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The T-cell receptor repertoire of tumor-infiltrating regulatory T lymphocytes is skewed toward public sequences.

Sainz-Perez A, Lim A, Lemercier B, Leclerc C.

Cancer Res. 2012 Jul 15;72(14):3557-69. doi: 10.1158/0008-5472.CAN-12-0277. Epub 2012 May 9.


Regulatory T cells prevent CD8 T cell maturation by inhibiting CD4 Th cells at tumor sites.

Chaput N, Darrasse-Jèze G, Bergot AS, Cordier C, Ngo-Abdalla S, Klatzmann D, Azogui O.

J Immunol. 2007 Oct 15;179(8):4969-78.


Astrocytoma infiltrating lymphocytes include major T cell clonal expansions confined to the CD8 subset.

Perrin G, Schnuriger V, Quiquerez AL, Saas P, Pannetier C, de Tribolet N, Tiercy JM, Aubry JP, Dietrich PY, Walker PR.

Int Immunol. 1999 Aug;11(8):1337-50.


Antigen-driven T-cell selection in patients with cervical cancer as evidenced by T-cell receptor analysis and recognition of autologous tumor.

Pilch H, Höhn H, Neukirch C, Freitag K, Knapstein PG, Tanner B, Maeurer MJ.

Clin Diagn Lab Immunol. 2002 Mar;9(2):267-78.


Antitumor cytotoxic T-lymphocyte response in human lung carcinoma: identification of a tumor-associated antigen.

Mami-Chouaib F, Echchakir H, Dorothée G, Vergnon I, Chouaib S.

Immunol Rev. 2002 Oct;188:114-21. Review.


Analysis of the T-cell receptor repertoires of tumor-infiltrating conventional and regulatory T cells reveals no evidence for conversion in carcinogen-induced tumors.

Hindley JP, Ferreira C, Jones E, Lauder SN, Ladell K, Wynn KK, Betts GJ, Singh Y, Price DA, Godkin AJ, Dyson J, Gallimore A.

Cancer Res. 2011 Feb 1;71(3):736-46. doi: 10.1158/0008-5472.CAN-10-1797. Epub 2010 Dec 13.


TCR sequences and tissue distribution discriminate the subsets of naïve and activated/memory Treg cells in mice.

Bergot AS, Chaara W, Ruggiero E, Mariotti-Ferrandiz E, Dulauroy S, Schmidt M, von Kalle C, Six A, Klatzmann D.

Eur J Immunol. 2015 May;45(5):1524-34. doi: 10.1002/eji.201445269. Epub 2015 Apr 7.


Regulatory T cell depletion enhances tumor specific CD8 T-cell responses, elicited by tumor antigen NY-ESO-1b in hepatocellular carcinoma patients, in vitro.

Zhang HH, Mei MH, Fei R, Liao WJ, Wang XY, Qin LL, Wang JH, Wei L, Chen HS.

Int J Oncol. 2010 Apr;36(4):841-8.


Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells.

Wong J, Obst R, Correia-Neves M, Losyev G, Mathis D, Benoist C.

J Immunol. 2007 Jun 1;178(11):7032-41.


The significance of Treg cells in defective tumor immunity.

Kosmaczewska A, Ciszak L, Potoczek S, Frydecka I.

Arch Immunol Ther Exp (Warsz). 2008 May-Jun;56(3):181-91. doi: 10.1007/s00005-008-0018-1. Epub 2008 May 30. Review.


Loss of CTL function among high-avidity tumor-specific CD8+ T cells following tumor infiltration.

Janicki CN, Jenkinson SR, Williams NA, Morgan DJ.

Cancer Res. 2008 Apr 15;68(8):2993-3000. doi: 10.1158/0008-5472.CAN-07-5008.


CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer.

Kiniwa Y, Miyahara Y, Wang HY, Peng W, Peng G, Wheeler TM, Thompson TC, Old LJ, Wang RF.

Clin Cancer Res. 2007 Dec 1;13(23):6947-58.

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