T.

J Am Heart Assoc. 2017 Apr 14;6(4). pii: e005790. doi: 10.1161/JAHA.117.005790.


α5β1 integrin signaling mediates oxidized low-density lipoprotein-induced inflammation and early atherosclerosis.

Yurdagul A Jr, Green J, Albert P, McInnis MC, Mazar AP, Orr AW.

Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1362-73. doi: 10.1161/ATVBAHA.114.303863. Epub 2014 May 15.


EphA2 activation promotes the endothelial cell inflammatory response: a potential role in atherosclerosis.

Funk SD, Yurdagul A Jr, Albert P, Traylor JG Jr, Jin L, Chen J, Orr AW.

Arterioscler Thromb Vasc Biol. 2012 Mar;32(3):686-95. doi: 10.1161/ATVBAHA.111.242792. Epub 2012 Jan 12.


Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism.

McGraw AP, Bagley J, Chen WS, Galayda C, Nickerson H, Armani A, Caprio M, Carmeliet P, Jaffe IZ.

J Am Heart Assoc. 2013 Feb 22;2(1):e000018. doi: 10.1161/JAHA.112.000018.


BMPER is upregulated by statins and modulates endothelial inflammation by intercellular adhesion molecule-1.

Helbing T, Rothweiler R, Heinke J, Goetz L, Diehl P, Zirlik A, Patterson C, Bode C, Moser M.

Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):554-60. doi: 10.1161/ATVBAHA.109.201087. Epub 2009 Dec 30.


Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression.

Horio E, Kadomatsu T, Miyata K, Arai Y, Hosokawa K, Doi Y, Ninomiya T, Horiguchi H, Endo M, Tabata M, Tazume H, Tian Z, Takahashi O, Terada K, Takeya M, Hao H, Hirose N, Minami T, Suda T, Kiyohara Y, Ogawa H, Kaikita K, Oike Y.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):790-800. doi: 10.1161/ATVBAHA.113.303116. Epub 2014 Feb 13.


Interleukin-1 receptor type-1 in non-hematopoietic cells is the target for the pro-atherogenic effects of interleukin-1 in apoE-deficient mice.

Shemesh S, Kamari Y, Shaish A, Olteanu S, Kandel-Kfir M, Almog T, Grosskopf I, Apte RN, Harats D.

Atherosclerosis. 2012 Jun;222(2):329-36. doi: 10.1016/j.atherosclerosis.2011.12.010. Epub 2011 Dec 17.


Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling.

Gray SP, Di Marco E, Kennedy K, Chew P, Okabe J, El-Osta A, Calkin AC, Biessen EA, Touyz RM, Cooper ME, Schmidt HH, Jandeleit-Dahm KA.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):295-307. doi: 10.1161/ATVBAHA.115.307012. Epub 2015 Dec 29.


Attenuation of experimental atherosclerosis by interleukin-19.

Ellison S, Gabunia K, Kelemen SE, England RN, Scalia R, Richards JM, Orr AW, Traylor JG Jr, Rogers T, Cornwell W, Berglund LM, Goncalves I, Gomez MF, Autieri MV.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2316-24. doi: 10.1161/ATVBAHA.113.301521. Epub 2013 Aug 15. Erratum in: Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):e1. Orr, Wayne [corrected to Orr, A Wayne].

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