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Items: 1 to 20 of 116

1.

Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation.

Dranka BP, Zielonka J, Kanthasamy AG, Kalyanaraman B.

J Neurochem. 2012 Sep;122(5):941-51. doi: 10.1111/j.1471-4159.2012.07836.x. Epub 2012 Jul 11.

2.

Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death.

Giordano S, Lee J, Darley-Usmar VM, Zhang J.

PLoS One. 2012;7(9):e44610. doi: 10.1371/journal.pone.0044610. Epub 2012 Sep 6.

3.

Impairment of Atg5-dependent autophagic flux promotes paraquat- and MPP⁺-induced apoptosis but not rotenone or 6-hydroxydopamine toxicity.

Garcia-Garcia A, Anandhan A, Burns M, Chen H, Zhou Y, Franco R.

Toxicol Sci. 2013 Nov;136(1):166-82. doi: 10.1093/toxsci/kft188. Epub 2013 Aug 31.

4.
5.

Thioredoxin reductase deficiency potentiates oxidative stress, mitochondrial dysfunction and cell death in dopaminergic cells.

Lopert P, Day BJ, Patel M.

PLoS One. 2012;7(11):e50683. doi: 10.1371/journal.pone.0050683. Epub 2012 Nov 30.

6.

Alterations in energy/redox metabolism induced by mitochondrial and environmental toxins: a specific role for glucose-6-phosphate-dehydrogenase and the pentose phosphate pathway in paraquat toxicity.

Lei S, Zavala-Flores L, Garcia-Garcia A, Nandakumar R, Huang Y, Madayiputhiya N, Stanton RC, Dodds ED, Powers R, Franco R.

ACS Chem Biol. 2014 Sep 19;9(9):2032-48. doi: 10.1021/cb400894a. Epub 2014 Jul 7.

7.

The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited.

Nakamura K, Bindokas VP, Marks JD, Wright DA, Frim DM, Miller RJ, Kang UJ.

Mol Pharmacol. 2000 Aug;58(2):271-8.

8.

Paraquat neurotoxicity is distinct from that of MPTP and rotenone.

Richardson JR, Quan Y, Sherer TB, Greenamyre JT, Miller GW.

Toxicol Sci. 2005 Nov;88(1):193-201. Epub 2005 Sep 1.

PMID:
16141438
9.

The mitochondrial complex I inhibitor annonacin is toxic to mesencephalic dopaminergic neurons by impairment of energy metabolism.

Lannuzel A, Michel PP, Höglinger GU, Champy P, Jousset A, Medja F, Lombès A, Darios F, Gleye C, Laurens A, Hocquemiller R, Hirsch EC, Ruberg M.

Neuroscience. 2003;121(2):287-96.

PMID:
14521988
10.
11.

Bioenergetic adaptation in response to autophagy regulators during rotenone exposure.

Giordano S, Dodson M, Ravi S, Redmann M, Ouyang X, Darley Usmar VM, Zhang J.

J Neurochem. 2014 Dec;131(5):625-33. doi: 10.1111/jnc.12844. Epub 2014 Aug 21.

12.

Toxin-induced models of Parkinson's disease.

Bové J, Prou D, Perier C, Przedborski S.

NeuroRx. 2005 Jul;2(3):484-94. Review.

13.

Alterations in mitochondrial dynamics induced by tebufenpyrad and pyridaben in a dopaminergic neuronal cell culture model.

Charli A, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG.

Neurotoxicology. 2016 Mar;53:302-13. doi: 10.1016/j.neuro.2015.06.007. Epub 2015 Jul 2.

14.

Bioenergetic and proteolytic defects in fibroblasts from patients with sporadic Parkinson's disease.

Ambrosi G, Ghezzi C, Sepe S, Milanese C, Payan-Gomez C, Bombardieri CR, Armentero MT, Zangaglia R, Pacchetti C, Mastroberardino PG, Blandini F.

Biochim Biophys Acta. 2014 Sep;1842(9):1385-94. doi: 10.1016/j.bbadis.2014.05.008. Epub 2014 May 20.

15.

Chronic inhalation of rotenone or paraquat does not induce Parkinson's disease symptoms in mice or rats.

Rojo AI, Cavada C, de Sagarra MR, Cuadrado A.

Exp Neurol. 2007 Nov;208(1):120-6. Epub 2007 Aug 22.

PMID:
17880941
16.

Compartmentalized oxidative stress in dopaminergic cell death induced by pesticides and complex I inhibitors: distinct roles of superoxide anion and superoxide dismutases.

Rodriguez-Rocha H, Garcia-Garcia A, Pickett C, Li S, Jones J, Chen H, Webb B, Choi J, Zhou Y, Zimmerman MC, Franco R.

Free Radic Biol Med. 2013 Aug;61:370-83. doi: 10.1016/j.freeradbiomed.2013.04.021. Epub 2013 Apr 19.

17.

Genetic reduction of mitochondrial complex I function does not lead to loss of dopamine neurons in vivo.

Kim HW, Choi WS, Sorscher N, Park HJ, Tronche F, Palmiter RD, Xia Z.

Neurobiol Aging. 2015 Sep;36(9):2617-27. doi: 10.1016/j.neurobiolaging.2015.05.008. Epub 2015 May 16.

18.

Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂.

Cantu D, Fulton RE, Drechsel DA, Patel M.

J Neurochem. 2011 Jul;118(1):79-92. doi: 10.1111/j.1471-4159.2011.07290.x. Epub 2011 May 19.

20.

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