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Items: 1 to 20 of 212

1.

Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1).

Durand A, Donahue B, Peignon G, Letourneur F, Cagnard N, Slomianny C, Perret C, Shroyer NF, Romagnolo B.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8965-70. doi: 10.1073/pnas.1201652109. Epub 2012 May 14.

2.

Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells.

Kim TH, Escudero S, Shivdasani RA.

Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3932-7. doi: 10.1073/pnas.1113890109. Epub 2012 Feb 21.

3.

Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells.

Farin HF, Van Es JH, Clevers H.

Gastroenterology. 2012 Dec;143(6):1518-1529.e7. doi: 10.1053/j.gastro.2012.08.031. Epub 2012 Aug 23.

PMID:
22922422
4.

Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts.

Kabiri Z, Greicius G, Madan B, Biechele S, Zhong Z, Zaribafzadeh H, Edison, Aliyev J, Wu Y, Bunte R, Williams BO, Rossant J, Virshup DM.

Development. 2014 Jun;141(11):2206-15.

5.

Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche.

Das S, Yu S, Sakamori R, Vedula P, Feng Q, Flores J, Hoffman A, Fu J, Stypulkowski E, Rodriguez A, Dobrowolski R, Harada A, Hsu W, Bonder EM, Verzi MP, Gao N.

Development. 2015 Jun 15;142(12):2147-62. doi: 10.1242/dev.121046. Epub 2015 May 26.

6.

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.

Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY.

Science. 2001 Dec 7;294(5549):2155-8.

7.

Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression.

Kim TH, Shivdasani RA.

J Biol Chem. 2011 Apr 1;286(13):11427-33. doi: 10.1074/jbc.M110.188797. Epub 2011 Jan 31.

8.

Evidence for a crucial role of paneth cells in mediating the intestinal response to injury.

Parry L, Young M, El Marjou F, Clarke AR.

Stem Cells. 2013 Apr;31(4):776-85. doi: 10.1002/stem.1326.

9.

Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.

Andreu P, Colnot S, Godard C, Gad S, Chafey P, Niwa-Kawakita M, Laurent-Puig P, Kahn A, Robine S, Perret C, Romagnolo B.

Development. 2005 Mar;132(6):1443-51. Epub 2005 Feb 16.

10.

Interplay between metabolic identities in the intestinal crypt supports stem cell function.

Rodríguez-Colman MJ, Schewe M, Meerlo M, Stigter E, Gerrits J, Pras-Raves M, Sacchetti A, Hornsveld M, Oost KC, Snippert HJ, Verhoeven-Duif N, Fodde R, Burgering BM.

Nature. 2017 Mar 16;543(7645):424-427. doi: 10.1038/nature21673. Epub 2017 Mar 8.

PMID:
28273069
11.

Wnt signalling induces maturation of Paneth cells in intestinal crypts.

van Es JH, Jay P, Gregorieff A, van Gijn ME, Jonkheer S, Hatzis P, Thiele A, van den Born M, Begthel H, Brabletz T, Taketo MM, Clevers H.

Nat Cell Biol. 2005 Apr;7(4):381-6. Epub 2005 Mar 20.

PMID:
15778706
12.

The intestine-specific homeobox gene Cdx2 induces expression of the basic helix-loop-helix transcription factor Math1.

Mutoh H, Sakamoto H, Hayakawa H, Arao Y, Satoh K, Nokubi M, Sugano K.

Differentiation. 2006 Jul;74(6):313-21.

PMID:
16831200
13.

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine.

Heuberger J, Kosel F, Qi J, Grossmann KS, Rajewsky K, Birchmeier W.

Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3472-7. doi: 10.1073/pnas.1309342111. Epub 2014 Feb 18.

14.

A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation.

Andreu P, Peignon G, Slomianny C, Taketo MM, Colnot S, Robine S, Lamarque D, Laurent-Puig P, Perret C, Romagnolo B.

Dev Biol. 2008 Dec 15;324(2):288-96. doi: 10.1016/j.ydbio.2008.09.027. Epub 2008 Oct 4.

15.

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration.

Lindemans CA, Calafiore M, Mertelsmann AM, O'Connor MH, Dudakov JA, Jenq RR, Velardi E, Young LF, Smith OM, Lawrence G, Ivanov JA, Fu YY, Takashima S, Hua G, Martin ML, O'Rourke KP, Lo YH, Mokry M, Romera-Hernandez M, Cupedo T, Dow L, Nieuwenhuis EE, Shroyer NF, Liu C, Kolesnick R, van den Brink MRM, Hanash AM.

Nature. 2015 Dec 24;528(7583):560-564. doi: 10.1038/nature16460. Epub 2015 Dec 9.

16.

Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis.

Shroyer NF, Helmrath MA, Wang VY, Antalffy B, Henning SJ, Zoghbi HY.

Gastroenterology. 2007 Jun;132(7):2478-88. Epub 2007 Mar 24.

PMID:
17570220
17.

RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.

Hilkens J, Timmer NC, Boer M, Ikink GJ, Schewe M, Sacchetti A, Koppens MAJ, Song JY, Bakker ERM.

Gut. 2017 Jun;66(6):1095-1105. doi: 10.1136/gutjnl-2016-311606. Epub 2016 Aug 10.

18.

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts.

Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H.

Nature. 2011 Jan 20;469(7330):415-8. doi: 10.1038/nature09637. Epub 2010 Nov 28.

19.

Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity.

Janeckova L, Fafilek B, Krausova M, Horazna M, Vojtechova M, Alberich-Jorda M, Sloncova E, Galuskova K, Sedlacek R, Anderova M, Korinek V.

Genesis. 2016 Mar;54(3):101-14. doi: 10.1002/dvg.22922. Epub 2016 Feb 16.

20.

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