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Items: 1 to 20 of 107


NuRD and pluripotency: a complex balancing act.

Hu G, Wade PA.

Cell Stem Cell. 2012 May 4;10(5):497-503. doi: 10.1016/j.stem.2012.04.011. Review.


NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.

Reynolds N, Latos P, Hynes-Allen A, Loos R, Leaford D, O'Shaughnessy A, Mosaku O, Signolet J, Brennecke P, Kalkan T, Costello I, Humphreys P, Mansfield W, Nakagawa K, Strouboulis J, Behrens A, Bertone P, Hendrich B.

Cell Stem Cell. 2012 May 4;10(5):583-94. doi: 10.1016/j.stem.2012.02.020.


Sall4 controls differentiation of pluripotent cells independently of the Nucleosome Remodelling and Deacetylation (NuRD) complex.

Miller A, Ralser M, Kloet SL, Loos R, Nishinakamura R, Bertone P, Vermeulen M, Hendrich B.

Development. 2016 Sep 1;143(17):3074-84. doi: 10.1242/dev.139113. Epub 2016 Jul 28.


The chromatin remodeler Chd4 maintains embryonic stem cell identity by controlling pluripotency- and differentiation-associated genes.

Zhao H, Han Z, Liu X, Gu J, Tang F, Wei G, Jin Y.

J Biol Chem. 2017 May 19;292(20):8507-8519. doi: 10.1074/jbc.M116.770248. Epub 2017 Mar 15.


Ctbp2 Modulates NuRD-Mediated Deacetylation of H3K27 and Facilitates PRC2-Mediated H3K27me3 in Active Embryonic Stem Cell Genes During Exit from Pluripotency.

Kim TW, Kang BH, Jang H, Kwak S, Shin J, Kim H, Lee SE, Lee SM, Lee JH, Kim JH, Kim SY, Cho EJ, Kim JH, Park KS, Che JH, Han DW, Kang MJ, Yi EC, Youn HD.

Stem Cells. 2015 Aug;33(8):2442-55. doi: 10.1002/stem.2046. Epub 2015 May 26.


MBD3/NuRD facilitates induction of pluripotency in a context-dependent manner.

dos Santos RL, Tosti L, Radzisheuskaya A, Caballero IM, Kaji K, Hendrich B, Silva JC.

Cell Stem Cell. 2014 Jul 3;15(1):102-10. doi: 10.1016/j.stem.2014.04.019. Epub 2014 May 15.


Control of embryonic stem cell identity by nucleosome remodeling enzymes.

Fazzio TG, Panning B.

Curr Opin Genet Dev. 2010 Oct;20(5):500-4. doi: 10.1016/j.gde.2010.08.001. Epub 2010 Aug 25. Review.


Chromatin remodeling in embryonic stem cells: regulating the balance between pluripotency and differentiation.

Keenen B, de la Serna IL.

J Cell Physiol. 2009 Apr;219(1):1-7. doi: 10.1002/jcp.21654. Review.


NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells.

Luo M, Ling T, Xie W, Sun H, Zhou Y, Zhu Q, Shen M, Zong L, Lyu G, Zhao Y, Ye T, Gu J, Tao W, Lu Z, Grummt I.

Stem Cells. 2013 Jul;31(7):1278-86. doi: 10.1002/stem.1374.


Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.

Kaji K, Nichols J, Hendrich B.

Development. 2007 Mar;134(6):1123-32. Epub 2007 Feb 7.


Parallel gateways to pluripotency: open chromatin in stem cells and development.

Koh FM, Sachs M, Guzman-Ayala M, Ramalho-Santos M.

Curr Opin Genet Dev. 2010 Oct;20(5):492-9. doi: 10.1016/j.gde.2010.06.002. Epub 2010 Jul 2. Review.


The nucleosome remodeling and deacetylase complex in development and disease.

Basta J, Rauchman M.

Transl Res. 2015 Jan;165(1):36-47. doi: 10.1016/j.trsl.2014.05.003. Epub 2014 May 10. Review.


An epigenetic switch regulates de novo DNA methylation at a subset of pluripotency gene enhancers during embryonic stem cell differentiation.

Petell CJ, Alabdi L, He M, San Miguel P, Rose R, Gowher H.

Nucleic Acids Res. 2016 Sep 19;44(16):7605-17. doi: 10.1093/nar/gkw426. Epub 2016 May 13.


Characterization of Two Distinct Nucleosome Remodeling and Deacetylase (NuRD) Complex Assemblies in Embryonic Stem Cells.

Bode D, Yu L, Tate P, Pardo M, Choudhary J.

Mol Cell Proteomics. 2016 Mar;15(3):878-91. doi: 10.1074/mcp.M115.053207. Epub 2015 Dec 29.


Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming.

Fidalgo M, Faiola F, Pereira CF, Ding J, Saunders A, Gingold J, Schaniel C, Lemischka IR, Silva JC, Wang J.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16202-7. doi: 10.1073/pnas.1208533109. Epub 2012 Sep 17.


Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells.

Yildirim O, Li R, Hung JH, Chen PB, Dong X, Ee LS, Weng Z, Rando OJ, Fazzio TG.

Cell. 2011 Dec 23;147(7):1498-510. doi: 10.1016/j.cell.2011.11.054.


Mi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function.

Dege C, Hagman J.

Immunol Rev. 2014 Sep;261(1):126-40. doi: 10.1111/imr.12209. Review.


HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cells.

Kidder BL, Palmer S.

Nucleic Acids Res. 2012 Apr;40(7):2925-39. doi: 10.1093/nar/gkr1151. Epub 2011 Dec 10.


Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis.

Zhang J, Jackson AF, Naito T, Dose M, Seavitt J, Liu F, Heller EJ, Kashiwagi M, Yoshida T, Gounari F, Petrie HT, Georgopoulos K.

Nat Immunol. 2011 Nov 13;13(1):86-94. doi: 10.1038/ni.2150.


Global transcription in pluripotent embryonic stem cells.

Efroni S, Duttagupta R, Cheng J, Dehghani H, Hoeppner DJ, Dash C, Bazett-Jones DP, Le Grice S, McKay RD, Buetow KH, Gingeras TR, Misteli T, Meshorer E.

Cell Stem Cell. 2008 May 8;2(5):437-47. doi: 10.1016/j.stem.2008.03.021.

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