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Items: 1 to 20 of 98

1.

Perlecan domain V is upregulated in human brain arteriovenous malformation and could mediate the vascular endothelial growth factor effect in lesional tissue.

Kahle MP, Lee B, Pourmohamad T, Cunningham A, Su H, Kim H, Chen Y, McCulloch CE, Barbaro NM, Lawton MT, Young WL, Bix GJ.

Neuroreport. 2012 Jul 11;23(10):627-30. doi: 10.1097/WNR.0b013e3283554c5c.

2.

Perlecan Domain V induces VEGf secretion in brain endothelial cells through integrin α5β1 and ERK-dependent signaling pathways.

Clarke DN, Al Ahmad A, Lee B, Parham C, Auckland L, Fertala A, Kahle M, Shaw CS, Roberts J, Bix GJ.

PLoS One. 2012;7(9):e45257. doi: 10.1371/journal.pone.0045257. Epub 2012 Sep 17.

3.

Perlecan domain V inhibits amyloid-β induced brain endothelial cell toxicity and restores angiogenic function.

Parham C, Auckland L, Rachwal J, Clarke D, Bix G.

J Alzheimers Dis. 2014;38(2):415-23. doi: 10.3233/JAD-130683.

4.

Perlecan domain V modulates astrogliosis in vitro and after focal cerebral ischemia through multiple receptors and increased nerve growth factor release.

Al-Ahmad AJ, Lee B, Saini M, Bix GJ.

Glia. 2011 Dec;59(12):1822-40. doi: 10.1002/glia.21227. Epub 2011 Aug 17.

PMID:
21850672
5.

Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism.

Goyal A, Pal N, Concannon M, Paul M, Doran M, Poluzzi C, Sekiguchi K, Whitelock JM, Neill T, Iozzo RV.

J Biol Chem. 2011 Jul 22;286(29):25947-62. doi: 10.1074/jbc.M111.243626. Epub 2011 May 19.

6.

Reduced expression of integrin alphavbeta8 is associated with brain arteriovenous malformation pathogenesis.

Su H, Kim H, Pawlikowska L, Kitamura H, Shen F, Cambier S, Markovics J, Lawton MT, Sidney S, Bollen AW, Kwok PY, Reichardt L, Young WL, Yang GY, Nishimura SL.

Am J Pathol. 2010 Feb;176(2):1018-27. doi: 10.2353/ajpath.2010.090453. Epub 2009 Dec 17.

7.

Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents.

Lee B, Clarke D, Al Ahmad A, Kahle M, Parham C, Auckland L, Shaw C, Fidanboylu M, Orr AW, Ogunshola O, Fertala A, Thomas SA, Bix GJ.

J Clin Invest. 2011 Aug;121(8):3005-23. doi: 10.1172/JCI46358. Epub 2011 Jul 11. Erratum in: J Clin Invest. 2012 Feb 1;122(2):777.

8.

Alternatively Activated Macrophages Play an Important Role in Vascular Remodeling and Hemorrhaging in Patients with Brain Arteriovenous Malformation.

Nakamura Y, Sugita Y, Nakashima S, Okada Y, Yoshitomi M, Kimura Y, Miyoshi H, Morioka M, Ohshima K.

J Stroke Cerebrovasc Dis. 2016 Mar;25(3):600-9. doi: 10.1016/j.jstrokecerebrovasdis.2015.11.034. Epub 2015 Dec 24.

PMID:
26725126
9.

Receptors of the Notch signaling pathway are associated with hemorrhage of brain arteriovenous malformations.

Li S, Wang R, Wang Y, Li H, Zheng J, Duan R, Zhao J.

Mol Med Rep. 2014 Jun;9(6):2233-8. doi: 10.3892/mmr.2014.2061. Epub 2014 Mar 18.

PMID:
24643729
10.

Ephrin B2 and EphB4 selectively mark arterial and venous vessels in cerebral arteriovenous malformation.

Bai J, Wang YJ, Liu L, Zhao YL.

J Int Med Res. 2014 Apr;42(2):405-15. doi: 10.1177/0300060513478091. Epub 2014 Feb 11.

PMID:
24517927
11.

Tie endothelial cell-specific receptor tyrosine kinase is upregulated in the vasculature of arteriovenous malformations.

Hatva E, Jääskeläinen J, Hirvonen H, Alitalo K, Haltia M.

J Neuropathol Exp Neurol. 1996 Nov;55(11):1124-33.

PMID:
8939195
12.

Coexpression of angiogenic factors in brain arteriovenous malformations.

Hashimoto T, Wu Y, Lawton MT, Yang GY, Barbaro NM, Young WL.

Neurosurgery. 2005 May;56(5):1058-65; discussion 1058-65.

PMID:
15854255
13.

Soluble FLT1 Gene Therapy Alleviates Brain Arteriovenous Malformation Severity.

Zhu W, Shen F, Mao L, Zhan L, Kang S, Sun Z, Nelson J, Zhang R, Zou D, McDougall CM, Lawton MT, Vu TH, Wu Z, Scaria A, Colosi P, Forsayeth J, Su H.

Stroke. 2017 May;48(5):1420-1423. doi: 10.1161/STROKEAHA.116.015713. Epub 2017 Mar 21.

14.

Expression of endothelial cell angiogenesis receptors in human cerebrovascular malformations.

Uranishi R, Baev NI, Ng PY, Kim JH, Awad IA.

Neurosurgery. 2001 Feb;48(2):359-67; discussion 367-8.

PMID:
11220380
15.

A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through alpha5beta1 integrin.

Soro S, Orecchia A, Morbidelli L, Lacal PM, Morea V, Ballmer-Hofer K, Ruffini F, Ziche M, D'Atri S, Zambruno G, Tramontano A, Failla CM.

Blood. 2008 Apr 1;111(7):3479-88. doi: 10.1182/blood-2007-03-077537. Epub 2008 Jan 9.

16.

Integrin β8 Deletion Enhances Vascular Dysplasia and Hemorrhage in the Brain of Adult Alk1 Heterozygous Mice.

Ma L, Shen F, Jun K, Bao C, Kuo R, Young WL, Nishimura SL, Su H.

Transl Stroke Res. 2016 Dec;7(6):488-496. Epub 2016 Jun 29.

17.

Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease.

Murphy PA, Lu G, Shiah S, Bollen AW, Wang RA.

Lab Invest. 2009 Sep;89(9):971-82. doi: 10.1038/labinvest.2009.62. Epub 2009 Jun 22. Erratum in: Lab Invest. 2009 Sep;89(9):1071.

18.

Investigating the role of perlecan domain V in post-ischemic cerebral angiogenesis.

Marcelo A, Bix G.

Methods Mol Biol. 2014;1135:331-41. doi: 10.1007/978-1-4939-0320-7_27.

PMID:
24510876
19.

Expression of vascular endothelial growth factors and their receptors in and around intracranial arteriovenous malformations.

Koizumi T, Shiraishi T, Hagihara N, Tabuchi K, Hayashi T, Kawano T.

Neurosurgery. 2002 Jan;50(1):117-24; discussion 124-6. Erratum in: Neurosurgery. 2002 Jul;51(1):211..

PMID:
11844242
20.

Leptin plays a role in ruptured human brain arteriovenous malformations.

Xie Q, Chen XC, Gong Y, Gu YX.

Acta Neurochir Suppl. 2008;105:221-4.

PMID:
19066113

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