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Items: 1 to 20 of 116

1.

Gene- and cell-based bio-artificial pacemaker: what basic and translational lessons have we learned?

Li RA.

Gene Ther. 2012 Jun;19(6):588-95. doi: 10.1038/gt.2012.33. Review.

2.

Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome model.

Tse HF, Xue T, Lau CP, Siu CW, Wang K, Zhang QY, Tomaselli GF, Akar FG, Li RA.

Circulation. 2006 Sep 5;114(10):1000-11. Epub 2006 Aug 21.

3.

Dynamic action potential clamp as a powerful tool in the development of a gene-based bio-pacemaker.

Verkerk AO, Zegers JG, van Ginneken AC, Wilders R.

Conf Proc IEEE Eng Med Biol Soc. 2008;2008:133-6. doi: 10.1109/IEMBS.2008.4649108.

PMID:
19162611
4.

Biological pacemakers as a therapy for cardiac arrhythmias.

Marbán E, Cho HC.

Curr Opin Cardiol. 2008 Jan;23(1):46-54. doi: 10.1097/HCO.0b013e3282f30416. Review.

PMID:
18281827
5.

Gene Delivery for the Generation of Bioartificial Pacemaker.

Chan PK, Li RA.

Methods Mol Biol. 2017;1521:293-306.

PMID:
27910058
6.

Automaticity and conduction properties of bio-artificial pacemakers assessed in an in vitro monolayer model of neonatal rat ventricular myocytes.

Chan YC, Tse HF, Siu CW, Wang K, Li RA.

Europace. 2010 Aug;12(8):1178-87. doi: 10.1093/europace/euq120. Epub 2010 May 14.

7.

In vitro characterization of HCN channel kinetics and frequency dependence in myocytes predicts biological pacemaker functionality.

Zhao X, Bucchi A, Oren RV, Kryukova Y, Dun W, Clancy CE, Robinson RB.

J Physiol. 2009 Apr 1;587(Pt 7):1513-25. doi: 10.1113/jphysiol.2008.163444. Epub 2009 Jan 26.

8.

Gene therapy for restoring heart rhythm.

Boink GJ, Robinson RB.

J Cardiovasc Pharmacol Ther. 2014 Sep;19(5):426-38. doi: 10.1177/1074248414528575. Epub 2014 Apr 17. Review.

PMID:
24742766
10.

The past, present, and future of pacemaker therapies.

Boink GJ, Christoffels VM, Robinson RB, Tan HL.

Trends Cardiovasc Med. 2015 Nov;25(8):661-73. doi: 10.1016/j.tcm.2015.02.005. Epub 2015 Feb 20. Review.

PMID:
26001958
11.

Biological pacemakers based on I(f).

Rosen MR, Brink PR, Cohen IS, Robinson RB.

Med Biol Eng Comput. 2007 Feb;45(2):157-66. Epub 2006 May 31. Review.

PMID:
17629762
12.

Funny channels in the control of cardiac rhythm and mode of action of selective blockers.

DiFrancesco D.

Pharmacol Res. 2006 May;53(5):399-406. Epub 2006 Mar 27. Review.

PMID:
16638640
13.

Molecular regulation and pharmacology of pacemaker channels.

Bois P, Guinamard R, Chemaly AE, Faivre JF, Bescond J.

Curr Pharm Des. 2007;13(23):2338-49. Review.

PMID:
17692005
14.

Mesenchymal stem cells as a gene delivery system to create biological pacemaker cells in vitro.

Yang XJ, Zhou YF, Li HX, Han LH, Jiang WP.

J Int Med Res. 2008 Sep-Oct;36(5):1049-55.

PMID:
18831900
15.

cAMP sensitivity of HCN pacemaker channels determines basal heart rate but is not critical for autonomic rate control.

Schweizer PA, Duhme N, Thomas D, Becker R, Zehelein J, Draguhn A, Bruehl C, Katus HA, Koenen M.

Circ Arrhythm Electrophysiol. 2010 Oct;3(5):542-52. doi: 10.1161/CIRCEP.110.949768. Epub 2010 Aug 7.

16.

Genetic isolation of stem cell-derived pacemaker-nodal cardiac myocytes.

Hashem SI, Claycomb WC.

Mol Cell Biochem. 2013 Nov;383(1-2):161-71. doi: 10.1007/s11010-013-1764-x. Epub 2013 Jul 23.

PMID:
23877224
17.

Insights into sick sinus syndrome from an inducible mouse model.

Herrmann S, Fabritz L, Layh B, Kirchhof P, Ludwig A.

Cardiovasc Res. 2011 Apr 1;90(1):38-48. doi: 10.1093/cvr/cvq390. Epub 2010 Dec 30.

PMID:
21193513
18.

Characterization of a right atrial subsidiary pacemaker and acceleration of the pacing rate by HCN over-expression.

Morris GM, D'Souza A, Dobrzynski H, Lei M, Choudhury M, Billeter R, Kryukova Y, Robinson RB, Kingston PA, Boyett MR.

Cardiovasc Res. 2013 Oct 1;100(1):160-9. doi: 10.1093/cvr/cvt164. Epub 2013 Jun 19.

PMID:
23787003
19.

Molecular diversity of pacemaker ion channels.

Kaupp UB, Seifert R.

Annu Rev Physiol. 2001;63:235-57. Review.

PMID:
11181956
20.

The role of the funny current in pacemaker activity.

DiFrancesco D.

Circ Res. 2010 Feb 19;106(3):434-46. doi: 10.1161/CIRCRESAHA.109.208041. Review.

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