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Topological and mutational analysis of Saccharomyces cerevisiae Fks1.

Johnson ME, Edlind TD.

Eukaryot Cell. 2012 Jul;11(7):952-60. doi: 10.1128/EC.00082-12. Epub 2012 May 11.


Role for Fks1 in the intrinsic echinocandin resistance of Fusarium solani as evidenced by hybrid expression in Saccharomyces cerevisiae.

Katiyar SK, Edlind TD.

Antimicrob Agents Chemother. 2009 May;53(5):1772-8. doi: 10.1128/AAC.00020-09. Epub 2009 Mar 2.


New Fks hot spot for acquired echinocandin resistance in Saccharomyces cerevisiae and its contribution to intrinsic resistance of Scedosporium species.

Johnson ME, Katiyar SK, Edlind TD.

Antimicrob Agents Chemother. 2011 Aug;55(8):3774-81. doi: 10.1128/AAC.01811-10. Epub 2011 May 16.


Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase.

Mazur P, Morin N, Baginsky W, el-Sherbeini M, Clemas JA, Nielsen JB, Foor F.

Mol Cell Biol. 1995 Oct;15(10):5671-81.


A glucan synthase FKS1 homolog in cryptococcus neoformans is single copy and encodes an essential function.

Thompson JR, Douglas CM, Li W, Jue CK, Pramanik B, Yuan X, Rude TH, Toffaletti DL, Perfect JR, Kurtz M.

J Bacteriol. 1999 Jan;181(2):444-53.


Multiple functional domains of the yeast l,3-beta-glucan synthase subunit Fks1p revealed by quantitative phenotypic analysis of temperature-sensitive mutants.

Okada H, Abe M, Asakawa-Minemura M, Hirata A, Qadota H, Morishita K, Ohnuki S, Nogami S, Ohya Y.

Genetics. 2010 Apr;184(4):1013-24. doi: 10.1534/genetics.109.109892. Epub 2010 Feb 1.


Cloning of the Candida albicans homolog of Saccharomyces cerevisiae GSC1/FKS1 and its involvement in beta-1,3-glucan synthesis.

Mio T, Adachi-Shimizu M, Tachibana Y, Tabuchi H, Inoue SB, Yabe T, Yamada-Okabe T, Arisawa M, Watanabe T, Yamada-Okabe H.

J Bacteriol. 1997 Jul;179(13):4096-105.


A putative plant homolog of the yeast beta-1,3-glucan synthase subunit FKS1 from cotton (Gossypium hirsutum L.) fibers.

Cui X, Shin H, Song C, Laosinchai W, Amano Y, Brown RM Jr.

Planta. 2001 Jun;213(2):223-30.


Homologous subunits of 1,3-beta-glucan synthase are important for spore wall assembly in Saccharomyces cerevisiae.

Ishihara S, Hirata A, Nogami S, Beauvais A, Latge JP, Ohya Y.

Eukaryot Cell. 2007 Feb;6(2):143-56. Epub 2006 Dec 8.


The yeast FKS1 gene encodes a novel membrane protein, mutations in which confer FK506 and cyclosporin A hypersensitivity and calcineurin-dependent growth.

Eng WK, Faucette L, McLaughlin MM, Cafferkey R, Koltin Y, Morris RA, Young PR, Johnson RK, Livi GP.

Gene. 1994 Dec 30;151(1-2):61-71.


The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase.

Douglas CM, Foor F, Marrinan JA, Morin N, Nielsen JB, Dahl AM, Mazur P, Baginsky W, Li W, el-Sherbeini M, et al.

Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12907-11.


Absence of fks1p in lager brewing yeast results in aberrant cell wall composition and improved beer flavor stability.

Wang JJ, Xu WN, Li X, Li J, Li Q.

World J Microbiol Biotechnol. 2014 Jun;30(6):1901-8. doi: 10.1007/s11274-014-1617-0. Epub 2014 Feb 1.


[Overexpression of FKS1 to improve yeast autolysis-stress].

Li J, Wang J, Li Q.

Sheng Wu Gong Cheng Xue Bao. 2015 Sep;31(9):1344-54. Chinese.


Piperazine propanol derivative as a novel antifungal targeting 1,3-beta-D-glucan synthase.

Kondoh O, Inagaki Y, Fukuda H, Mizuguchi E, Ohya Y, Arisawa M, Shimma N, Aoki Y, Sakaitani M, Watanabe T.

Biol Pharm Bull. 2005 Nov;28(11):2138-41.


Up-regulation of the cell integrity pathway in saccharomyces cerevisiae suppresses temperature sensitivity of the pgs1Delta mutant.

Zhong Q, Li G, Gvozdenovic-Jeremic J, Greenberg ML.

J Biol Chem. 2007 Jun 1;282(22):15946-53. Epub 2007 Apr 9.


Molecular Confirmation of the Relationship between Candida guilliermondii Fks1p Naturally Occurring Amino Acid Substitutions and Its Intrinsic Reduced Echinocandin Susceptibility.

Dudiuk C, Macedo D, Leonardelli F, Theill L, Cabeza MS, Gamarra S, Garcia-Effron G.

Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02644-16. doi: 10.1128/AAC.02644-16. Print 2017 May.


Fks1 and Fks2 are functionally redundant but differentially regulated in Candida glabrata: implications for echinocandin resistance.

Katiyar SK, Alastruey-Izquierdo A, Healey KR, Johnson ME, Perlin DS, Edlind TD.

Antimicrob Agents Chemother. 2012 Dec;56(12):6304-9. doi: 10.1128/AAC.00813-12. Epub 2012 Oct 1.

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