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Items: 1 to 20 of 726

1.

6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress.

Hu R, Zhou P, Peng YB, Xu X, Ma J, Liu Q, Zhang L, Wen XD, Qi LW, Gao N, Li P.

PLoS One. 2012;7(6):e39664. doi: 10.1371/journal.pone.0039664. Epub 2012 Jun 29.

2.

The PERK-eIF2α signaling pathway is involved in TCDD-induced ER stress in PC12 cells.

Duan Z, Zhao J, Fan X, Tang C, Liang L, Nie X, Liu J, Wu Q, Xu G.

Neurotoxicology. 2014 Sep;44:149-59. doi: 10.1016/j.neuro.2014.06.005. Epub 2014 Jun 14.

PMID:
24932542
3.
4.

Sinulariolide induced hepatocellular carcinoma apoptosis through activation of mitochondrial-related apoptotic and PERK/eIF2α/ATF4/CHOP pathway.

Chen YJ, Su JH, Tsao CY, Hung CT, Chao HH, Lin JJ, Liao MH, Yang ZY, Huang HH, Tsai FJ, Weng SH, Wu YJ.

Molecules. 2013 Aug 22;18(9):10146-61. doi: 10.3390/molecules180910146.

5.

Arsenic trioxide induces unfolded protein response in vascular endothelial cells.

Weng CY, Chiou SY, Wang L, Kou MC, Wang YJ, Wu MJ.

Arch Toxicol. 2014 Feb;88(2):213-26. doi: 10.1007/s00204-013-1101-x. Epub 2013 Jul 27.

PMID:
23892647
6.

Β-adrenergic receptor stimulation induces endoplasmic reticulum stress in adult cardiac myocytes: role in apoptosis.

Dalal S, Foster CR, Das BC, Singh M, Singh K.

Mol Cell Biochem. 2012 May;364(1-2):59-70. doi: 10.1007/s11010-011-1205-7. Epub 2012 Jan 21.

7.

6-Shogaol induces apoptosis in human leukemia cells through a process involving caspase-mediated cleavage of eIF2α.

Liu Q, Peng YB, Zhou P, Qi LW, Zhang M, Gao N, Liu EH, Li P.

Mol Cancer. 2013 Nov 12;12(1):135. doi: 10.1186/1476-4598-12-135.

8.

Anacardic acid induces cell apoptosis associated with induction of ATF4-dependent endoplasmic reticulum stress.

Huang H, Hua X, Liu N, Li X, Liu S, Chen X, Zhao C, Lan X, Yang C, Dou QP, Liu J.

Toxicol Lett. 2014 Aug 4;228(3):170-8. doi: 10.1016/j.toxlet.2014.05.012. Epub 2014 May 20.

PMID:
24853302
9.

The role of endoplasmic reticulum stress-related unfolded protein response in the radiocontrast medium-induced renal tubular cell injury.

Wu CT, Sheu ML, Tsai KS, Weng TI, Chiang CK, Liu SH.

Toxicol Sci. 2010 Apr;114(2):295-301. doi: 10.1093/toxsci/kfq006. Epub 2010 Jan 13.

PMID:
20071420
10.

6-Shogaol induces cell cycle arrest and apoptosis in human hepatoma cells through pleiotropic mechanisms.

Wu JJ, Omar HA, Lee YR, Teng YN, Chen PS, Chen YC, Huang HS, Lee KH, Hung JH.

Eur J Pharmacol. 2015 Sep 5;762:449-58. doi: 10.1016/j.ejphar.2015.06.032. Epub 2015 Jun 20.

PMID:
26101062
11.

Selective, potent blockade of the IRE1 and ATF6 pathways by 4-phenylbutyric acid analogues.

Zhang H, Nakajima S, Kato H, Gu L, Yoshitomi T, Nagai K, Shinmori H, Kokubo S, Kitamura M.

Br J Pharmacol. 2013 Oct;170(4):822-34. doi: 10.1111/bph.12306.

12.

Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis.

Cnop M, Ladriere L, Hekerman P, Ortis F, Cardozo AK, Dogusan Z, Flamez D, Boyce M, Yuan J, Eizirik DL.

J Biol Chem. 2007 Feb 9;282(6):3989-97. Epub 2006 Dec 8.

13.

Endoplasmic reticulum stress-induced resistance to doxorubicin is reversed by paeonol treatment in human hepatocellular carcinoma cells.

Fan L, Song B, Sun G, Ma T, Zhong F, Wei W.

PLoS One. 2013 May 3;8(5):e62627. doi: 10.1371/journal.pone.0062627. Print 2013.

14.

Avarol induces apoptosis in pancreatic ductal adenocarcinoma cells by activating PERK-eIF2α-CHOP signaling.

Namba T, Kodama R.

Mar Drugs. 2015 Apr 16;13(4):2376-89. doi: 10.3390/md13042376.

15.

Activation of PERK signaling attenuates Abeta-mediated ER stress.

Lee DY, Lee KS, Lee HJ, Kim DH, Noh YH, Yu K, Jung HY, Lee SH, Lee JY, Youn YC, Jeong Y, Kim DK, Lee WB, Kim SS.

PLoS One. 2010 May 5;5(5):e10489. doi: 10.1371/journal.pone.0010489.

16.

Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase.

Merlot AM, Shafie NH, Yu Y, Richardson V, Jansson PJ, Sahni S, Lane DJ, Kovacevic Z, Kalinowski DS, Richardson DR.

Biochem Pharmacol. 2016 Jun 1;109:27-47. doi: 10.1016/j.bcp.2016.04.001. Epub 2016 Apr 6.

PMID:
27059255
17.

Sorafenib enhances proteasome inhibitor-mediated cytotoxicity via inhibition of unfolded protein response and keratin phosphorylation.

Honma Y, Harada M.

Exp Cell Res. 2013 Aug 15;319(14):2166-78. doi: 10.1016/j.yexcr.2013.05.023. Epub 2013 May 31.

PMID:
23727131
18.

20(S)-Protopanaxadiol, a metabolite of ginsenosides, induced cell apoptosis through endoplasmic reticulum stress in human hepatocarcinoma HepG2 cells.

Zhu GY, Li YW, Tse AK, Hau DK, Leung CH, Yu ZL, Fong WF.

Eur J Pharmacol. 2011 Oct 1;668(1-2):88-98. doi: 10.1016/j.ejphar.2011.06.008. Epub 2011 Jun 17.

PMID:
21703260
19.

Enhancement of cisplatin cytotoxicity by SAHA involves endoplasmic reticulum stress-mediated apoptosis in oral squamous cell carcinoma cells.

Suzuki M, Endo M, Shinohara F, Echigo S, Rikiishi H.

Cancer Chemother Pharmacol. 2009 Nov;64(6):1115-22. doi: 10.1007/s00280-009-0969-x. Epub 2009 Mar 11.

PMID:
19280190
20.

Role of PERK/eIF2α/CHOP Endoplasmic Reticulum Stress Pathway in Oxidized Low-density Lipoprotein Mediated Induction of Endothelial Apoptosis.

Tao YK, Yu PL, Bai YP, Yan ST, Zhao SP, Zhang GQ.

Biomed Environ Sci. 2016 Dec;29(12):868-876. doi: 10.3967/bes2016.116.

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