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Items: 1 to 20 of 128


Identification of yeast genes that confer resistance to chitosan oligosaccharide (COS) using chemogenomics.

Jaime MD, Lopez-Llorca LV, Conesa A, Lee AY, Proctor M, Heisler LE, Gebbia M, Giaever G, Westwood JT, Nislow C.

BMC Genomics. 2012 Jun 22;13:267. doi: 10.1186/1471-2164-13-267.


Transcriptional response of Saccharomyces cerevisiae to the plasma membrane-perturbing compound chitosan.

Zakrzewska A, Boorsma A, Brul S, Hellingwerf KJ, Klis FM.

Eukaryot Cell. 2005 Apr;4(4):703-15.


Yeast ARL1 encodes a regulator of K+ influx.

Munson AM, Haydon DH, Love SL, Fell GL, Palanivel VR, Rosenwald AG.

J Cell Sci. 2004 May 1;117(Pt 11):2309-20.


Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans.

Barker KS, Crisp S, Wiederhold N, Lewis RE, Bareither B, Eckstein J, Barbuch R, Bard M, Rogers PD.

J Antimicrob Chemother. 2004 Aug;54(2):376-85. Epub 2004 Jun 16.


Gene expression and evolution of antifungal drug resistance.

Anderson JB, Sirjusingh C, Syed N, Lafayette S.

Antimicrob Agents Chemother. 2009 May;53(5):1931-6. doi: 10.1128/AAC.01315-08. Epub 2009 Mar 9.


Comparison of the influence of small GTPases Arl1 and Ypt6 on yeast cells' tolerance to various stress factors.

Marešová L, Vydarený T, Sychrová H.

FEMS Yeast Res. 2012 May;12(3):332-40. doi: 10.1111/j.1567-1364.2011.00780.x. Epub 2012 Jan 10.


The yeast genes, ARL1 and CCZ1, interact to control membrane traffic and ion homeostasis.

Love SL, Manlandro CM, Testa CJ, Thomas AE, Tryggestad KE, Rosenwald AG.

Biochem Biophys Res Commun. 2004 Jul 2;319(3):840-6.


Disruption of protein synthesis as antifungal mode of action by chitosan.

Galván Márquez I, Akuaku J, Cruz I, Cheetham J, Golshani A, Smith ML.

Int J Food Microbiol. 2013 Jun 3;164(1):108-12. doi: 10.1016/j.ijfoodmicro.2013.03.025. Epub 2013 Apr 6.


Chemosensitization prevents tolerance of Aspergillus fumigatus to antimycotic drugs.

Kim J, Campbell B, Mahoney N, Chan K, Molyneux R, May G.

Biochem Biophys Res Commun. 2008 Jul 18;372(1):266-71. doi: 10.1016/j.bbrc.2008.05.030. Epub 2008 May 16.


The novel equisetin-like compound, TA-289, causes aberrant mitochondrial morphology which is independent of the production of reactive oxygen species in Saccharomyces cerevisiae.

Quek NC, Matthews JH, Bloor SJ, Jones DA, Bircham PW, Heathcott RW, Atkinson PH.

Mol Biosyst. 2013 Aug;9(8):2125-33. doi: 10.1039/c3mb70056a. Epub 2013 May 28.


Dysregulated Arl1, a regulator of post-Golgi vesicle tethering, can inhibit endosomal transport and cell proliferation in yeast.

Benjamin JJ, Poon PP, Drysdale JD, Wang X, Singer RA, Johnston GC.

Mol Biol Cell. 2011 Jul 1;22(13):2337-47. doi: 10.1091/mbc.E10-09-0765. Epub 2011 May 11.


High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions.

Hoepfner D, Helliwell SB, Sadlish H, Schuierer S, Filipuzzi I, Brachat S, Bhullar B, Plikat U, Abraham Y, Altorfer M, Aust T, Baeriswyl L, Cerino R, Chang L, Estoppey D, Eichenberger J, Frederiksen M, Hartmann N, Hohendahl A, Knapp B, Krastel P, Melin N, Nigsch F, Oakeley EJ, Petitjean V, Petersen F, Riedl R, Schmitt EK, Staedtler F, Studer C, Tallarico JA, Wetzel S, Fishman MC, Porter JA, Movva NR.

Microbiol Res. 2014 Feb-Mar;169(2-3):107-20. doi: 10.1016/j.micres.2013.11.004. Epub 2013 Dec 1.


Genetic prerequisites for additive or synergistic actions of 5-fluorocytosine and fluconazole in baker's yeast.

Paluszynski JP, Klassen R, Meinhardt F.

Microbiology. 2008 Oct;154(Pt 10):3154-64. doi: 10.1099/mic.0.2008/020107-0.


Membrane-active compounds activate the transcription factors Pdr1 and Pdr3 connecting pleiotropic drug resistance and membrane lipid homeostasis in saccharomyces cerevisiae.

Schüller C, Mamnun YM, Wolfger H, Rockwell N, Thorner J, Kuchler K.

Mol Biol Cell. 2007 Dec;18(12):4932-44. Epub 2007 Sep 19.


Exploring gene function and drug action using chemogenomic dosage assays.

Ericson E, Hoon S, St Onge RP, Giaever G, Nislow C.

Methods Enzymol. 2010;470:233-55. doi: 10.1016/S0076-6879(10)70010-0. Epub 2010 Mar 1.


Cellular processes and pathways that protect Saccharomyces cerevisiae cells against the plasma membrane-perturbing compound chitosan.

Zakrzewska A, Boorsma A, Delneri D, Brul S, Oliver SG, Klis FM.

Eukaryot Cell. 2007 Apr;6(4):600-8. Epub 2007 Jan 26.


Neurospora crassa transcriptomics reveals oxidative stress and plasma membrane homeostasis biology genes as key targets in response to chitosan.

Lopez-Moya F, Kowbel D, Nueda MJ, Palma-Guerrero J, Glass NL, Lopez-Llorca LV.

Mol Biosyst. 2016 Feb;12(2):391-403. doi: 10.1039/c5mb00649j.


Divergent functions of three Candida albicans zinc-cluster transcription factors (CTA4, ASG1 and CTF1) complementing pleiotropic drug resistance in Saccharomyces cerevisiae.

Coste AT, Ramsdale M, Ischer F, Sanglard D.

Microbiology. 2008 May;154(Pt 5):1491-501. doi: 10.1099/mic.0.2007/016063-0.


Mon2 is a negative regulator of the monomeric G protein, Arl1.

Manlandro CM, Palanivel VR, Schorr EB, Mihatov N, Antony AA, Rosenwald AG.

FEMS Yeast Res. 2012 Sep;12(6):637-50. doi: 10.1111/j.1567-1364.2012.00814.x. Epub 2012 Jun 18.

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