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Levels of free fatty acids (FFA) are associated with insulin resistance but do not explain the relationship between adiposity and insulin resistance in Hispanic Americans: the IRAS Family Study.

Miller MR, Pereira RI, Langefeld CD, Lorenzo C, Rotter JI, Chen YD, Bergman RN, Wagenknecht LE, Norris JM, Fingerlin TE.

J Clin Endocrinol Metab. 2012 Sep;97(9):3285-91. doi: 10.1210/jc.2012-1318. Epub 2012 Jul 3.


Insulin resistance, beta cell dysfunction and visceral adiposity as predictors of incident diabetes: the Insulin Resistance Atherosclerosis Study (IRAS) Family study.

Hanley AJ, Wagenknecht LE, Norris JM, Bryer-Ash M, Chen YI, Anderson AM, Bergman R, Haffner SM.

Diabetologia. 2009 Oct;52(10):2079-86. doi: 10.1007/s00125-009-1464-y. Epub 2009 Jul 31.


Exploring differences in adiposity in two U.S. Hispanic populations of Mexican origin using social, behavioral, physiologic and genetic markers: the IRAS Family Study.

Young KA, Fingerlin TE, Langefeld CD, Lorenzo C, Haffner SM, Wagenknecht LE, Norris JM.

Ethn Dis. 2012 Winter;22(1):65-71.


Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

Wing MR, Ziegler JM, Langefeld CD, Roh BH, Palmer ND, Mayer-Davis EJ, Rewers MJ, Haffner SM, Wagenknecht LE, Bowden DW.

Int J Obes (Lond). 2011 Sep;35(9):1173-82. doi: 10.1038/ijo.2010.244. Epub 2010 Nov 23.


Genome-wide association study and follow-up analysis of adiposity traits in Hispanic Americans: the IRAS Family Study.

Norris JM, Langefeld CD, Talbert ME, Wing MR, Haritunians T, Fingerlin TE, Hanley AJ, Ziegler JT, Taylor KD, Haffner SM, Chen YD, Bowden DW, Wagenknecht LE.

Obesity (Silver Spring). 2009 Oct;17(10):1932-41. doi: 10.1038/oby.2009.143. Epub 2009 May 21.


Insulin-mediated FFA suppression is associated with triglyceridemia and insulin sensitivity independent of adiposity.

Bush NC, Basu R, Rizza RA, Nair KS, Khosla S, Jensen MD.

J Clin Endocrinol Metab. 2012 Nov;97(11):4130-8. doi: 10.1210/jc.2012-2285. Epub 2012 Aug 29.


Quantitative trait loci for abdominal fat and BMI in Hispanic-Americans and African-Americans: the IRAS Family study.

Norris JM, Langefeld CD, Scherzinger AL, Rich SS, Bookman E, Beck SR, Saad MF, Haffner SM, Bergman RN, Bowden DW, Wagenknecht LE.

Int J Obes (Lond). 2005 Jan;29(1):67-77.


Association of plasma vitamin D levels with adiposity in Hispanic and African Americans.

Young KA, Engelman CD, Langefeld CD, Hairston KG, Haffner SM, Bryer-Ash M, Norris JM.

J Clin Endocrinol Metab. 2009 Sep;94(9):3306-13. doi: 10.1210/jc.2009-0079. Epub 2009 Jun 23.


Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study.

Wing MR, Ziegler J, Langefeld CD, Ng MC, Haffner SM, Norris JM, Goodarzi MO, Bowden DW.

Hum Genet. 2009 Jun;125(5-6):615-26. doi: 10.1007/s00439-009-0656-3. Epub 2009 Mar 26.


Variant in the 3' region of the IkappaBalpha gene associated with insulin resistance in Hispanic Americans: The IRAS Family Study.

Miller MR, Zhang W, Sibbel SP, Langefeld CD, Bowden DW, Haffner SM, Bergman RN, Norris JM, Fingerlin TE.

Obesity (Silver Spring). 2010 Mar;18(3):555-62. doi: 10.1038/oby.2009.303. Epub 2009 Oct 1.


Visceral fat and prevalence of hypertension among African Americans and Hispanic Americans: findings from the IRAS family study.

Foy CG, Hsu FC, Haffner SM, Norris JM, Rotter JI, Henkin LF, Bryer-Ash M, Chen YD, Wagenknecht LE.

Am J Hypertens. 2008 Aug;21(8):910-6. doi: 10.1038/ajh.2008.213. Epub 2008 Jun 19.


Insulin sensitivity, insulin secretion, and abdominal fat: the Insulin Resistance Atherosclerosis Study (IRAS) Family Study.

Wagenknecht LE, Langefeld CD, Scherzinger AL, Norris JM, Haffner SM, Saad MF, Bergman RN.

Diabetes. 2003 Oct;52(10):2490-6.


Association between ADIPOQ SNPs with plasma adiponectin and glucose homeostasis and adiposity phenotypes in the IRAS Family Study.

An SS, Hanley AJ, Ziegler JT, Brown WM, Haffner SM, Norris JM, Rotter JI, Guo X, Chen YD, Wagenknecht LE, Langefeld CD, Bowden DW, Palmer ND.

Mol Genet Metab. 2012 Dec;107(4):721-8. doi: 10.1016/j.ymgme.2012.10.003. Epub 2012 Oct 13.


Genetic variants in selenoprotein P plasma 1 gene (SEPP1) are associated with fasting insulin and first phase insulin response in Hispanics.

Hellwege JN, Palmer ND, Ziegler JT, Langefeld CD, Lorenzo C, Norris JM, Takamura T, Bowden DW.

Gene. 2014 Jan 15;534(1):33-9. doi: 10.1016/j.gene.2013.10.035. Epub 2013 Oct 24.


Polymorphisms near SOCS3 are associated with obesity and glucose homeostasis traits in Hispanic Americans from the Insulin Resistance Atherosclerosis Family Study.

Talbert ME, Langefeld CD, Ziegler J, Mychaleckyj JC, Haffner SM, Norris JM, Bowden DW.

Hum Genet. 2009 Mar;125(2):153-62. doi: 10.1007/s00439-008-0608-3. Epub 2008 Dec 13.


Preferential fat deposition in subcutaneous versus visceral depots is associated with insulin sensitivity.

McLaughlin T, Lamendola C, Liu A, Abbasi F.

J Clin Endocrinol Metab. 2011 Nov;96(11):E1756-60. doi: 10.1210/jc.2011-0615. Epub 2011 Aug 24.


PET imaging reveals distinctive roles for different regional adipose tissue depots in systemic glucose metabolism in nonobese humans.

Ng JM, Azuma K, Kelley C, Pencek R, Radikova Z, Laymon C, Price J, Goodpaster BH, Kelley DE.

Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1134-41. doi: 10.1152/ajpendo.00282.2012. Epub 2012 Sep 11.


INSIG2 SNPs associated with obesity and glucose homeostasis traits in Hispanics: the IRAS Family Study.

Talbert ME, Langefeld CD, Ziegler JT, Haffner SM, Norris JM, Bowden DW.

Obesity (Silver Spring). 2009 Aug;17(8):1554-62. doi: 10.1038/oby.2009.94. Epub 2009 Apr 9.


The apoB-100 gene EcoRI polymorphism influences the relationship between features of the insulin resistance syndrome and the hyper-apoB and dense LDL phenotype in men.

Vohl MC, Tchernof A, Dionne FT, Moorjani S, Prud'homme D, Bouchard C, Nadeau A, Lupien PJ, Despr├ęs JP.

Diabetes. 1996 Oct;45(10):1405-11.


Both subcutaneous and visceral adipose tissue correlate highly with insulin resistance in african americans.

Tulloch-Reid MK, Hanson RL, Sebring NG, Reynolds JC, Premkumar A, Genovese DJ, Sumner AE.

Obes Res. 2004 Aug;12(8):1352-9.

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